HTH-type transcriptional regulator MtrR

UniProtKB accession:  P39897

Grouped By:  Matching UniProtKB accession

UniProtKB description:  Controls the permeability of the cell envelope to hydrophobic compounds such as antibiotics and detergents (PubMed:8196548). Represses transcription of the mtrCDE-encoded efflux pump by binding within the mtrCDE promoter (PubMed:23221802, PubMed:9209024). Also negatively regulates the expression of farR, by binding to its promoter region, leading indirectly to the positive regulation of expression of the farAB-encoded efflux pump (PubMed:14645274).