Glutamate dehydrogenase 1, mitochondrial

UniProtKB accession:  P00366

Grouped By:  Matching UniProtKB accession

UniProtKB description:  Mitochondrial glutamate dehydrogenase that converts L-glutamate into alpha-ketoglutarate. Plays a key role in glutamine anaplerosis by producing alpha-ketoglutarate, an important intermediate in the tricarboxylic acid cycle (PubMed:14659072, PubMed:4365183). Plays a role in insulin homeostasis (By similarity). May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate (By similarity).