RCSB PDB: Search

1DQS \| pdb_00001dqs	Download File View File

CRYSTAL STRUCTURE OF DEHYDROQUINATE SYNTHASE (DHQS) COMPLEXED WITH CARBAPHOSPHONATE, NAD+ AND ZN2+

Carpenter, E.P., Hawkins, A.R., Frost, J.W., Brown, K.A.

(1998) Nature 394: 299-302

Released	1999-07-26
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Aspergillus nidulans
Macromolecule	PROTEIN (3-DEHYDROQUINATE SYNTHASE) (protein)
Unique Ligands	CL, CRB, NAD, ZN

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2C53 \| pdb_00002c53	Download File View File

A comparative study of uracil DNA glycosylases from human and herpes simplex virus type 1

Krusong, K., Carpenter, E.P., Bellmy, S.R.W., Savva, R., Baldwin, G.S.

(2006) J Biological Chem 281: 4983

Released	2005-11-28
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Human alphaherpesvirus 1
Macromolecule	URACIL DNA GLYCOSYLASE (protein)
Unique Ligands	DUR, GOL

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2C56 \| pdb_00002c56	Download File View File

A comparative study of uracil DNA glycosylases from human and herpes simplex virus type 1

Krusong, K., Carpenter, E.P., Bellamy, S.R.W., Savva, R., Baldwin, G.S.

(2006) J Biological Chem 281: 4983

Released	2005-11-28
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Human alphaherpesvirus 1
Macromolecule	URACIL DNA GLYCOSYLASE (protein)
Unique branched monosaccharides	FRU, GLC

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2D00 \| pdb_00002d00	Download File View File

Subunit F of V-type ATPase/synthase

Makyio, H., Iino, R., Ikeda, C., Imamura, H., Tamakoshi, M., Iwata, M., Stock, D., Bernal, R.A., Carpenter, E.P., Yoshida, M., Yokoyama, K., Iwata, S.

(2005) EMBO J 24: 3974-3983

Released	2005-12-06
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Thermus thermophilus
Macromolecule	V-type ATP synthase subunit F (protein)
Unique Ligands	CA

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2JC4 \| pdb_00002jc4	Download File View File

3'-5' exonuclease (NExo) from Neisseria Meningitidis

Carpenter, E.P., Corbett, A., Thomson, H., Adacha, J., Jensen, K., Bergeron, J., Kasampalidis, I., Exley, R., Winterbotham, M., Tang, C., Baldwin, G., Freemont, P.

(2007) EMBO J 26: 1363

Released	2007-03-06
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Neisseria meningitidis
Macromolecule	EXODEOXYRIBONUCLEASE III (protein)
Unique Ligands	1PE, 2HP, ACT, MG, NA

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2JC5 \| pdb_00002jc5	Download File View File

Apurinic Apyrimidinic (AP) endonuclease (NApe) from Neisseria Meningitidis

Carpenter, E.P., Corbett, A., Thomson, H., Adacha, J., Jensen, K., Bergeron, J., Kasampalidis, I., Exley, R., Winterbotham, M., Tang, C., Baldwin, G.S., Freemont, P.

(2007) EMBO J 26: 1363

Released	2007-03-06
Method	X-RAY DIFFRACTION 1.5 Å
Organisms	Neisseria meningitidis
Macromolecule	EXODEOXYRIBONUCLEASE (protein)
Unique Ligands	BCN, DIO, GOL, MG

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2JH1 \| pdb_00002jh1	Download File View File

Crystal structure of Toxoplasma gondii micronemal protein 1

Blumenschein, T.M.A., Friedrich, N., Childs, R.A., Saouros, S., Carpenter, E.P., Campanero-Rhodes, M.A., Simpson, P., Koutroukides, T., Blackman, M.J., Feizi, T., Soldati-Favre, D., Matthews, S.

(2007) EMBO J 26: 2808

Released	2007-05-22
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Toxoplasma gondii
Macromolecule	MICRONEMAL PROTEIN 1 (protein)
Unique Ligands	ACT, CL, GOL

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2JH7 \| pdb_00002jh7	Download File View File

Crystal structure of Toxoplasma gondii micronemal protein 1 bound to 6'-sialyl-N-acetyllactosamine

Blumenschein, T.M.A., Friedrich, N., Childs, R.A., Saouros, S., Carpenter, E.P., Campanero-Rhodes, M.A., Simpson, P., Koutroukides, T., Blackman, M.J., Feizi, T., Soldati-Favre, D., Matthews, S.

