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234,136 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Structure Author = "Wei, Y."

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Search Summary

This query matches 84 Structures.

Refinements

Structure Determination Methodology

experimental (84)

Scientific Name of Source Organism

	Homo sapiens (34)
	Escherichia coli K-12 (9)
	Escherichia coli (5)
	Bos taurus (3)
	Ecballium elaterium (3)
	Enterococcus faecalis (3)
	Hepacivirus hominis (3)
	Pseudomonas aeruginosa (3)
	Streptomyces scabiei (3)
	Hepatitis C virus genotype 1a (isolate H77) (2)

More...

Taxonomy

	Eukaryota (43)
	Bacteria (35)
	Riboviria (6)
	Duplodnaviria (3)
	Monodnaviria (2)
	Riboviria (RNA viruses and viroids) (2)
	other sequences (1)

Experimental Method

	X-RAY DIFFRACTION (56)
	ELECTRON MICROSCOPY (17)
	SOLUTION NMR (11)

Polymer Entity Type

Protein (84)

Refinement Resolution (Å)

	1.0 - 1.5 (1)
	1.5 - 2.0 (12)
	2.0 - 2.5 (33)
	2.5 - 3.0 (6)
	3.0 - 3.5 (14)
	3.5 - 4.0 (4)
	4.0 - 4.5 (1)
	> 4.5 (2)

Release Date

	1995 - 1999 (11)
	2000 - 2004 (9)
	2005 - 2009 (8)
	2010 - 2014 (14)
	2015 - 2019 (14)
	2020 - 2024 (24)
	2025 - 2029 (4)

Enzyme Classification Name

	Hydrolases (22)
	Isomerases (7)
	Transferases (7)
	Ligases (4)
	Lyases (3)
	Oxidoreductases (1)

Membrane Protein Annotation

	PDBTM (8)
	MemProtMD (6)
	OPM (4)
	mpstruc (1)

Symmetry Type

	Asymmetric (61)
	Cyclic (24)
	Dihedral (2)
	Icosahedral (2)

SCOP Classification

	Alpha and beta proteins (a+b) (16)
	All beta proteins (6)
	Alpha and beta proteins (a/b) (15)
	All alpha proteins (5)
	Artifacts (5)
	Membrane and cell surface proteins and peptides (2)
	Designed proteins (1)

AllSelected

1 to 25 of 84 Structures

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1B62 \| pdb_00001b62	Download File View File

MUTL COMPLEXED WITH ADP

Wei, Y.

(1999) Cell 97: 85-97

Released	1999-04-28
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Escherichia coli K-12
Macromolecule	PROTEIN (MUTL) (protein)
Unique Ligands	ADP, MG

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1ESC \| pdb_00001esc	Download File View File

THE MOLECULAR MECHANISM OF ENANTIORECOGNITION BY ESTERASES

Wei, Y., Schottel, J.L., Derewenda, U., Swenson, L., Patkar, S., Derewenda, Z.S.

(1995) Nat Struct Biol 2: 218-223

Released	1995-10-15
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Streptomyces scabiei
Macromolecule	ESTERASE (protein)

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1ESD \| pdb_00001esd	Download File View File

THE MOLECULAR MECHANISM OF ENANTIORECOGNITION BY ESTERASES

Wei, Y., Schottel, J.L., Derewenda, U., Swenson, L., Patkar, S., Derewenda, Z.S.

(1995) Nat Struct Biol 2: 218-223

Released	1995-10-15
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Streptomyces scabiei
Macromolecule	ESTERASE (protein)
Unique Ligands	VXA

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1ESE \| pdb_00001ese	Download File View File

THE MOLECULAR MECHANISM OF ENANTIORECOGNITION BY ESTERASES

Wei, Y., Schottel, J.L., Derewenda, U., Swenson, L., Patkar, S., Derewenda, Z.S.

