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234,136 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Citation Author = "Ostrem, J.M."

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Search Summary

This query matches 18 Structures.

Refinements

Structure Determination Methodology

experimental (18)

Scientific Name of Source Organism

	Homo sapiens (17)
	Thermochaetoides thermophila DSM 1495 (1)

Taxonomy

Eukaryota (18)

Experimental Method

X-RAY DIFFRACTION (18)

Polymer Entity Type

Protein (18)

Refinement Resolution (Å)

	1.0 - 1.5 (3)
	1.5 - 2.0 (12)
	2.0 - 2.5 (3)

Release Date

2010 - 2014 (18)

Enzyme Classification Name

Hydrolases (17)

Symmetry Type

	Asymmetric (16)
	Cyclic (3)

SCOP Classification

Alpha and beta proteins (a/b) (17)

AllSelected

1 to 18 of 18 Structures

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Explore in 3D

4L8G \| pdb_00004l8g	Download File View File

Crystal Structure of K-Ras G12C, GDP-bound

Ostrem, J.M., Peters, U., Sos, M.L., Wells, J.A., Shokat, K.M.

(2013) Nature 503: 548-551

Released	2013-11-27
Method	X-RAY DIFFRACTION 1.521 Å
Organisms	Homo sapiens
Macromolecule	GTPase KRas (protein)
Unique Ligands	GDP, MG, NA

Explore in 3D

4L9S \| pdb_00004l9s	Download File View File

Crystal Structure of H-Ras G12C, GDP-bound

Ostrem, J.M., Peters, U., Sos, M.L., Wells, J.A., Shokat, K.M.

(2013) Nature 503: 548-551

Released	2013-11-27
Method	X-RAY DIFFRACTION 1.606 Å
Organisms	Homo sapiens
Macromolecule	GTPase HRas (protein)
Unique Ligands	CA, GDP, MG, NA

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4L9W \| pdb_00004l9w	Download File View File

Crystal Structure of H-Ras G12C, GMPPNP-bound

Ostrem, J.M., Peters, U., Sos, M.L., Wells, J.A., Shokat, K.M.

(2013) Nature 503: 548-551

Released	2013-11-27
Method	X-RAY DIFFRACTION 1.952 Å
Organisms	Homo sapiens
Macromolecule	GTPase HRas (protein)
Unique Ligands	CA, GNP, MG

Explore in 3D

4LPK \| pdb_00004lpk	Download File View File

Crystal Structure of K-Ras WT, GDP-bound

Ostrem, J.M., Peters, U., Sos, M.L., Wells, J.A., Shokat, K.M.

(2013) Nature 503: 548-551

Released	2013-11-27
Method	X-RAY DIFFRACTION 1.5 Å
Organisms	Homo sapiens
Macromolecule	GTPase KRas (protein)
Unique Ligands	CA, GDP, NA

Explore in 3D

4LRW \| pdb_00004lrw	Download File View File

Crystal Structure of K-Ras G12C (cysteine-light), GDP-bound

Ostrem, J.M., Peters, U., Sos, M.L., Wells, J.A., Shokat, K.M.

(2013) Nature 503: 548-551

Released	2013-11-27
Method	X-RAY DIFFRACTION 2.151 Å
Organisms	Homo sapiens
Macromolecule	GTPase KRas (protein)
Unique Ligands	GDP, MG

Explore in 3D

4LUC \| pdb_00004luc	Download File View File

Crystal Structure of small molecule disulfide 6 bound to K-Ras G12C

Ostrem, J.M., Peters, U., Sos, M.L., Wells, J.A., Shokat, K.M.

(2013) Nature 503: 548-551

Released	2013-11-27
Method	X-RAY DIFFRACTION 1.29 Å
Organisms	Homo sapiens
Macromolecule	GTPase KRas (protein)
Unique Ligands	20G, CA, GDP

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4LV6 \| pdb_00004lv6	Download File View File

Crystal Structure of small molecule disulfide 4 covalently bound to K-Ras G12C

Ostrem, J.M., Peters, U., Sos, M.L., Wells, J.A., Shokat, K.M.

