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234,136 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Structure Author = "Huang, Z."

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Search Summary

This query matches 19 Structures.

Refinements

Structure Determination Methodology

experimental (19)

Scientific Name of Source Organism

	Escherichia phage T7 (5)
	Pseudomonas aeruginosa (5)
	Pseudomonas aeruginosa UCBPP-PA14 (5)
	Rattus norvegicus (3)
	Triticum aestivum (2)
	Casadabanvirus D3112 (1)
	Escherichia coli (1)
	Hepacivirus hominis (1)
	Homo sapiens (1)
	Pseudomonas phage JBD30 (1)

More...

Taxonomy

	Bacteria (7)
	Duplodnaviria (7)
	Eukaryota (7)
	Riboviria (1)
	other sequences (1)

Experimental Method

	ELECTRON MICROSCOPY (14)
	SOLUTION NMR (3)
	X-RAY DIFFRACTION (2)

Polymer Entity Type

	Protein (18)
	RNA (10)
	DNA (6)

Refinement Resolution (Å)

	2.0 - 2.5 (1)
	2.5 - 3.0 (3)
	3.0 - 3.5 (4)
	3.5 - 4.0 (4)
	4.0 - 4.5 (3)
	> 4.5 (1)

Release Date

	1995 - 1999 (1)
	2000 - 2004 (1)
	2005 - 2009 (1)
	2010 - 2014 (2)
	2015 - 2019 (14)

Enzyme Classification Name

	Hydrolases (10)
	Transferases (6)
	Oxidoreductases (2)

Membrane Protein Annotation

	mpstruc (3)
	MemProtMD (2)
	OPM (2)
	PDBTM (2)

Symmetry Type

	Asymmetric (15)
	Cyclic (3)

SCOP Classification

	Alpha and beta proteins (a+b) (3)
	All beta proteins (1)
	Alpha and beta proteins (a/b) (1)

AllSelected

1 to 19 of 19 Structures

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1A1R \| pdb_00001a1r	Download File View File

HCV NS3 PROTEASE DOMAIN:NS4A PEPTIDE COMPLEX

Kim, J.L., Morgenstern, K.A., Lin, C., Fox, T., Dwyer, M.D., Landro, J.A., Chambers, S.P., Markland, W., Lepre, C.A., O'Malley, E.T., Harbeson, S.L., Rice, C.M., Murcko, M.A., Caron, P.R., Thomson, J.A.

(1996) Cell 87: 343-355

Released	1998-06-17
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Hepacivirus hominis
Macromolecule	NS3 PROTEIN (protein) NS4A PROTEIN (protein)
Unique Ligands	ZN

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1CM8 \| pdb_00001cm8	Download File View File

PHOSPHORYLATED MAP KINASE P38-GAMMA

Bellon, S., Fitzgibbon, M.J., Fox, T., Hsiao, H.M., Wilson, K.P.

(1999) Structure 7: 1057-1065

Released	2000-05-17
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Homo sapiens
Macromolecule	PHOSPHORYLATED MAP KINASE P38-GAMMA (protein)
Unique Ligands	ANP, MG

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2AHT \| pdb_00002aht	Download File View File

Solution structure of domain 6 from the ai5(gamma)group II intron

Erat, M.C., Zerbe, O., Fox, T., Sigel, R.K.O.

(2007) Chembiochem 8: 306-314

Released	2006-10-17
Method	SOLUTION NMR
Organisms	Saccharomyces cerevisiae
Macromolecule	27-MER (nucleic acid)

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2L61 \| pdb_00002l61	Download File View File

Protein and metal cluster structure of the wheat metallothionein domain g-Ec-1. The second part of the puzzle.

Loebus, J., Peroza, E.A., Bluethgen, N., Fox, T., Meyer-Klaucke, W., Zerbe, O., Freisinger, E.

(2011) J Biol Inorg Chem 16: 683-694

Released	2011-05-25
Method	SOLUTION NMR
Organisms	Triticum aestivum
Macromolecule	EC protein I/II (protein)
Unique Ligands	CD

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2L62 \| pdb_00002l62	Download File View File

Protein and metal cluster structure of the wheat metallothionein domain g-Ec-1. The second part of the puzzle.

Loebus, J., Peroza, E.A., Bluethgen, N., Fox, T., Meyer-Klaucke, W., Zerbe, O., Freisinger, E.

