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234,136 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Chemical ID(s) = CHT

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Search Summary

This query matches 68 Structures.

Refinements

Structure Determination Methodology

experimental (68)

Scientific Name of Source Organism

	Homo sapiens (14)
	Streptococcus pneumoniae R6 (12)
	Streptococcus pneumoniae (6)
	Gallus gallus (4)
	Mus musculus (3)
	Oleidesulfovibrio alaskensis G20 (3)
	Corynebacterium glutamicum (2)
	Spinacia oleracea (2)
	Streptococcus pneumoniae TIGR4 (2)
	synthetic construct (2)

More...

Taxonomy

	Bacteria (40)
	Eukaryota (26)
	other sequences (2)
	Archaea (1)
	Duplodnaviria (1)

Experimental Method

	X-RAY DIFFRACTION (54)
	ELECTRON MICROSCOPY (14)

Polymer Entity Type

Protein (68)

Refinement Resolution (Å)

	1.0 - 1.5 (2)
	1.5 - 2.0 (25)
	2.0 - 2.5 (21)
	2.5 - 3.0 (13)
	3.0 - 3.5 (4)
	3.5 - 4.0 (3)

Release Date

	2000 - 2004 (5)
	2005 - 2009 (7)
	2010 - 2014 (14)
	2015 - 2019 (16)
	2020 - 2024 (26)

Enzyme Classification Name

	Oxidoreductases (3)
	Hydrolases (19)
	Lyases (5)
	Transferases (4)

Membrane Protein Annotation

	PDBTM (16)
	MemProtMD (15)
	mpstruc (11)
	OPM (5)

Symmetry Type

	Asymmetric (45)
	Cyclic (23)
	Dihedral (3)

SCOP Classification

	Alpha and beta proteins (a/b) (14)
	All beta proteins (6)
	Artifacts (2)
	Alpha and beta proteins (a+b) (1)

AllSelected

1 to 25 of 68 Structures

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1GVM \| pdb_00001gvm	Download File View File

CHOLINE BINDING DOMAIN OF THE MAJOR AUTOLYSIN (C-LYTA) FROM STREPTOCOCCUS PNEUMONIAE

Fernandez-Tornero, C., Lopez, R., Garcia, E., Gimenez-Gallego, G., Romero, A.

(2002) J Mol Biology 321: 163

Released	2002-08-01
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Streptococcus pneumoniae
Macromolecule	AUTOLYSIN (protein)
Unique Ligands	CHT, DDQ, TRS

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1H8G \| pdb_00001h8g	Download File View File

C-terminal domain of the major autolysin (C-LytA) from Streptococcus pneumoniae

Fernandez-Tornero, C., Garcia, E., Lopez, R., Gimenez-Gallego, G., Romero, A.

(2001) Nat Struct Biol 8: 1020

Released	2002-01-31
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Streptococcus pneumoniae
Macromolecule	MAJOR AUTOLYSIN (protein)
Unique Ligands	CHT

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1HCX \| pdb_00001hcx	Download File View File

Choline binding domain of the major autolysin (C-LytA) from Streptococcus pneumoniae

Fernandez-Tornero, C., Lopez, R., Garcia, E., Gimenez-Gallego, G., Romero, A.

(2001) Nat Struct Biol 8: 1020

Released	2001-11-29
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Streptococcus pneumoniae
Macromolecule	MAJOR AUTOLYSIN (protein)
Unique Ligands	CHT, DDQ, TPT

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1OBA \| pdb_00001oba	Download File View File

Multimodular Pneumococcal Cell Wall Endolysin from phage Cp-1 complexed with choline

Hermoso, J.A., Monterroso, B., Albert, A., Garcia, P., Menendez, M., Martinez-Ripoll, M., Garcia, J.L.

(2003) Structure 11: 1239

Released	2003-10-17
Method	X-RAY DIFFRACTION 2.45 Å
Organisms	Streptococcus phage Cp1
Macromolecule	LYSOZYME (protein)
Unique Ligands	CHT

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1P0M \| pdb_00001p0m	Download File View File

Crystal structure of human butyryl cholinesterase in complex with a choline molecule

Nicolet, Y., Lockridge, O., Masson, P., Fontecilla-Camps, J.C., Nachon, F.