(2007) EMBO J 26: 2808

Released	2007-05-22
Method	X-RAY DIFFRACTION 2.07 Å
Organisms	Toxoplasma gondii
Macromolecule	MICRONEMAL PROTEIN 1 (protein)
Unique Ligands	ACT, CL, GOL
Unique branched monosaccharides	GAL, SIA

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2JHD \| pdb_00002jhd	Download File View File

Crystal structure of Toxoplasma gondii micronemal protein 1 bound to 3'-sialyl-N-acetyllactosamine

Blumenschein, T.M.A., Friedrich, N., Childs, R.A., Saouros, S., Carpenter, E.P., Campanero-Rhodes, M.A., Simpson, P., Koutroukides, T., Blackman, M.J., Feizi, T., Soldati-Favre, D., Matthews, S.

(2007) EMBO J 26: 2808

Released	2007-05-22
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Toxoplasma gondii
Macromolecule	MICRONEMAL PROTEIN 1 (protein)
Unique Ligands	ACT, CL, GOL
Unique branched monosaccharides	GAL, SIA

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2JLN \| pdb_00002jln	Download File View File

Structure of Mhp1, a nucleobase-cation-symport-1 family transporter

Weyand, S., Shimamura, T., Yajima, S., Suzuki, S., Mirza, O., Krusong, K., Carpenter, E.P., Rutherford, N.G., Hadden, J.M., O'Reilly, J., Ma, P., Saidijam, M., Patching, S.G., Hope, R.J., Norbertczak, H.T., Roach, P.C.J., Iwata, S., Henderson, P.J.F., Cameron, A.D.

(2008) Science 322: 709

Released	2008-10-28
Method	X-RAY DIFFRACTION 2.85 Å
Organisms	Microbacterium maritypicum
Macromolecule	MHP1 (protein)
Unique Ligands	HG, NA

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2VOC \| pdb_00002voc	Download File View File

THIOREDOXIN A ACTIVE SITE MUTANTS FORM MIXED DISULFIDE DIMERS THAT RESEMBLE ENZYME-SUBSTRATE REACTION INTERMEDIATE

Kouwen, T.R.H.M., Andrell, J., Schrijver, R., Dubois, J.Y.F., Maher, M.J., Iwata, S., Carpenter, E.P., van Dijl, J.M.

(2008) J Mol Biology 379: 520-534

Released	2009-03-10
Method	X-RAY DIFFRACTION 1.5 Å
Organisms	Bacillus subtilis subsp. subtilis str. 168
Macromolecule	THIOREDOXIN (protein)
Unique Ligands	PEG

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2VYC \| pdb_00002vyc	Download File View File

Crystal Structure of Acid Induced Arginine Decarboxylase from E. coli

Andrell, J., Hicks, M.G., Palmer, T., Carpenter, E.P., Iwata, S., Maher, M.J.

(2009) Biochemistry 48: 3915

Released	2009-03-31
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Escherichia coli BL21(DE3)
Macromolecule	BIODEGRADATIVE ARGININE DECARBOXYLASE (protein)
Unique Ligands	PLP

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2X57 \| pdb_00002x57	Download File View File

Crystal structure of the extracellular domain of human Vasoactive intestinal polypeptide receptor 2

Pike, A.C.W., Barr, A.J., Quigley, A., Burgess Brown, N., de Riso, A., Bullock, A., Berridge, G., Muniz, J.R.C., Chaikaud, A., Vollmar, M., Krojer, T., Ugochukwu, E., von Delft, F., Edwards, A., Arrowsmith, C.H., Weigelt, J., Bountra, C., Carpenter, E.P.

To be published

Released	2010-03-09
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Homo sapiens
Macromolecule	VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 2 (protein)

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2XD7 \| pdb_00002xd7	Download File View File

Crystal structure of the macro domain of human core histone H2A

Vollmar, M., Phillips, C., Carpenter, E.P., Muniz, J.R.C., Krojer, T., Ugochukwu, E., von Delft, F., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., Gileadi, O.

To be published

Released	2010-05-19
Method	X-RAY DIFFRACTION 2.09 Å
Organisms	Homo sapiens
Macromolecule	CORE HISTONE MACRO-H2A.2 (protein)

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2XDG \| pdb_00002xdg	Download File View File

Crystal structure of the extracellular domain of human growth hormone releasing hormone receptor.

Pike, A.C.W., Quigley, A., Barr, A.J., Burgess Brown, N., Shrestha, L., Yang, J., Chaikuad, A., Vollmar, M., Muniz, J.R.C., von Delft, F., Edwards, A., Arrowsmith, C.H., Weigelt, J., Bountra, C., Carpenter, E.P.

