Annotations: 7BUG

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d7buga1	All beta proteins	ISP domain	ISP domain	automated matches	automated matches	(Janthinobacterium sp. J3 ) [TaxId: 213804 ],	SCOPe (2.08)
A	d7buga2	Alpha and beta proteins (a+b)	TBP-like	Bet v1-like	Ring hydroxylating alpha subunit catalytic domain	automated matches	(Janthinobacterium sp. J3 ) [TaxId: 213804 ],	SCOPe (2.08)
C	d7bugc1	All beta proteins	ISP domain	ISP domain	automated matches	automated matches	(Janthinobacterium sp. J3 ) [TaxId: 213804 ],	SCOPe (2.08)
C	d7bugc2	Alpha and beta proteins (a+b)	TBP-like	Bet v1-like	Ring hydroxylating alpha subunit catalytic domain	automated matches	(Janthinobacterium sp. J3 ) [TaxId: 213804 ],	SCOPe (2.08)
B	d7bugb1	All beta proteins	ISP domain	ISP domain	automated matches	automated matches	(Janthinobacterium sp. J3 ) [TaxId: 213804 ],	SCOPe (2.08)
B	d7bugb2	Alpha and beta proteins (a+b)	TBP-like	Bet v1-like	Ring hydroxylating alpha subunit catalytic domain	automated matches	(Janthinobacterium sp. J3 ) [TaxId: 213804 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Bet v1-like	8039675	3000738	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	ISP domain	8039674	3000233	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	ISP domain	8039674	3000233	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Bet v1-like	8039675	3000738	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	ISP domain	8039674	3000233	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Bet v1-like	8039675	3000738	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Rieske_8	e7bugA3	A: beta sandwiches	X: ISP domain (From Topology)	H: ISP domain (From Topology)	T: ISP domain	F: Rieske_8	ECOD (1.6)
A	Aromatic_hydrox	e7bugA2	A: a+b two layers	X: TBP-like	H: Bet v1-like (From Topology)	T: Bet v1-like	F: Aromatic_hydrox	ECOD (1.6)
A	Rieske_1	e7bugA1	A: few secondary structure elements	X: Trm112p-like (From Topology)	H: Trm112p-like (From Topology)	T: Trm112p-like	F: Rieske_1	ECOD (1.6)
C	Rieske_8	e7bugC3	A: beta sandwiches	X: ISP domain (From Topology)	H: ISP domain (From Topology)	T: ISP domain	F: Rieske_8	ECOD (1.6)
C	Aromatic_hydrox	e7bugC2	A: a+b two layers	X: TBP-like	H: Bet v1-like (From Topology)	T: Bet v1-like	F: Aromatic_hydrox	ECOD (1.6)
C	Rieske_1	e7bugC1	A: few secondary structure elements	X: Trm112p-like (From Topology)	H: Trm112p-like (From Topology)	T: Trm112p-like	F: Rieske_1	ECOD (1.6)
B	Rieske_8	e7bugB2	A: beta sandwiches	X: ISP domain (From Topology)	H: ISP domain (From Topology)	T: ISP domain	F: Rieske_8	ECOD (1.6)
B	Aromatic_hydrox	e7bugB3	A: a+b two layers	X: TBP-like	H: Bet v1-like (From Topology)	T: Bet v1-like	F: Aromatic_hydrox	ECOD (1.6)
B	Rieske_1	e7bugB1	A: few secondary structure elements	X: Trm112p-like (From Topology)	H: Trm112p-like (From Topology)	T: Trm112p-like	F: Rieske_1	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C	PF11723	Homotrimeric ring hydroxylase (Aromatic_hydrox)	Homotrimeric ring hydroxylase	This domain is found on aromatic hydroxylating enzymes such as 2-oxo-1,2-dihydroquinoline 8-monooxygenase from Pseudomonas putida and carbazole 1,9a-dioxygenase from Janthinobacterium. These enzymes are homotrimers and are distantly related to the ty ...	This domain is found on aromatic hydroxylating enzymes such as 2-oxo-1,2-dihydroquinoline 8-monooxygenase from Pseudomonas putida and carbazole 1,9a-dioxygenase from Janthinobacterium. These enzymes are homotrimers and are distantly related to the typical oxygenase [2]. This domain is found C terminal to the Rieske domain which binds an iron-sulphur cluster.	Domain
A, B, C	PF00355	Rieske [2Fe-2S] domain (Rieske)	Rieske [2Fe-2S] domain	The rieske domain has a [2Fe-2S] centre. Two conserved cysteines coordinate one Fe ion, while the other Fe ion is coordinated by two conserved histidines. In hyperthermophilic archaea there is a SKTPCX(2-3)C motif at the C-terminus. The cysteines in ...	The rieske domain has a [2Fe-2S] centre. Two conserved cysteines coordinate one Fe ion, while the other Fe ion is coordinated by two conserved histidines. In hyperthermophilic archaea there is a SKTPCX(2-3)C motif at the C-terminus. The cysteines in this motif form a disulphide bridge, which stabilises the protein [4].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C	Terminal oxygenase component of carbazole	iron-sulfur cluster binding 2 iron, 2 sulfur cluster binding binding metal cluster binding small molecule binding cation binding ion binding metal ion binding	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C	IPR017941	Rieske [2Fe-2S] iron-sulphur domain	Domain
A, B, C	IPR050584	Cholesterol 7-desaturase	Family
A, B, C	IPR036922	Rieske [2Fe-2S] iron-sulphur domain superfamily	Homologous Superfamily
A, B, C	IPR021028	Homotrimeric ring hydroxylase, catalytic domain	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.