(1995) Nat Struct Biol 2: 218-223

Released	1995-10-15
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Streptomyces scabiei
Macromolecule	ESTERASE (protein)
Unique Ligands	DEP

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1F1J \| pdb_00001f1j	Download File View File

CRYSTAL STRUCTURE OF CASPASE-7 IN COMPLEX WITH ACETYL-ASP-GLU-VAL-ASP-CHO

Wei, Y., Charifson, P.S.

(2000) Chem Biol 7: 423-432

Released	2001-05-23
Method	X-RAY DIFFRACTION 2.35 Å
Organisms	Homo sapiens
Macromolecule	ACE-ASP-GLU-VAL-ASP-CHO (protein) CASPASE-7 PROTEASE (protein)
Unique Ligands	SO4

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1FTN \| pdb_00001ftn	Download File View File

CRYSTAL STRUCTURE OF THE HUMAN RHOA/GDP COMPLEX

Wei, Y., Zhang, Y., Derewenda, U., Liu, X., Minor, W., Nakamoto, R.K., Somlyo, A.V., Somlyo, A.P., Derewenda, Z.S.

(1997) Nat Struct Biol 4: 699-703

Released	1998-03-18
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Homo sapiens
Macromolecule	TRANSFORMING PROTEIN RHOA (H12) (protein)
Unique Ligands	GDP, MG

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1GG6 \| pdb_00001gg6	Download File View File

CRYSTAL STRUCTURE OF GAMMA CHYMOTRYPSIN WITH N-ACETYL-PHENYLALANINE TRIFLUOROMETHYL KETONE BOUND AT THE ACTIVE SITE

Neidhart, D., Wei, Y., Cassidy, C., Lin, J., Cleland, W.W., Frey, P.A.

(2001) Biochemistry 40: 2439-2447

Released	2000-09-20
Method	X-RAY DIFFRACTION 1.4 Å
Organisms	Bos taurus
Macromolecule	GAMMA CHYMOTRYPSIN (protein)
Unique Ligands	APF, APL, EDO, SO4

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1GGD \| pdb_00001ggd	Download File View File

CRYSTAL STRUCTURE OF GAMMA CHYMOTRYPSIN WITH N-ACETYL-LEUCIL-PHENYLALANINE ALDEHYDE BOUND AT THE ACTIVE SITE

Neidhart, D., Wei, Y., Cassidy, C., Lin, J., Cleland, W.W., Frey, P.A.

(2000) Biochemistry 40: 2439-2447

Released	2000-09-20
Method	X-RAY DIFFRACTION 1.5 Å
Organisms	Bos taurus
Macromolecule	GAMMA CHYMOTRYPSIN (protein)
Unique Ligands	FAF, SO4

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1JFR \| pdb_00001jfr	Download File View File

CRYSTAL STRUCTURE OF THE STREPTOMYCES EXFOLIATUS LIPASE AT 1.9A RESOLUTION: A MODEL FOR A FAMILY OF PLATELET-ACTIVATING FACTOR ACETYLHYDROLASES

Wei, Y., Derewenda, Z.S.

(1998) Structure 6: 511-519

Released	1998-07-15
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Streptomyces exfoliatus
Macromolecule	LIPASE (protein)

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1JKM \| pdb_00001jkm	Download File View File

BREFELDIN A ESTERASE, A BACTERIAL HOMOLOGUE OF HUMAN HORMONE SENSITIVE LIPASE

Wei, Y., Contreras, A.J., Sheffield, P., Osterlund, T., Derewenda, U., Matern, U.O., Derewenda, Z.S.

(1999) Nat Struct Biol 6: 340-345

Released	1999-02-16
Method	X-RAY DIFFRACTION 1.85 Å
Organisms	Bacillus subtilis
Macromolecule	BREFELDIN A ESTERASE (protein)

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1JXZ \| pdb_00001jxz	Download File View File

Structure of the H90Q mutant of 4-Chlorobenzoyl-Coenzyme A Dehalogenase complexed with 4-hydroxybenzoyl-Coenzyme A (product)

Thoden, J.B., Zhang, W., Wei, Y., Luo, L., Taylor, K.L., Yang, G., Dunaway-Mariano, D., Benning, M.M., Holden, H.M.