(2003) J Biological Chem 278: 41141-41147

Released	2003-08-05
Method	X-RAY DIFFRACTION 2.38 Å
Organisms	Homo sapiens
Macromolecule	Cholinesterase (protein)
Unique Ligands	CHT, CL, GOL, MES, NAG, SO4
Unique branched monosaccharides	FUC, NAG

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2FY3 \| pdb_00002fy3	Download File View File

Structures of ligand bound human choline acetyltransferase provides insight into regulation of acetylcholine synthesis

Kim, A.R., Rylett, R.J., Shilton, B.H.

(2006) Biochemistry 45: 14621-14631

Released	2006-12-12
Method	X-RAY DIFFRACTION 2.27 Å
Organisms	Homo sapiens
Macromolecule	Choline O-acetyltransferase (protein)
Unique Ligands	CHT, GOL

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2HA3 \| pdb_00002ha3	Download File View File

Crystal structure of mouse acetylcholinesterase complexed with choline

Bourne, Y., Radic, Z., Sulzenbacher, G., Kim, E., Taylor, P., Marchot, P.

(2006) J Biological Chem 281: 29256-29267

Released	2006-07-18
Method	X-RAY DIFFRACTION 2.25 Å
Organisms	Mus musculus
Macromolecule	Acetylcholinesterase (protein)
Unique Ligands	CHT, NAG, P6G
Unique branched monosaccharides	FUC, NAG

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2REG \| pdb_00002reg	Download File View File

ABC-transporter choline binding protein in complex with choline

Oswald, C., Schimtt, L., Smits, S.H.J., Hoeing, M., Sohn-Boeser, L., Bremer, E.

(2008) J Biological Chem 283: 32848-32859

Released	2008-09-16
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Rhizobium meliloti (strain 1021)
Macromolecule	PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN (protein)
Unique Ligands	CHT

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2V04 \| pdb_00002v04	Download File View File

CRYSTAL STRUCTURE OF CHOLINE BINDING PROTEIN F FROM STREPTOCOCCUS PNEUMONIAE

Hermoso, J., Molina, R., Kahn, R., Stelter, M.

(2009) EMBO Rep 10: 246

Released	2008-06-10
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Streptococcus pneumoniae R6
Macromolecule	CHOLINE BINDING PROTEIN F (protein)
Unique Ligands	CHT

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2V05 \| pdb_00002v05	Download File View File

CRYSTAL STRUCTURE OF CHOLINE BINDING PROTEIN F FROM STREPTOCOCCUS PNEUMONIAE. CRYSTAL FORM II.

Hermoso, J., Molina, R., Kahn, R., Stelter, M.

To be published

Released	2008-06-10
Method	X-RAY DIFFRACTION 1.67 Å
Organisms	Streptococcus pneumoniae R6
Macromolecule	CHOLINE BINDING PROTEIN F (protein)
Unique Ligands	CHT

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2VYU \| pdb_00002vyu	Download File View File

CRYSTAL STRUCTURE OF CHOLINE BINDING PROTEIN F FROM STREPTOCOCCUS PNEUMONIAE IN THE PRESENCE OF A PEPTIDOGLYCAN ANALOGUE (TETRASACCHARIDE-PENTAPEPTIDE)

Perez-Dorado, I., Molina, R., Hermoso, J.A., Mobashery, S.

(2009) EMBO Rep 10: 246

Released	2009-02-03
Method	X-RAY DIFFRACTION 2.45 Å
Organisms	Streptococcus pneumoniae R6
Macromolecule	CHOLINE BINDING PROTEIN F (protein)
Unique Ligands	CHT

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2WW5 \| pdb_00002ww5	Download File View File

3D-structure of the modular autolysin LytC from Streptococcus pneumoniae at 1.6 A resolution

Perez-Dorado, I., Sanles, R., Hermoso, J.A., Gonzalez, A., Garcia, A., Garcia, P., Garcia, J.L., Menendez, M.

