5IVJ

Linked KDM5A Jmj Domain Bound to the Inhibitor N11 [3-({1-[2-(4,4-difluoropiperidin-1-yl)ethyl]-5-fluoro-1H-indazol-3-yl}amino)pyridine-4-carboxylic acid]

CHAIN

A

High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A - Homo sapiens

Explore Sequence Annotations in 3D

CHAIN A

UNIPROT O76083

SECONDARY STRUCTURE

UNMODELED

EDS ATOMS

OCC WT AVG B

AVERAGE OCCUPANCY

ATOMIC CLASHES

RSRZ

RSR

RSCC

BINDING SITE IBM

BINDING SITE MG

BINDING SITE ZN

METAL COORDINATION ZN

BURIED RESIDUES

ARTIFACT

HYDROPATHY

DISORDER

DISORDERED BINDING

PFAM

CATH

SCOP

ECOD

MOLECULE PROCESSING

ACTIVE SITE

MODIFIED RESIDUE

MUTAGENESIS

DOMAIN

REGION

LOADING 97%

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.