To be published

Released	2010-06-16
Method	X-RAY DIFFRACTION 1.95 Å
Organisms	Homo sapiens
Macromolecule	GROWTH HORMONE-RELEASING HORMONE RECEPTOR (protein)
Unique Ligands	EDO, MG

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2XUT \| pdb_00002xut	Download File View File

Crystal structure of a proton dependent oligopeptide (POT) family transporter.

Newstead, S., Drew, D., Cameron, A.D., Postis, V.L., Xia, X., Fowler, P.W., Ingram, J.C., Carpenter, E.P., Sansom, M.S.P., McPherson, M.J., Baldwin, S.A., Iwata, S.

(2011) EMBO J 30: 417

Released	2010-12-15
Method	X-RAY DIFFRACTION 3.62 Å
Organisms	Shewanella oneidensis MR-1
Macromolecule	PROTON/PEPTIDE SYMPORTER FAMILY PROTEIN (protein)

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2XVT \| pdb_00002xvt	Download File View File

Structure of the extracellular domain of human RAMP2

Quigley, A., Pike, A.C.W., Burgess-Brown, N., Krojer, T., Shrestha, L., Goubin, S., Kim, J., Das, S., Muniz, J.R.C., Canning, P., Chaikuad, A., Vollmar, M., von Delft, F., Arrowsmith, C.H., Weigelt, J., Edwards, A.M., Bountra, C., Barr, A.J., Carpenter, E.P.

To be published

Released	2010-12-29
Method	X-RAY DIFFRACTION 2.05 Å
Organisms	Homo sapiens
Macromolecule	RECEPTOR ACTIVITY-MODIFYING PROTEIN 2 (protein)
Unique Ligands	CA

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2YPT \| pdb_00002ypt	Download File View File

Crystal structure of the human nuclear membrane zinc metalloprotease ZMPSTE24 mutant (E336A) in complex with a synthetic CSIM tetrapeptide from the C-terminus of prelamin A

Pike, A.C.W., Dong, Y.Y., Quigley, A., Dong, L., Savitsky, P., Cooper, C.D.O., Chaikuad, A., Goubin, S., Shrestha, L., Li, Q., Mukhopadhyay, S., Yang, J., Xia, X., Shintre, C.A., Barr, A.J., Berridge, G., Chalk, R., Bray, J.E., von Delft, F., Bullock, A., Bountra, C., Arrowsmith, C.H., Edwards, A., Burgess-Brown, N., Carpenter, E.P.

(2013) Science 339: 1604

Released	2012-12-05
Method	X-RAY DIFFRACTION 3.8 Å
Organisms	Homo sapiens
Macromolecule	CAAX PRENYL PROTEASE 1 HOMOLOG (protein) PRELAMIN-A/C (protein)
Unique Ligands	ZN

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3FVQ \| pdb_00003fvq	Download File View File

Crystal structure of the nucleotide binding domain FbpC complexed with ATP

Newstead, S., Bilton, P., Carpenter, E.P., Campopiano, D., Iwata, S.

(2009) Structure 17: 1213-1222

Released	2009-08-25
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Neisseria gonorrhoeae FA 1090
Macromolecule	Fe(3+) ions import ATP-binding protein fbpC (protein)
Unique Ligands	ATP, CA

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3MDZ \| pdb_00003mdz	Download File View File

Crystal Structure of Human Carbonic Anhydrase VII [isoform 1], CA7

Ugochukwu, E., Shafqat, N., Pilka, E., Chaikuad, A., Krojer, T., Muniz, J., Kim, J., Bray, J., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., von Delft, F., Carpenter, E.P., Yue, W.W., Oppermann, U., Structural Genomics Consortium (SGC)

To be published

Released	2010-06-23
Method	X-RAY DIFFRACTION 2.32 Å
Organisms	Homo sapiens
Macromolecule	Carbonic anhydrase 7 (protein)
Unique Ligands	EZL, GOL, ZN

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3ZDQ \| pdb_00003zdq	Download File View File

STRUCTURE OF THE HUMAN MITOCHONDRIAL ABC TRANSPORTER, ABCB10 (NUCLEOTIDE-FREE FORM)

Pike, A.C.W., Shintre, C.A., Krojer, T., von Delft, F., Vollmar, M., Mukhopadhyay, S., Burgess-Brown, N., Arrowsmith, C.H., Bountra, C., Edwards, A.M., Carpenter, E.P.

(2013) Proc Natl Acad Sci U S A 110: 9710

Released	2013-01-23
Method	X-RAY DIFFRACTION 2.85 Å
Organisms	Homo sapiens
Macromolecule	ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, MITOCHONDRIAL (protein)
Unique Ligands	CDL, GLY, LMT

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3ZDU \| pdb_00003zdu	Download File View File

Crystal structure of the human CDKL3 kinase domain

Canning, P., Elkins, J.M., Goubin, S., Mahajan, P., Pike, A.C.W., Quigley, A., MacKenzie, A., Carpenter, E.P., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Bullock, A.