(2013) Nature 503: 548-551

Released	2013-11-27
Method	X-RAY DIFFRACTION 1.5 Å
Organisms	Homo sapiens
Macromolecule	GTPase KRas (protein)
Unique Ligands	20H, CA, GDP

Explore in 3D

4LYF \| pdb_00004lyf	Download File View File

Crystal Structure of small molecule vinylsulfonamide 8 covalently bound to K-Ras G12C

Ostrem, J.M., Peters, U., Sos, M.L., Wells, J.A., Shokat, K.M.

(2013) Nature 503: 548-551

Released	2013-11-27
Method	X-RAY DIFFRACTION 1.568 Å
Organisms	Homo sapiens
Macromolecule	GTPase KRas (protein)
Unique Ligands	21C, GDP

Explore in 3D

4LYH \| pdb_00004lyh	Download File View File

Crystal Structure of small molecule vinylsulfonamide 9 covalently bound to K-Ras G12C

Ostrem, J.M., Peters, U., Sos, M.L., Wells, J.A., Shokat, K.M.

(2013) Nature 503: 548-551

Released	2013-11-27
Method	X-RAY DIFFRACTION 1.371 Å
Organisms	Homo sapiens
Macromolecule	GTPase KRas (protein)
Unique Ligands	21F, GDP, SO4

Explore in 3D

4LYJ \| pdb_00004lyj	Download File View File

Crystal Structure of small molecule vinylsulfonamide 9 covalently bound to K-Ras G12C, alternative space group

Ostrem, J.M., Peters, U., Sos, M.L., Wells, J.A., Shokat, K.M.

(2013) Nature 503: 548-551

Released	2013-11-27
Method	X-RAY DIFFRACTION 1.927 Å
Organisms	Homo sapiens
Macromolecule	GTPase KRas (protein)
Unique Ligands	21F, GDP, MG

Explore in 3D

4M1O \| pdb_00004m1o	Download File View File

Crystal Structure of small molecule vinylsulfonamide 7 covalently bound to K-Ras G12C

Ostrem, J.M., Peters, U., Sos, M.L., Wells, J.A., Shokat, K.M.

(2013) Nature 503: 548-551

Released	2013-11-27
Method	X-RAY DIFFRACTION 1.571 Å
Organisms	Homo sapiens
Macromolecule	K-Ras GTPase (protein)
Unique Ligands	21J, GDP

Explore in 3D

4M1S \| pdb_00004m1s	Download File View File

Crystal Structure of small molecule vinylsulfonamide 13 covalently bound to K-Ras G12C

Ostrem, J.M., Peters, U., Sos, M.L., Wells, J.A., Shokat, K.M.

(2013) Nature 503: 548-551

Released	2013-11-27
Method	X-RAY DIFFRACTION 1.552 Å
Organisms	Homo sapiens
Macromolecule	K-Ras GTPase (protein)
Unique Ligands	21K, GDP

Explore in 3D

4M1T \| pdb_00004m1t	Download File View File

Crystal Structure of small molecule vinylsulfonamide 14 covalently bound to K-Ras G12C

Ostrem, J.M., Peters, U., Sos, M.L., Wells, J.A., Shokat, K.M.

(2013) Nature 503: 548-551

Released	2013-11-27
Method	X-RAY DIFFRACTION 1.703 Å
Organisms	Homo sapiens
Macromolecule	K-Ras GTPase (protein)
Unique Ligands	21M, GDP

Explore in 3D

4M1W \| pdb_00004m1w	Download File View File

Crystal Structure of small molecule vinylsulfonamide covalently bound to K-Ras G12C

Ostrem, J.M., Peters, U., Sos, M.L., Wells, J.A., Shokat, K.M.

(2013) Nature 503: 548-551

Released	2013-11-27
Method	X-RAY DIFFRACTION 1.58 Å
Organisms	Homo sapiens
Macromolecule	K-Ras GTPase (protein)
Unique Ligands	21R, GDP, MG

Explore in 3D

4M1Y \| pdb_00004m1y	Download File View File

Crystal Structure of small molecule vinylsulfonamide 15 covalently bound to K-Ras G12C

Ostrem, J.M., Peters, U., Sos, M.L., Wells, J.A., Shokat, K.M.

(2013) Nature 503: 548-551

Released	2013-11-27
Method	X-RAY DIFFRACTION 1.491 Å
Organisms	Homo sapiens
Macromolecule	K-Ras GTPase (protein)
Unique Ligands	21S, GDP

Explore in 3D

4M21 \| pdb_00004m21	Download File View File

Crystal Structure of small molecule acrylamide 11 covalently bound to K-Ras G12C

Ostrem, J.M., Peters, U., Sos, M.L., Wells, J.A., Shokat, K.M.