(2011) J Biol Inorg Chem 16: 683-694

Released	2011-05-25
Method	SOLUTION NMR
Organisms	Triticum aestivum
Macromolecule	EC protein I/II (protein)
Unique Ligands	ZN

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6B44 \| pdb_00006b44	Download File View File

Cryo-EM structure of Type I-F CRISPR crRNA-guided Csy surveillance complex with bound target dsDNA

Guo, T.W., Bartesaghi, A., Yang, H., Falconieri, V., Rao, P., Merk, A., Fox, T., Earl, L., Patel, D.J., Subramaniam, S.

(2017) Cell 171: 414-426.e12

Released	2017-10-18
Method	ELECTRON MICROSCOPY 2.9 Å
Organisms	Pseudomonas aeruginosa Pseudomonas aeruginosa UCBPP-PA14 synthetic construct
Macromolecule	Unique protein chains: 4 Unique nucleic acid chains: 3

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6B45 \| pdb_00006b45	Download File View File

Cryo-EM structure of Type I-F CRISPR crRNA-guided Csy surveillance complex

Guo, T.W., Bartesaghi, A., Yang, H., Falconieri, V., Rao, P., Merk, A., Fox, T., Earl, L., Patel, D.J., Subramaniam, S.

(2017) Cell 171: 414-426.e12

Released	2017-10-18
Method	ELECTRON MICROSCOPY 3.5 Å
Organisms	Pseudomonas aeruginosa Pseudomonas aeruginosa UCBPP-PA14
Macromolecule	CRISPR-associated endonuclease Cas6/Csy4 (protein) CRISPR-associated protein Csy1 (protein) CRISPR-associated protein Csy2 (protein) CRISPR-associated protein Csy3 (protein) Pseudomonas aeruginosa strain SMC4485 CRISPR repeat sequence (nucleic acid)

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6B46 \| pdb_00006b46	Download File View File

Cryo-EM structure of Type I-F CRISPR crRNA-guided Csy surveillance complex with bound anti-CRISPR protein AcrF1

Guo, T.W., Bartesaghi, A., Yang, H., Falconieri, V., Rao, P., Merk, A., Fox, T., Earl, L., Patel, D.J., Subramaniam, S.

(2017) Cell 171: 414-426.e12

Released	2017-10-18
Method	ELECTRON MICROSCOPY 3.1 Å
Organisms	Pseudomonas aeruginosa Pseudomonas aeruginosa UCBPP-PA14 Pseudomonas phage JBD30
Macromolecule	Anti-CRISPR protein AcrF1 (protein) CRISPR-associated endonuclease Cas6/Csy4 (protein) CRISPR-associated protein Csy3 (protein) Pseudomonas aeruginosa strain SMC4485 CRISPR repeat sequence (nucleic acid)

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6B47 \| pdb_00006b47	Download File View File

Cryo-EM structure of Type I-F CRISPR crRNA-guided Csy surveillance complex with bound anti-CRISPR protein AcrF2

Guo, T.W., Bartesaghi, A., Yang, H., Falconieri, V., Rao, P., Merk, A., Fox, T., Earl, L., Patel, D.J., Subramaniam, S.

(2017) Cell 171: 414-426.e12

Released	2017-10-18
Method	ELECTRON MICROSCOPY 3.2 Å
Organisms	Casadabanvirus D3112 Pseudomonas aeruginosa Pseudomonas aeruginosa UCBPP-PA14
Macromolecule	Unique protein chains: 5 Unique nucleic acid chains: 1

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6B48 \| pdb_00006b48	Download File View File

Cryo-EM structure of Type I-F CRISPR crRNA-guided Csy surveillance complex with bound anti-CRISPR protein AcrF10

Guo, T.W., Bartesaghi, A., Yang, H., Falconieri, V., Rao, P., Merk, A., Fox, T., Earl, L., Patel, D.J., Subramaniam, S.

(2017) Cell 171: 414-426.e12

Released	2017-10-18
Method	ELECTRON MICROSCOPY 3.6 Å
Organisms	Pseudomonas aeruginosa Pseudomonas aeruginosa UCBPP-PA14 Shewanella xiamenensis
Macromolecule	Unique protein chains: 5 Unique nucleic acid chains: 1

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6EBK \| pdb_00006ebk	Download File View File

The voltage-activated Kv1.2-2.1 paddle chimera channel in lipid nanodiscs

Matthies, D., Bae, C., Fox, T., Bartesaghi, A., Subramaniam, S., Swartz, K.J.

