6R76

Crystal structure of trans-3-Hydroxy-L-proline dehydratase from Thermococcus litoralis - open conformation

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Protein Modification Annotation

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d6r76a_	Alpha and beta proteins (a+b)	Diaminopimelate epimerase-like	Diaminopimelate epimerase-like	automated matches	automated matches	(Thermococcus litoralis DSM 5473 ) [TaxId: 523849 ],	SCOPe (2.08)
C	d6r76c_	Alpha and beta proteins (a+b)	Diaminopimelate epimerase-like	Diaminopimelate epimerase-like	automated matches	automated matches	(Thermococcus litoralis DSM 5473 ) [TaxId: 523849 ],	SCOPe (2.08)
B	d6r76b_	Alpha and beta proteins (a+b)	Diaminopimelate epimerase-like	Diaminopimelate epimerase-like	automated matches	automated matches	(Thermococcus litoralis DSM 5473 ) [TaxId: 523849 ],	SCOPe (2.08)
D	d6r76d_	Alpha and beta proteins (a+b)	Diaminopimelate epimerase-like	Diaminopimelate epimerase-like	automated matches	automated matches	(Thermococcus litoralis DSM 5473 ) [TaxId: 523849 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Diaminopimelate epimerase-like	8097874	3000573	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Diaminopimelate epimerase-like	8097874	3000573	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Diaminopimelate epimerase-like	8097874	3000573	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Diaminopimelate epimerase-like	8097874	3000573	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Pro_racemase	e6r76A2	A: a+b complex topology	X: Diaminopimelate epimerase-like (From Topology)	H: Diaminopimelate epimerase-like (From Topology)	T: Diaminopimelate epimerase-like	F: Pro_racemase	ECOD (1.6)
C	Pro_racemase	e6r76C1	A: a+b complex topology	X: Diaminopimelate epimerase-like (From Topology)	H: Diaminopimelate epimerase-like (From Topology)	T: Diaminopimelate epimerase-like	F: Pro_racemase	ECOD (1.6)
B	Pro_racemase	e6r76B1	A: a+b complex topology	X: Diaminopimelate epimerase-like (From Topology)	H: Diaminopimelate epimerase-like (From Topology)	T: Diaminopimelate epimerase-like	F: Pro_racemase	ECOD (1.6)
D	Pro_racemase	e6r76D1	A: a+b complex topology	X: Diaminopimelate epimerase-like (From Topology)	H: Diaminopimelate epimerase-like (From Topology)	T: Diaminopimelate epimerase-like	F: Pro_racemase	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.10.310.10	Alpha Beta	Roll	Diaminopimelate Epimerase	Chain A, domain 1	CATH (utative)
C	3.10.310.10	Alpha Beta	Roll	Diaminopimelate Epimerase	Chain A, domain 1	CATH (utative)
B	3.10.310.10	Alpha Beta	Roll	Diaminopimelate Epimerase	Chain A, domain 1	CATH (utative)
D	3.10.310.10	Alpha Beta	Roll	Diaminopimelate Epimerase	Chain A, domain 1	CATH (utative)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, C	PF05544	Proline racemase (Pro_racemase)	Proline racemase	-	Family
B, D	PF05544	Proline racemase (Pro_racemase)	Proline racemase	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, C	Proline racemase	racemase activity, acting on amino acids and derivatives isomerase activity racemase and epimerase activity racemase and epimerase activity, acting on amino acids and derivatives 4-hydroxyproline epimerase activity amino-acid racemase activity catalytic activity	-	-
B, D	Proline racemase	racemase activity, acting on amino acids and derivatives isomerase activity racemase and epimerase activity racemase and epimerase activity, acting on amino acids and derivatives 4-hydroxyproline epimerase activity amino-acid racemase activity catalytic activity	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, C	IPR008794	Proline racemase family	Family
B, D	IPR008794	Proline racemase family	Family

Protein Modification Annotation

Modified Residue(s)
Chain	Residue(s)	Description
B, D	PHD	Parent Component: ASP RESID: AA0033 PSI-MOD : L-aspartic 4-phosphoric anhydride MOD:00042

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.