(2018) Cell Rep 22: 885-894

Released	2013-03-20
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Homo sapiens
Macromolecule	CYCLIN-DEPENDENT KINASE-LIKE 3 (protein)
Unique Ligands	38R, EDO, NA, ZN

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4AW6 \| pdb_00004aw6	Download File View File

Crystal structure of the human nuclear membrane zinc metalloprotease ZMPSTE24 (FACE1)

Pike, A.C.W., Dong, Y.Y., Quigley, A., Dong, L., Cooper, C.D.O., Chaikuad, A., Goubin, S., Shrestha, L., Li, Q., Mukhopadhyay, S., Yang, J., Xia, X., Shintre, C.A., Barr, A.J., Berridge, G., Chalk, R., Bray, J.E., von Delft, F., Bullock, A., Bountra, C., Arrowsmith, C.H., Edwards, A., Burgess-Brown, N., Carpenter, E.P.

(2013) Science 339: 1604

Released	2012-07-25
Method	X-RAY DIFFRACTION 3.4 Å
Organisms	Homo sapiens
Macromolecule	CAAX PRENYL PROTEASE 1 HOMOLOG (protein)
Unique Ligands	PC1, ZN

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4AYT \| pdb_00004ayt	Download File View File

STRUCTURE OF THE HUMAN MITOCHONDRIAL ABC TRANSPORTER, ABCB10

Pike, A.C.W., Shintre, C.A., Li, Q., Kim, J., von Delft, F., Barr, A.J., Das, S., Chaikuad, A., Xia, X., Quigley, A., Dong, Y., Dong, L., Krojer, T., Vollmar, M., Muniz, J.R.C., Bray, J.E., Berridge, G., Chalk, R., Gileadi, O., Burgess-Brown, N., Shrestha, L., Goubin, S., Yang, J., Mahajan, P., Mukhopadhyay, S., Bullock, A.N., Arrowsmith, C.H., Weigelt, J., Bountra, C., Edwards, A.M., Carpenter, E.P.

(2013) Proc Natl Acad Sci U S A 110: 9710

Released	2012-07-11
Method	X-RAY DIFFRACTION 2.85 Å
Organisms	Homo sapiens
Macromolecule	ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10 MITOCHONDRIAL (protein)
Unique Ligands	ACP, CDL, GLY, LMT, MG

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4AYW \| pdb_00004ayw	Download File View File

STRUCTURE OF THE HUMAN MITOCHONDRIAL ABC TRANSPORTER, ABCB10 (PLATE FORM)

Pike, A.C.W., Shintre, C.A., Li, Q., Kim, J., von Delft, F., Barr, A.J., Das, S., Chaikuad, A., Xia, X., Quigley, A., Dong, Y., Dong, L., Krojer, T., Vollmar, M., Muniz, J.R.C., Bray, J.E., Berridge, G., Chalk, R., Gileadi, O., Burgess-Brown, N., Shrestha, L., Goubin, S., Yang, J., Mahajan, P., Mukhopadhyay, S., Bullock, A.N., Arrowsmith, C.H., Weigelt, J., Bountra, C., Edwards, A.M., Carpenter, E.P.

(2013) Proc Natl Acad Sci U S A 110: 9710

Released	2012-07-11
Method	X-RAY DIFFRACTION 3.3 Å
Organisms	Homo sapiens
Macromolecule	ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10 (protein)
Unique Ligands	ANP, LMT, Y01

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification

1DQS | pdb_00001dqs

2C53 | pdb_00002c53

2C56 | pdb_00002c56

2D00 | pdb_00002d00

2JC4 | pdb_00002jc4

2JC5 | pdb_00002jc5

2JH1 | pdb_00002jh1

2JH7 | pdb_00002jh7

2JHD | pdb_00002jhd

2JLN | pdb_00002jln

2VOC | pdb_00002voc

2VYC | pdb_00002vyc

2X57 | pdb_00002x57

2XD7 | pdb_00002xd7

2XDG | pdb_00002xdg

2XUT | pdb_00002xut

2XVT | pdb_00002xvt

2YPT | pdb_00002ypt

3FVQ | pdb_00003fvq

3MDZ | pdb_00003mdz

3ZDQ | pdb_00003zdq

3ZDU | pdb_00003zdu

4AW6 | pdb_00004aw6

4AYT | pdb_00004ayt

4AYW | pdb_00004ayw