(2018) Elife 7:

Released	2018-08-22
Method	ELECTRON MICROSCOPY 3.3 Å
Organisms	Rattus norvegicus
Macromolecule	Potassium voltage-gated channel subfamily A member 2,Potassium voltage-gated channel subfamily B member 2 chimera (protein) Voltage-gated potassium channel subunit beta-2 (protein)
Unique Ligands	NAP

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6EBL \| pdb_00006ebl	Download File View File

The voltage-activated Kv1.2-2.1 paddle chimera channel in lipid nanodiscs, cytosolic domain

Matthies, D., Bae, C., Fox, T., Bartesaghi, A., Subramaniam, S., Swartz, K.J.

(2018) Elife 7:

Released	2018-08-22
Method	ELECTRON MICROSCOPY 3 Å
Organisms	Rattus norvegicus
Macromolecule	Potassium voltage-gated channel subfamily A member 2,Potassium voltage-gated channel subfamily B member 2 chimera (protein) Voltage-gated potassium channel subunit beta-2 (protein)
Unique Ligands	NAP

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6EBM \| pdb_00006ebm	Download File View File

The voltage-activated Kv1.2-2.1 paddle chimera channel in lipid nanodiscs, transmembrane domain of subunit alpha

Matthies, D., Bae, C., Fox, T., Bartesaghi, A., Subramaniam, S., Swartz, K.J.

(2018) Elife 7:

Released	2018-08-22
Method	ELECTRON MICROSCOPY 4 Å
Organisms	Rattus norvegicus
Macromolecule	Potassium voltage-gated channel subfamily A member 2,Potassium voltage-gated channel subfamily B member 2 chimera (protein)

Explore in 3D

6HMA \| pdb_00006hma	Download File View File

Improved model derived from cryo-EM map of Staphylococcus aureus large ribosomal subunit

Eyal, Z., Cimicata, G., Matzov, D., Fox, T., de Val, N., Zimmerman, E., Bashan, A., Yonath, A.

To be published

Released	2018-11-14
Method	ELECTRON MICROSCOPY 2.65 Å
Organisms	Staphylococcus aureus
Macromolecule	Unique protein chains: 27 Unique nucleic acid chains: 2
Unique Ligands	MG

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6N7V \| pdb_00006n7v	Download File View File

Structure of bacteriophage T7 gp4 (helicase-primase, E343Q mutant) in complex with ssDNA, dTTP, AC dinucleotide, and CTP (from multiple lead complexes)

Gao, Y., Fox, T., Val, N., Yang, W.

(2019) Science 363:

Released	2019-03-06
Method	ELECTRON MICROSCOPY 3.8 Å
Organisms	Escherichia phage T7
Macromolecule	DNA primase/helicase (protein) DNA (93-MER) (nucleic acid)
Unique Ligands	MG, TTP

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6N7W \| pdb_00006n7w	Download File View File

Structure of bacteriophage T7 leading-strand DNA polymerase (D5A/E7A)/Trx in complex with a DNA fork and incoming dTTP (from multiple lead complexes)

Gao, Y., Fox, T., Val, N., Yang, W.

(2019) Science 363:

Released	2019-03-06
Method	ELECTRON MICROSCOPY 4.5 Å
Organisms	Escherichia coli Escherichia phage T7
Macromolecule	DNA-directed DNA polymerase (protein) TrxA (protein) DNA (25-MER) (nucleic acid) DNA (77-MER) (nucleic acid)
Unique Ligands	MG, TTP

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6N9U \| pdb_00006n9u	Download File View File

Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) interacting with primase domains of two gp4 subunits bound to an RNA/DNA hybrid and dTTP (from LagS1)

Gao, Y., Fox, T., Val, N., Yang, W.

(2019) Science 363:

Released	2019-03-06
Method	ELECTRON MICROSCOPY 3.7 Å
Organisms	Escherichia phage T7
Macromolecule	DNA primase/helicase (protein) DNA-directed DNA polymerase (protein) DNA (44-MER) (nucleic acid) RNA (5'-R(APCPCPAPG)-D(P(DOC))-3') (nucleic acid)
Unique Ligands	MG, TTP, ZN

Explore in 3D

6N9V \| pdb_00006n9v	Download File View File

Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) and gp4 (helicase/primase) bound to DNA including RNA/DNA hybrid, and an incoming dTTP (LagS1)

Gao, Y., Fox, T., Val, N., Yang, W.