(2013) Nature 503: 548-551

Released	2013-11-27
Method	X-RAY DIFFRACTION 1.94 Å
Organisms	Homo sapiens
Macromolecule	K-Ras GTPase (protein)
Unique Ligands	21Y, GDP

Explore in 3D

4M22 \| pdb_00004m22	Download File View File

Crystal Structure of small molecule acrylamide 16 covalently bound to K-Ras G12C

Ostrem, J.M., Peters, U., Sos, M.L., Wells, J.A., Shokat, K.M.

(2013) Nature 503: 548-551

Released	2013-11-27
Method	X-RAY DIFFRACTION 2.09 Å
Organisms	Homo sapiens
Macromolecule	K-Ras GTPase (protein)
Unique Ligands	22C, GDP, MG

Explore in 3D

4W7G \| pdb_00004w7g	Download File View File

Crystal Structure of the Dynein Light Intermediate Chain's Conserved Domain

Schroeder, C.M., Ekiert, D.C., Vale, R.D.

(2014) Elife 3: e03351-e03351

Released	2014-10-01
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Thermochaetoides thermophila DSM 1495
Macromolecule	Dynein Light Intermediate Chain (protein)

1 to 18 of 18 Structures

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RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.

4L8G | pdb_00004l8g

Crystal Structure of K-Ras G12C, GDP-bound

4L9S | pdb_00004l9s

Crystal Structure of H-Ras G12C, GDP-bound

4L9W | pdb_00004l9w

Crystal Structure of H-Ras G12C, GMPPNP-bound

4LPK | pdb_00004lpk

Crystal Structure of K-Ras WT, GDP-bound

4LRW | pdb_00004lrw

Crystal Structure of K-Ras G12C (cysteine-light), GDP-bound

4LUC | pdb_00004luc

Crystal Structure of small molecule disulfide 6 bound to K-Ras G12C

4LV6 | pdb_00004lv6

Crystal Structure of small molecule disulfide 4 covalently bound to K-Ras G12C

4LYF | pdb_00004lyf

Crystal Structure of small molecule vinylsulfonamide 8 covalently bound to K-Ras G12C

4LYH | pdb_00004lyh

Crystal Structure of small molecule vinylsulfonamide 9 covalently bound to K-Ras G12C

4LYJ | pdb_00004lyj

Crystal Structure of small molecule vinylsulfonamide 9 covalently bound to K-Ras G12C, alternative space group

4M1O | pdb_00004m1o

Crystal Structure of small molecule vinylsulfonamide 7 covalently bound to K-Ras G12C

4M1S | pdb_00004m1s

Crystal Structure of small molecule vinylsulfonamide 13 covalently bound to K-Ras G12C

4M1T | pdb_00004m1t

Crystal Structure of small molecule vinylsulfonamide 14 covalently bound to K-Ras G12C

4M1W | pdb_00004m1w

Crystal Structure of small molecule vinylsulfonamide covalently bound to K-Ras G12C

4M1Y | pdb_00004m1y

Crystal Structure of small molecule vinylsulfonamide 15 covalently bound to K-Ras G12C

4M21 | pdb_00004m21

Crystal Structure of small molecule acrylamide 11 covalently bound to K-Ras G12C

4M22 | pdb_00004m22

Crystal Structure of small molecule acrylamide 16 covalently bound to K-Ras G12C

4W7G | pdb_00004w7g

Crystal Structure of the Dynein Light Intermediate Chain's Conserved Domain

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type

SCOP Classification

4L8G | pdb_00004l8g

4L9S | pdb_00004l9s

4L9W | pdb_00004l9w

4LPK | pdb_00004lpk

4LRW | pdb_00004lrw

4LUC | pdb_00004luc

4LV6 | pdb_00004lv6

4LYF | pdb_00004lyf

4LYH | pdb_00004lyh

4LYJ | pdb_00004lyj

4M1O | pdb_00004m1o

4M1S | pdb_00004m1s

4M1T | pdb_00004m1t

4M1W | pdb_00004m1w

4M1Y | pdb_00004m1y

4M21 | pdb_00004m21

4M22 | pdb_00004m22

4W7G | pdb_00004w7g