7RI2
Crystal structure of anti-HIV llama VHH antibody A12 in complex with HIV-1 C1086 gp120
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | GP120_3rd | e7ri2A1 | A: a+b two layers | X: Ribosomal protein L31e-like | H: Ribosomal protein L31e/gp120 outer domain (From Topology) | T: Ribosomal protein L31e/gp120 outer domain | F: GP120_3rd | ECOD (1.6) |
A | GP120_1st | e7ri2A2 | A: a+b two layers | X: gp120 inner domain (From Topology) | H: gp120 inner domain (From Topology) | T: gp120 inner domain | F: GP120_1st | ECOD (1.6) |
B | V-set_12 | e7ri2B1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: V-set_12 | ECOD (1.6) |
SAbDab Antibody Annotation SAbDab Database Homepage
Chain | Chain Class | Chain Subclass | Chain Type | Antigen Name(s) | Provenance Source |
---|---|---|---|---|---|
Heavy Chain | IGHV1 | - | glycoprotein 120 | SAbDab (2024-12-06) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF00516 | Envelope glycoprotein GP120 (GP120) | Envelope glycoprotein GP120 | - | Family | |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR000777 | Human immunodeficiency virus 1, envelope glycoprotein Gp120 | Domain | |
IPR036377 | Gp120 core superfamily | Homologous Superfamily | |
IPR000328 | Retroviral envelope protein GP41-like | Domain | |
IPR037527 | Envelope glycoprotein Gp160 | Family | |
IPR000777 | Human immunodeficiency virus 1, envelope glycoprotein Gp120 | Domain | |
IPR036377 | Gp120 core superfamily | Homologous Superfamily | |
IPR000328 | Retroviral envelope protein GP41-like | Domain | |
IPR037527 | Envelope glycoprotein Gp160 | Family |