(2019) Science 363:

Released	2019-03-06
Method	ELECTRON MICROSCOPY 4 Å
Organisms	Escherichia phage T7
Macromolecule	DNA primase/helicase (protein) DNA-directed DNA polymerase (protein) Primer (nucleic acid) Template (nucleic acid)
Unique Ligands	MG, TTP, ZN

Explore in 3D

6N9X \| pdb_00006n9x	Download File View File

Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) and gp4 (helicase/primase) bound to DNA including RNA/DNA hybrid, and an incoming dTTP (LagS3)

Gao, Y., Fox, T., Val, N., Yang, W.

(2019) Science 363:

Released	2019-03-06
Method	ELECTRON MICROSCOPY 4.1 Å
Organisms	Escherichia phage T7
Macromolecule	DNA primase/helicase (protein) DNA-directed DNA polymerase (protein) Primer (nucleic acid) Template (nucleic acid)
Unique Ligands	MG, TTP, ZN

1 to 19 of 19 Structures

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RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.

1A1R | pdb_00001a1r

HCV NS3 PROTEASE DOMAIN:NS4A PEPTIDE COMPLEX

1CM8 | pdb_00001cm8

PHOSPHORYLATED MAP KINASE P38-GAMMA

2AHT | pdb_00002aht

Solution structure of domain 6 from the ai5(gamma)group II intron

2L61 | pdb_00002l61

Protein and metal cluster structure of the wheat metallothionein domain g-Ec-1. The second part of the puzzle.

2L62 | pdb_00002l62

Protein and metal cluster structure of the wheat metallothionein domain g-Ec-1. The second part of the puzzle.

6B44 | pdb_00006b44

Cryo-EM structure of Type I-F CRISPR crRNA-guided Csy surveillance complex with bound target dsDNA

6B45 | pdb_00006b45

Cryo-EM structure of Type I-F CRISPR crRNA-guided Csy surveillance complex

6B46 | pdb_00006b46

Cryo-EM structure of Type I-F CRISPR crRNA-guided Csy surveillance complex with bound anti-CRISPR protein AcrF1

6B47 | pdb_00006b47

Cryo-EM structure of Type I-F CRISPR crRNA-guided Csy surveillance complex with bound anti-CRISPR protein AcrF2

6B48 | pdb_00006b48

Cryo-EM structure of Type I-F CRISPR crRNA-guided Csy surveillance complex with bound anti-CRISPR protein AcrF10

6EBK | pdb_00006ebk

The voltage-activated Kv1.2-2.1 paddle chimera channel in lipid nanodiscs

6EBL | pdb_00006ebl

The voltage-activated Kv1.2-2.1 paddle chimera channel in lipid nanodiscs, cytosolic domain

6EBM | pdb_00006ebm

The voltage-activated Kv1.2-2.1 paddle chimera channel in lipid nanodiscs, transmembrane domain of subunit alpha

6HMA | pdb_00006hma

Improved model derived from cryo-EM map of Staphylococcus aureus large ribosomal subunit

6N7V | pdb_00006n7v

Structure of bacteriophage T7 gp4 (helicase-primase, E343Q mutant) in complex with ssDNA, dTTP, AC dinucleotide, and CTP (from multiple lead complexes)

6N7W | pdb_00006n7w

Structure of bacteriophage T7 leading-strand DNA polymerase (D5A/E7A)/Trx in complex with a DNA fork and incoming dTTP (from multiple lead complexes)

6N9U | pdb_00006n9u

Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) interacting with primase domains of two gp4 subunits bound to an RNA/DNA hybrid and dTTP (from LagS1)

6N9V | pdb_00006n9v

Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) and gp4 (helicase/primase) bound to DNA including RNA/DNA hybrid, and an incoming dTTP (LagS1)

6N9X | pdb_00006n9x

Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) and gp4 (helicase/primase) bound to DNA including RNA/DNA hybrid, and an incoming dTTP (LagS3)

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification

1A1R | pdb_00001a1r

1CM8 | pdb_00001cm8

2AHT | pdb_00002aht

2L61 | pdb_00002l61

2L62 | pdb_00002l62

6B44 | pdb_00006b44

6B45 | pdb_00006b45

6B46 | pdb_00006b46

6B47 | pdb_00006b47

6B48 | pdb_00006b48

6EBK | pdb_00006ebk

6EBL | pdb_00006ebl

6EBM | pdb_00006ebm

6HMA | pdb_00006hma

6N7V | pdb_00006n7v

6N7W | pdb_00006n7w

6N9U | pdb_00006n9u

6N9V | pdb_00006n9v

6N9X | pdb_00006n9x