6Z4M
A4V mutant of human SOD1 bound with 2-(pyridin-3-ylmethyl)benzoisoselenazolone derivative 10 in P21 space group
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
A [auth AAA] | SCOP2B Superfamily | Cu, Zn superoxide dismutase-like | 8055253 | 3002059 | SCOP2B (2022-06-29) |
B [auth BBB] | SCOP2B Superfamily | Cu, Zn superoxide dismutase-like | 8055253 | 3002059 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A [auth AAA] | Sod_Cu | e6z4mAAA1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Cu,Zn superoxide dismutase-like | F: Sod_Cu | ECOD (1.6) |
B [auth BBB] | Sod_Cu | e6z4mBBB1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Cu,Zn superoxide dismutase-like | F: Sod_Cu | ECOD (1.6) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
A [auth AAA], B [auth BBB] | PF00080 | Copper/zinc superoxide dismutase (SODC) (Sod_Cu) | Copper/zinc superoxide dismutase (SODC) | superoxide dismutases (SODs) catalyse the conversion of superoxide radicals to hydrogen peroxide and molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the human SOD ... | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Pharos: Disease Associations Pharos Homepage Annotation
Chains | Drug Target | Associated Disease |
---|---|---|
A [auth AAA], B [auth BBB] | P00441 | :