(2001) Biochemistry 40: 13474-13482

Released	2001-10-03
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Pseudomonas sp. CBS3
Macromolecule	4-chlorobenzoyl Coenzyme A dehalogenase (protein)
Unique Ligands	BCA, CA, PO4

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1P68 \| pdb_00001p68	Download File View File

Solution structure of S-824, a de novo designed four helix bundle

Wei, Y., Kim, S., Fela, D., Baum, J., Hecht, M.H.

(2003) Proc Natl Acad Sci U S A 100: 13270-13273

Released	2003-11-11
Method	SOLUTION NMR
Organisms	Escherichia coli
Macromolecule	De novo designed protein S-824 (protein)

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1S14 \| pdb_00001s14	Download File View File

Crystal structure of Escherichia coli Topoisomerase IV ParE 24kDa subunit

Wei, Y., Gross, C.H.

(2004) Antimicrob Agents Chemother 48: 1856-1864

Released	2004-05-04
Method	X-RAY DIFFRACTION 2 Å
Organisms	Escherichia coli
Macromolecule	Topoisomerase IV subunit B (protein)
Unique Ligands	NOV

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1S16 \| pdb_00001s16	Download File View File

Crystal Structure of E. coli Topoisomerase IV ParE 43kDa subunit complexed with ADPNP

Wei, Y., Gross, C.H.

(2004) Antimicrob Agents Chemother 48: 1856-1864

Released	2004-05-04
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Escherichia coli
Macromolecule	Topoisomerase IV subunit B (protein)
Unique Ligands	ANP, MG, SO4

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1THT \| pdb_00001tht	Download File View File

STRUCTURE OF A MYRISTOYL-ACP-SPECIFIC THIOESTERASE FROM VIBRIO HARVEYI

Lawson, D.M., Derewenda, U., Serre, L., Ferri, S., Szitter, R., Wei, Y., Meighen, E.A., Derewenda, Z.S.

(1994) Biochemistry 33: 9382-9388

Released	1995-06-07
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Vibrio harveyi
Macromolecule	THIOESTERASE (protein)

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1TIA \| pdb_00001tia	Download File View File

AN UNUSUAL BURIED POLAR CLUSTER IN A FAMILY OF FUNGAL LIPASES

Derewenda, U., Swenson, L., Yamaguchi, S., Wei, Y., Derewenda, Z.S.

(1994) Nat Struct Biol 1: 36-47

Released	1995-01-26
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Penicillium camemberti
Macromolecule	LIPASE (protein)

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1TIB \| pdb_00001tib	Download File View File

CONFORMATIONAL LABILITY OF LIPASES OBSERVED IN THE ABSENCE OF AN OIL-WATER INTERFACE: CRYSTALLOGRAPHIC STUDIES OF ENZYMES FROM THE FUNGI HUMICOLA LANUGINOSA AND RHIZOPUS DELEMAR

Derewenda, U., Swenson, L., Wei, Y., Derewenda, Z.S.

(1994) J Lipid Res 35: 524-534

Released	1995-01-26
Method	X-RAY DIFFRACTION 1.84 Å
Organisms	Thermomyces lanuginosus
Macromolecule	LIPASE (protein)

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1TL6 \| pdb_00001tl6	Download File View File

Solution structure of T4 bacteriphage AsiA monomer

Lambert, L.J., Wei, Y., Schirf, V., Demeler, B., Werner, M.H.

(2004) EMBO J 23: 2952-2962

Released	2005-06-21
Method	SOLUTION NMR
Organisms	Tequatrovirus T4
Macromolecule	10 kDa anti-sigma factor (protein)

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1TLH \| pdb_00001tlh	Download File View File

T4 AsiA bound to sigma70 region 4

Lambert, L.J., Wei, Y., Schirf, V., Demeler, B., Werner, M.H.

