RCSB PDB: Search

2HJQ \| pdb_00002hjq	Download File View File

NMR Structure of Bacillus Subtilis Protein YqbF, Northeast Structural Genomics Target SR449

Ding, K., Ramelot, T.A., Cort, J.R., Wang, D., Janjua, H., Cunningham, K., Ma, L.-C., Xiao, R., Liu, J., Baran, M., Swapna, G.V.T., Acton, T.B., Rost, B., Montelione, G.T., Kennedy, M.A., Northeast Structural Genomics Consortium (NESG)

To be published

Released	2007-06-05
Method	SOLUTION NMR
Organisms	Bacillus subtilis
Macromolecule	Hypothetical protein yqbF (protein)

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2JOE \| pdb_00002joe	Download File View File

NMR Structure of E. Coli YehR Protein. Northeast Structural Genomics Target ER538.

Ding, K., Ramelot, T.A., Cort, J.R., Chen, C.X., Jiang, M., Cunningham, K., Ma, L., Xiao, R., Liu, J., Baran, M.C., Swapna, G.V.T., Acton, T.B., Rost, B., Montelione, G.T., Kennedy, M.A., Northeast Structural Genomics Consortium (NESG)

To be published

Released	2007-04-10
Method	SOLUTION NMR
Organisms	Escherichia coli
Macromolecule	Hypothetical lipoprotein yehR (protein)

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2JOV \| pdb_00002jov	Download File View File

NMR Structure of Clostridium Perfringens Protein CPE0013. Northeast Structural Genomics Target CpR31.

Ding, K., Ramelot, T.A., Anklin, C.G., Wang, H., Nwosu, C., Cunningham, K., Ma, L., Xiao, R., Liu, J., Baran, M.C., Swapna, G.V.T., Acton, T.B., Rost, B., Montelione, G.T., Kennedy, M.A., Northeast Structural Genomics Consortium (NESG)

To be published

Released	2007-05-08
Method	SOLUTION NMR
Organisms	Clostridium perfringens
Macromolecule	Hypothetical protein CPE0013 (protein)

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2JRP \| pdb_00002jrp	Download File View File

Solution NMR Structure of YfgJ from Salmonella typhimurium Modeled with Two Zn+2 Bound, Northeast Structural Genomics Consortium Target StR86

Ding, K., Ramelot, T.A., Cort, J.R., Wang, H., Nwosu, C., Cunningham, K., Owens, L., Ma, L., Xiao, R., Liu, J., Baran, M.C., Swapna, G.V.T., Acton, T.B., Rost, B., Montelione, G.T., Kennedy, M.A., Northeast Structural Genomics Consortium (NESG)

To be published

Released	2007-07-10
Method	SOLUTION NMR
Organisms	Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Macromolecule	Putative cytoplasmic protein (protein)
Unique Ligands	ZN

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2JUZ \| pdb_00002juz	Download File View File

Solution NMR structure of HI0947 from Haemophilus influenzae, Northeast Structural Genomics Consortium Target IR123

Ding, K., Ramelot, T.A., Cort, J.R., Wang, D., Nwosu, C., Owens, L., Xiao, R., Liu, J., Baran, M.C., Swapna, G.V.T., Acton, T.B., Rost, B., Montelione, G.T., Kennedy, M.A., Northeast Structural Genomics Consortium (NESG)

To be published

Released	2007-10-02
Method	SOLUTION NMR
Organisms	Haemophilus influenzae
Macromolecule	UPF0352 protein HI0840 (protein)

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2JZ8 \| pdb_00002jz8	Download File View File

Solution NMR structure of BH09830 from Bartonella henselae modeled with one Zn+2 bound. Northeast Structural Genomics Consortium target BnR55

Ding, K., Cort, J.R., Wang, D., Janjua, H., Owens, L., Xiao, R., Liu, J., Baran, M.C., Swapna, G.V.T., Acton, T.B., Rost, B., Montelione, G.T., Kennedy, M.A., Northeast Structural Genomics Consortium (NESG)

To be published

Released	2008-01-15
Method	SOLUTION NMR
Organisms	Bartonella henselae str. Houston-1
Macromolecule	Uncharacterized protein BH09830 (protein)
Unique Ligands	ZN

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2K75 \| pdb_00002k75	Download File View File

Solution NMR structure of the OB domain of Ta0387 from Thermoplasma acidophilum. Northeast Structural Genomics Consortium target TaR80b.