(2010) Nat Struct Mol Biol 17: 576

Released	2010-04-21
Method	X-RAY DIFFRACTION 1.61 Å
Organisms	Streptococcus pneumoniae R6
Macromolecule	1,4-BETA-N-ACETYLMURAMIDASE (protein)
Unique Ligands	CHT, CL, GOL

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2WWC \| pdb_00002wwc	Download File View File

3D-structure of the modular autolysin LytC from Streptococcus pneumoniae in complex with synthetic peptidoglycan ligand

Perez-Dorado, I., Sanles, R., Hermoso, J.A., Gonzalez, A., Garcia, A., Garcia, P., Garcia, J.L.

(2010) Nat Struct Mol Biol 17: 576

Released	2010-04-21
Method	X-RAY DIFFRACTION 1.75 Å
Organisms	Streptococcus pneumoniae R6
Macromolecule	1,4-BETA-N-ACETYLMURAMIDASE (protein)
Unique Ligands	CHT, GOL

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2WWD \| pdb_00002wwd	Download File View File

3D-structure of the modular autolysin LytC from Streptococcus pneumoniae in complex with pneummococcal peptidoglycan fragment

Perez-Dorado, I., Sanles, R., Hermoso, J.A., Gonzalez, A., Garcia, A., Garcia, P., Garcia, J.L.

(2010) Nat Struct Mol Biol 17: 576

Released	2010-04-21
Method	X-RAY DIFFRACTION 2.25 Å
Organisms	Streptococcus pneumoniae R6
Macromolecule	1,4-BETA-N-ACETYLMURAMIDASE (protein)
Unique Ligands	ALA, CHT, GLN, GOL
Unique branched monosaccharides	MUB, NAG

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2X8M \| pdb_00002x8m	Download File View File

Crystal Structure of CbpF in complex with ipratropium by soaking

Silva-Martin, N., Hermoso, J.A.

(2013) Biochim Biophys Acta 1840: 129

Released	2011-04-06
Method	X-RAY DIFFRACTION 1.85 Å
Organisms	Streptococcus pneumoniae R6
Macromolecule	CHOLINE-BINDING PROTEIN F (protein)
Unique Ligands	CHT, GOL, SO4, X8M

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2X8O \| pdb_00002x8o	Download File View File

Crystal Structure of CbpF in complex with Atropine by soaking

Silva-Martin, N., Hermoso, J.A.

To be published

Released	2011-04-06
Method	X-RAY DIFFRACTION 2.03 Å
Organisms	Streptococcus pneumoniae R6
Macromolecule	CHOLINE-BINDING PROTEIN F (protein)
Unique Ligands	CHT, GOL, OIN, SO4

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2X8P \| pdb_00002x8p	Download File View File

Crystal Structure of CbpF in Complex with Atropine by Co- Crystallization

Silva-Martin, N., Hermoso, J.A.

(2013) Biochim Biophys Acta 1840: 129

Released	2011-04-06
Method	X-RAY DIFFRACTION 2.27 Å
Organisms	Streptococcus pneumoniae R6
Macromolecule	CHOLINE-BINDING PROTEIN F (protein)
Unique Ligands	CHT, GOL, OIN, SO4

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3C5I \| pdb_00003c5i	Download File View File

Crystal structure of Plasmodium knowlesi choline kinase, PKH_134520

Wernimont, A.K., Hills, T., Lew, J., Wasney, G., Senesterra, G., Kozieradzki, I., Cossar, D., Vedadi, M., Schapira, M., Bochkarev, A., Arrowsmith, C.H., Bountra, C., Weigelt, J., Edwards, A.M., Hui, R., Artz, J.D., Xiao, T., Structural Genomics Consortium (SGC)

To be published

Released	2008-02-19
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Plasmodium knowlesi
Macromolecule	Choline kinase (protein) Cleaved fragment of N-terminal expression tag (protein)
Unique Ligands	CA, CHT, GOL, MG, UNL

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3P03 \| pdb_00003p03	Download File View File

Crystal structure of BetP-G153D with choline bound

Perez, C., Ressl, S., Ziegler, Z.