(2004) EMBO J 23: 2952-2962

Released	2004-11-23
Method	SOLUTION NMR
Organisms	Escherichia coli Tequatrovirus T4
Macromolecule	10 kDa anti-sigma factor (protein) RNA polymerase sigma factor rpoD (protein)

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1TTY \| pdb_00001tty	Download File View File

Solution structure of sigma A region 4 from Thermotoga maritima

Lambert, L.J., Wei, Y., Schirf, V., Demeler, B., Werner, M.H.

(2004) EMBO J 23: 2952-2962

Released	2004-11-23
Method	SOLUTION NMR
Organisms	Thermotoga maritima
Macromolecule	RNA polymerase sigma factor rpoD (protein)

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1WAB \| pdb_00001wab	Download File View File

PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE

Ho, Y.S., Swenson, L., Derewenda, U., Serre, L., Wei, Y., Dauter, Z., Hattori, M., Aoki, J., Arai, H., Adachi, T., Inoue, K., Derewenda, Z.S.

(1997) Nature 385: 89-93

Released	1997-11-12
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Bos taurus
Macromolecule	PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE (protein)
Unique Ligands	ACT

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2GF5 \| pdb_00002gf5	Download File View File

Structure of intact FADD (MORT1)

Carrington, P.E., Sandu, C., Wei, Y., Hill, J.M., Morisawa, G., Huang, T., Gavathiotis, E., Wei, Y., Werner, M.H.

(2006) Mol Cell 22: 599-610

Released	2006-06-27
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	FADD protein (protein)

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2LS7 \| pdb_00002ls7	Download File View File

High Definition Solution Structure of PED/PEA-15 Death Effector Domain

Twomey, E.C., Wei, Y.

(2012) Biochem Biophys Res Commun 424: 141-146

Released	2012-08-08
Method	SOLUTION NMR
Organisms	Mus musculus
Macromolecule	Astrocytic phosphoprotein PEA-15 (protein)

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2OI0 \| pdb_00002oi0	Download File View File

Crystal structure analysis 0f the TNF-a Coverting Enzyme (TACE) in complexed with Aryl-sulfonamide

Wei, Y., Rao, G.B., Bandarage, U.K.

(2007) Bioorg Med Chem Lett 17: 2250-2253

Released	2007-11-27
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	TNF- a Converting Enzyme (TACE) (protein)
Unique Ligands	283, ZN

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2OIN \| pdb_00002oin	Download File View File

crystal structure of HCV NS3-4A R155K mutant

Wei, Y.

(2007) J Biological Chem 282: 22619-22628

Released	2007-06-05
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Hepacivirus hominis synthetic construct
Macromolecule	NS4A peptide (protein) Polyprotein (protein)
Unique Ligands	ZN

1 to 25 of 84 Structures

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification

1B62 | pdb_00001b62

1ESC | pdb_00001esc

1ESD | pdb_00001esd

1ESE | pdb_00001ese

1F1J | pdb_00001f1j

1FTN | pdb_00001ftn

1GG6 | pdb_00001gg6

1GGD | pdb_00001ggd

1JFR | pdb_00001jfr

1JKM | pdb_00001jkm

1JXZ | pdb_00001jxz

1P68 | pdb_00001p68

1S14 | pdb_00001s14

1S16 | pdb_00001s16

1THT | pdb_00001tht

1TIA | pdb_00001tia

1TIB | pdb_00001tib

1TL6 | pdb_00001tl6

1TLH | pdb_00001tlh

1TTY | pdb_00001tty

1WAB | pdb_00001wab

2GF5 | pdb_00002gf5

2LS7 | pdb_00002ls7

2OI0 | pdb_00002oi0

2OIN | pdb_00002oin