Ramelot, T.A., Ding, K., Lee, D., Jiang, M., Ciccosanti, C., Xiao, R., Nair, R., Everett, J.K., Swapna, G., Acton, T.B., Rost, B., Montelione, G.T., Kennedy, M.A., Northeast Structural Genomics Consortium (NESG)

To be published

Released	2008-08-19
Method	SOLUTION NMR
Organisms	Thermoplasma acidophilum
Macromolecule	uncharacterized protein Ta0387 (protein)

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2KBN \| pdb_00002kbn	Download File View File

Solution NMR structure of the OB domain (residues 67-166) of MM0293 from Methanosarcina mazei. Northeast Structural Genomics Consortium target MaR214a.

Ramelot, T.A., Ding, K., Magliqui, M., Jiang, M., Ciccosanti, C., Xiao, R., Lui, J., Everett, J.K., Swapna, G., Acton, T.B., Rost, B., Montelione, G.T., Kennedy, M.A., Northeast Structural Genomics Consortium (NESG)

To be published

Released	2009-07-07
Method	SOLUTION NMR
Organisms	Methanosarcina mazei
Macromolecule	Conserved protein (protein)

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2KCD \| pdb_00002kcd	Download File View File

Solution NMR structure of SSP0047 from Staphylococcus saprophyticus. Northeast Structural Genomics Consortium Target SyR6.

Ramelot, T.A., Ding, K., Chen, C.X., Jiang, M., Ciccosanti, C., Xiao, R., Liu, J., Baran, M.C., Swapna, G., Acton, T.B., Rost, B., Montelione, G.T., Kennedy, M.A., Northeast Structural Genomics Consortium (NESG)

To be published

Released	2009-02-10
Method	SOLUTION NMR
Organisms	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 = NCTC 7292
Macromolecule	Uncharacterized protein SSP0047 (protein)

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2KEN \| pdb_00002ken	Download File View File

Solution NMR structure of the OB domain (residues 67-166) of MM0293 from Methanosarcina mazei. Northeast Structural Genomics Consortium target MaR214a.

Ramelot, T.A., Ding, K., Magliqui, M., Jiang, M., Ciccosanti, C., Xiao, R., Lui, J., Everett, J.K., Swapna, G., Acton, T.B., Rost, B., Montelione, G.T., Kennedy, M.A., Northeast Structural Genomics Consortium (NESG)

To be published

Released	2009-02-10
Method	SOLUTION NMR
Organisms	Methanosarcina mazei
Macromolecule	Conserved protein (protein)

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2KF2 \| pdb_00002kf2	Download File View File

Solution NMR structure of of Streptomyces coelicolor polyketide cyclase SCO5315. Northeast Structural Genomics Consortium target RR365

Cort, J.R., Ramelot, T.A., Ding, K., Wang, H., Jiang, M., Maglaqui, M., Xiao, R., Nair, R., Baran, M.C., Everett, J.K., Swapna, G.V.T., Acton, T.B., Rost, B., Montelione, G.T., Kennedy, M.A., Northeast Structural Genomics Consortium (NESG)

To be published

Released	2009-05-19
Method	SOLUTION NMR
Organisms	Streptomyces coelicolor A3(2)
Macromolecule	Putative polyketide cyclase (protein)

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3JB6 \| pdb_00003jb6	Download File View File

In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus

Zhang, X., Ding, K., Yu, X.K., Chang, W., Sun, J.C., Zhou, Z.H.

(2015) Nature 527: 531-534

Released	2015-10-28
Method	ELECTRON MICROSCOPY 3.3 Å
Organisms	Bombyx mori cypovirus 1
Macromolecule	RNA-dependent RNA polymerase (protein) VP1 CSP (protein) Viral structural protein 4 (protein)
Unique Ligands	GTP

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3JB7 \| pdb_00003jb7	Download File View File

In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus

Zhang, X., Ding, K., Yu, X.K., Chang, W., Sun, J.C., Zhou, Z.H.

(2015) Nature 527: 531-534

Released	2015-10-28
Method	ELECTRON MICROSCOPY 4 Å
Organisms	Bombyx mori cypovirus 1
Macromolecule	CPV RNA-dependent RNA polymerase (protein) VP1 CSP (protein) Viral structural protein 4 (protein) RNA (5'-R(PCPCPCPCPC)-3') (nucleic acid) RNA (5'-R(PGPGPGPGPGP*G)-3') (nucleic acid)
Unique Ligands	CTP, GTP

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3TZR \| pdb_00003tzr	Download File View File

Structure of a Riboswitch-like RNA-ligand complex from the Hepatitis C Virus Internal Ribosome Entry Site

Dibrov, S.M., Ding, K., Brunn, N., Parker, M.A., Bergdahl, B.M., Wyles, D.L., Hermann, T.