(2011) EMBO J 30: 1221-1229

Released	2011-03-30
Method	X-RAY DIFFRACTION 3.35 Å
Organisms	Corynebacterium glutamicum
Macromolecule	Glycine betaine transporter BetP (protein)
Unique Ligands	CHT

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3PPQ \| pdb_00003ppq	Download File View File

Structures of the substrate-binding protein provide insights into the multiple compatible solutes binding specificities of Bacillus subtilis ABC transporter OpuC

Du, Y., Shi, W.W., He, Y.X., Yang, Y.H., Zhou, C.Z., Chen, Y.

(2011) Biochem J 436: 283-289

Released	2011-05-11
Method	X-RAY DIFFRACTION 1.91 Å
Organisms	Bacillus subtilis
Macromolecule	Glycine betaine/carnitine/choline-binding protein (protein)
Unique Ligands	CHT

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3R6U \| pdb_00003r6u	Download File View File

Crystal structure of choline binding protein OpuBC from Bacillus subtilis

Pittelkow, M., Tschapek, B., Smits, S.H.J., Schmitt, L., Bremer, E.

(2011) J Mol Biology 411: 53-67

Released	2011-06-15
Method	X-RAY DIFFRACTION 1.61 Å
Organisms	Bacillus subtilis subsp. subtilis str. JH642
Macromolecule	Choline-binding protein (protein)
Unique Ligands	CHT

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4AGA \| pdb_00004aga	Download File View File

Hofmeister effects of ionic liquids in protein crystallization: direct and water-mediated interactions

Mukhopadhyay, A., Carvalho, A.L., Romao, M.J.

(2012) CrystEngComm 14: 4912

Released	2012-07-18
Method	X-RAY DIFFRACTION 1.5 Å
Organisms	Gallus gallus
Macromolecule	LYSOZYME C (protein)
Unique Ligands	ACT, CHT, CL, NA

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4CNL \| pdb_00004cnl	Download File View File

Crystal structure of the Choline-binding domain of CbpL from Streptococcus pneumoniae

Gutierrez-Fernandez, J., Bartual, S.G., Hermoso, J.A.

(2016) Sci Rep 6: 38094

Released	2015-02-18
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Streptococcus pneumoniae
Macromolecule	PUTATIVE PNEUMOCOCCAL SURFACE PROTEIN (protein)
Unique Ligands	CHT, GOL, SO4

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4DOJ \| pdb_00004doj	Download File View File

Crystal structure of BetP in outward-facing conformation

Perez, C., Ziegler, C.

(2012) Nature 490: 126-130

Released	2012-06-06
Method	X-RAY DIFFRACTION 3.25 Å
Organisms	Corynebacterium glutamicum
Macromolecule	Glycine betaine transporter BetP (protein)
Unique Ligands	CHT, CL, PGT

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4I90 \| pdb_00004i90	Download File View File

Structure of the N254Y/H258Y mutant of the phosphatidylinositol-specific phospholipase C from S. aureus bound to choline

Goldstein, R.I., Cheng, J., Stec, B., Gershenson, A., Roberts, M.F.

(2013) J Biological Chem 288: 14863-14873

Released	2013-04-10
Method	X-RAY DIFFRACTION 1.65 Å
Organisms	Staphylococcus aureus subsp. aureus str. Newman
Macromolecule	1-phosphatidylinositol phosphodiesterase (protein)
Unique Ligands	ACT, CHT, CL

1 to 25 of 68 Structures

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification

1GVM | pdb_00001gvm

1H8G | pdb_00001h8g

1HCX | pdb_00001hcx

1OBA | pdb_00001oba

1P0M | pdb_00001p0m

2FY3 | pdb_00002fy3

2HA3 | pdb_00002ha3

2REG | pdb_00002reg

2V04 | pdb_00002v04

2V05 | pdb_00002v05

2VYU | pdb_00002vyu

2WW5 | pdb_00002ww5

2WWC | pdb_00002wwc

2WWD | pdb_00002wwd

2X8M | pdb_00002x8m

2X8O | pdb_00002x8o

2X8P | pdb_00002x8p

3C5I | pdb_00003c5i

3P03 | pdb_00003p03

3PPQ | pdb_00003ppq

3R6U | pdb_00003r6u

4AGA | pdb_00004aga

4CNL | pdb_00004cnl

4DOJ | pdb_00004doj

4I90 | pdb_00004i90