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Explore in 3D: Sequence Alignments
4EN0_1 - Summary | Structure
Name: Tumor necrosis factor ligand superfamily member 14
Organism: Homo sapiens
Experimental Method: X-ray
Resolution: 2.6 Å
Molecular Weight: 18.433 kDa

Tumor necrosis factor ligand superfamily member 14

UniProtKB accession:  O43557
Grouped By:  Matching UniProtKB accession
Group Content:  
Polymer Entities matching query 8
Go to UniProtKB:  O43557
UniProtKB description:  Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Acts as a ligand for TNFRSF14/HVEM (PubMed:10754304, PubMed:9462508). Upon binding to TNFRSF14/HVEM, delivers costimulatory signals to T cells, leading to T cell proliferation and IFNG production (PubMed:10754304).
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Structure Features
Determination Methodology


Sequence Features
Number of Source Taxonomies


Experimental Features
Experimental Method
Resolution


Organisms
Organism
Taxonomy


Protein Domains
SCOP/SCOPe Domain
ECOD Domain
PFAM Domain
InterPro Domain


Function
GO Molecular Function
GO Biological Process
[ 6+ ]
GO Cellular Component
Disease Association
[ 2+ ]