To be published

Released	2012-03-21
Method	X-RAY DIFFRACTION 2.212 Å
Organisms	Hepacivirus hominis
Macromolecule	5'-R(CPGPAPGPGPAPAPCPUPAPCPUPGPUPCPUPUPCPCPC)-3' (nucleic acid) 5'-R(GPGPUPCPGPUPGPCPAPGPCPCPUPCPGPG)-3' (nucleic acid)
Unique Ligands	MG, SO4, SS0

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4PW2 \| pdb_00004pw2	Download File View File

Crystal structure of D-glucuronyl C5 epimerase

Ke, J., Qin, Y., Gu, X., Brunzelle, J.S., Xu, H.E., Ding, K.

(2015) J Biological Chem 290: 4620-4630

Released	2015-01-14
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Danio rerio
Macromolecule	D-glucuronyl C5 epimerase B (protein)
Unique Ligands	CIT

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4PXQ \| pdb_00004pxq	Download File View File

Crystal structure of D-glucuronyl C5-epimerase in complex with heparin hexasaccharide

Ke, J., Qin, Y., Gu, X., Tan, J., Brunzelle, J.S., Xu, H.E., Ding, K.

(2015) J Biological Chem 290: 4620-4630

Released	2015-01-14
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Danio rerio
Macromolecule	D-glucuronyl C5 epimerase B (protein)
Unique branched monosaccharides	IDS, SGN, UAP

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5FDP \| pdb_00005fdp	Download File View File

Structure of DDR1 receptor tyrosine kinase in complex with D2099 inhibitor at 2.25 Angstroms resolution.

Bartual, S.G., Pinkas, D.M., Wang, Z., Ding, K., Mahajan, P., Kupinska, K., Mukhopadhyay, S., Strain-Damerell, C., Borkowska, O., Talon, R., Kopec, J., Williams, E., Tallant, C., Chaikuad, A., Sorell, F., Newman, J., Burgess-Brown, N., Arrowsmith, C.H., von Delft, F., Edwards, A.M., Bountra, C., Bullock, A., Structural Genomics Consortium (SGC)

(2016) J Med Chem 59: 5911-5916

Released	2016-06-08
Method	X-RAY DIFFRACTION 2.25 Å
Organisms	Homo sapiens
Macromolecule	Epithelial discoidin domain-containing receptor 1 (protein)
Unique Ligands	5WR, EDO, PEG

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5FDX \| pdb_00005fdx	Download File View File

Structure of DDR1 receptor tyrosine kinase in complex with D2164 inhibitor at 2.65 Angstroms resolution.

Bartual, S.G., Pinkas, D.M., Wang, Z., Ding, K., Mahajan, P., Kupinska, K., Mukhopadhyay, S., Strain-Damerell, C., Chalk, R., Borkowska, O., Talon, R., Kopec, J., Williams, E., Tallant, C., Chaikuad, A., Sorell, F., Newman, J., Burgess-Brown, N., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Bullock, A., Structural Genomics Consortium (SGC)

To be published

Released	2016-10-26
Method	X-RAY DIFFRACTION 2.65 Å
Organisms	Homo sapiens
Macromolecule	Epithelial discoidin domain-containing receptor 1 (protein)
Unique Ligands	5X1, EDO, PEG

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5V56 \| pdb_00005v56	Download File View File

2.9A XFEL structure of the multi-domain human smoothened receptor (with E194M mutation) in complex with TC114

Zhang, X., Zhao, F., Wu, Y., Yang, J., Han, G.W., Zhao, S., Ishchenko, A., Ye, L., Lin, X., Ding, K., Dharmarajan, V., Griffin, P.R., Gati, C., Nelson, G., Hunter, M.S., Hanson, M.A., Cherezov, V., Stevens, R.C., Tan, W., Tao, H., Xu, F.

(2017) Nat Commun 8: 15383-15383

Released	2017-05-24
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Homo sapiens Nitratidesulfovibrio vulgaris str. Hildenborough
Macromolecule	Smoothened homolog,Flavodoxin,Smoothened homolog (protein)
Unique Ligands	836, FMN, NAG

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5V57 \| pdb_00005v57	Download File View File

3.0A SYN structure of the multi-domain human smoothened receptor in complex with TC114

Zhang, X., Zhao, F., Wu, Y., Yang, J., Han, G.W., Zhao, S., Ishchenko, A., Ye, L., Lin, X., Ding, K., Dharmarajan, V., Griffin, P.R., Gati, C., Nelson, G., Hunter, M.S., Hanson, M.A., Cherezov, V., Stevens, R.C., Tan, W., Tao, H., Xu, F.

