8YHX | pdb_00008yhx

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F	PF01935	Helicase HerA, central domain (DUF87)	Helicase HerA, central domain	This entry represents the central domain found in archaeal proteins such as DNA double-strand break repair helicase HerA (EC:3.6.4.12). HerA is a helicase which is able to utilise either 3' or 5' single-stranded DNA extensions for loading and subsequ ...	This entry represents the central domain found in archaeal proteins such as DNA double-strand break repair helicase HerA (EC:3.6.4.12). HerA is a helicase which is able to utilise either 3' or 5' single-stranded DNA extensions for loading and subsequent DNA duplex unwinding [1]. It forms a complex with NurA nuclease, this complex has the 5'-3' DNA end resection activity and is essential for cell viability in the crenarchaeon Sulfolobus islandicus [2]. This domain includes the the central RecA-like catalytic core and a flanking four-helix bundle [3]. The function of this prokaryotic domain is unknown. It contains several conserved aspartates and histidines that could be metal ligands.	Domain
G, H, I, J, K G, H, I, J, K, L, M, N, O, P, Q, R	PF13289	SIR2-like domain (SIR2_2)	SIR2-like domain	-	Family

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F	IPR002789	Helicase HerA, central domain	Domain
A, B, C, D, E A, B, C, D, E, F	IPR008571	Helicase HerA-like	Family
A, B, C, D, E A, B, C, D, E, F	IPR027417	P-loop containing nucleoside triphosphate hydrolase	Homologous Superfamily
G, H, I, J, K G, H, I, J, K, L, M, N, O, P, Q, R	IPR039444	SIR2-like domain	Domain