(2017) Nat Commun 8: 15383-15383

Released	2017-05-24
Method	X-RAY DIFFRACTION 3 Å
Organisms	Homo sapiens Nitratidesulfovibrio vulgaris str. Hildenborough
Macromolecule	Smoothened homolog,Flavodoxin,Smoothened homolog (protein)
Unique Ligands	836, FMN, OLC

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5XR8 \| pdb_00005xr8	Download File View File

Crystal structure of the human CB1 in complex with agonist AM841

Hua, T., Vemuri, K., Nikas, P.S., Laprairie, R.B., Wu, Y., Qu, L., Pu, M., Korde, A., Shan, J., Ho, J.H., Han, G.W., Ding, K., Li, X., Liu, H., Hanson, M.A., Zhao, S., Bohn, L.M., Makriyannis, A., Stevens, R.C., Liu, Z.J.

(2017) Nature 547: 468-471

Released	2017-07-12
Method	X-RAY DIFFRACTION 2.95 Å
Organisms	Homo sapiens Nitratidesulfovibrio vulgaris str. Hildenborough
Macromolecule	Cannabinoid receptor 1,Flavodoxin,Cannabinoid receptor 1 (protein)
Unique Ligands	8D0, CLR, FMN, PEG

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5XRA \| pdb_00005xra	Download File View File

Crystal structure of the human CB1 in complex with agonist AM11542

Hua, T., Vemuri, K., Nikas, P.S., Laprairie, R.B., Wu, Y., Qu, L., Pu, M., Korde, A., Shan, J., Ho, J.H., Han, G.W., Ding, K., Li, X., Liu, H., Hanson, M.A., Zhao, S., Bohn, L.M., Makriyannis, A., Stevens, R.C., Liu, Z.J.

(2017) Nature 547: 468-471

Released	2017-07-12
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Homo sapiens Nitratidesulfovibrio vulgaris str. Hildenborough
Macromolecule	Cannabinoid receptor 1,Flavodoxin,Cannabinoid receptor 1 (protein)
Unique Ligands	8D3, CLR, FMN, OLA, OLC, PEG

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6BP7 \| pdb_00006bp7	Download File View File

Recombinant major vault protein [Rattus norvegicus] structure in solution: conformation 2

Ding, K., Zhang, X., Mrazek, J., Kickhoefer, V.A., Lai, M., Ng, H.L., Yang, O.O., Rome, L.H., Zhou, Z.H.

(2018) Structure 26: 619-626.e3

Released	2018-04-04
Method	ELECTRON MICROSCOPY 4.9 Å
Organisms	Rattus norvegicus
Macromolecule	Major vault protein (protein)

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6BP8 \| pdb_00006bp8	Download File View File

Recombinant major vault protein [Rattus norvegicus] structure in solution: conformation 1

Ding, K., Zhang, X., Mrazek, J., Kickhoefer, V.A., Lai, M., Ng, H.L., Yang, O.O., Rome, L.H., Zhou, Z.H.

(2018) Structure 26: 619-626.e3

Released	2018-04-04
Method	ELECTRON MICROSCOPY 4.9 Å
Organisms	Rattus norvegicus
Macromolecule	Major vault protein (protein)

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6BQG \| pdb_00006bqg	Download File View File

Crystal structure of 5-HT2C in complex with ergotamine

Peng, Y., McCorvy, J.D., Harpsoe, K., Lansu, K., Yuan, S., Popov, P., Qu, L., Pu, M., Che, T., Nikolajse, L.F., Huang, X.P., Wu, Y., Shen, L., Bjorn-Yoshimoto, W.E., Ding, K., Wacker, D., Han, G.W., Cheng, J., Katritch, V., Jensen, A.A., Hanson, M.A., Zhao, S., Gloriam, D.E., Roth, B.L., Stevens, R.C., Liu, Z.

(2018) Cell 172: 719-730.e14

Released	2018-02-14
Method	X-RAY DIFFRACTION 3 Å
Organisms	Escherichia coli Homo sapiens
Macromolecule	5-hydroxytryptamine receptor 2C,Soluble cytochrome b562 (protein)
Unique Ligands	ERM, OLC

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification

2HJQ | pdb_00002hjq

2JOE | pdb_00002joe

2JOV | pdb_00002jov

2JRP | pdb_00002jrp

2JUZ | pdb_00002juz

2JZ8 | pdb_00002jz8

2K75 | pdb_00002k75

2KBN | pdb_00002kbn

2KCD | pdb_00002kcd

2KEN | pdb_00002ken

2KF2 | pdb_00002kf2

3JB6 | pdb_00003jb6

3JB7 | pdb_00003jb7

3TZR | pdb_00003tzr

4PW2 | pdb_00004pw2

4PXQ | pdb_00004pxq

5FDP | pdb_00005fdp

5FDX | pdb_00005fdx

5V56 | pdb_00005v56

5V57 | pdb_00005v57

5XR8 | pdb_00005xr8

5XRA | pdb_00005xra

6BP7 | pdb_00006bp7

6BP8 | pdb_00006bp8

6BQG | pdb_00006bqg