6N69
rat hPGDS complexed with a quinoline
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
B | d6n69b2 | All alpha proteins | GST C-terminal domain-like | GST C-terminal domain-like | Glutathione S-transferase (GST), C-terminal domain | Class sigma GST | Rat (Rattus norvegicus ) [TaxId: 10116 ], | SCOPe (2.08) |
B | d6n69b1 | Alpha and beta proteins (a/b) | Thioredoxin fold | Thioredoxin-like | Glutathione S-transferase (GST), N-terminal domain | Class sigma GST | Rat (Rattus norvegicus ) [TaxId: 10116 ], | SCOPe (2.08) |
A | d6n69a2 | All alpha proteins | GST C-terminal domain-like | GST C-terminal domain-like | Glutathione S-transferase (GST), C-terminal domain | Class sigma GST | Rat (Rattus norvegicus ) [TaxId: 10116 ], | SCOPe (2.08) |
A | d6n69a1 | Alpha and beta proteins (a/b) | Thioredoxin fold | Thioredoxin-like | Glutathione S-transferase (GST), N-terminal domain | Class sigma GST | Rat (Rattus norvegicus ) [TaxId: 10116 ], | SCOPe (2.08) |
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
B | SCOP2B Superfamily | Thioredoxin-like | 8044375 | 3000031 | SCOP2B (2022-06-29) |
B | SCOP2B Superfamily | GST C-terminal domain-like | 8037548 | 3000305 | SCOP2B (2022-06-29) |
A | SCOP2B Superfamily | GST C-terminal domain-like | 8037548 | 3000305 | SCOP2B (2022-06-29) |
A | SCOP2B Superfamily | Thioredoxin-like | 8044375 | 3000031 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
B | GST_C_3 | e6n69B2 | A: alpha superhelices | X: Repetitive alpha hairpins | H: Glutathione S-transferase (GST)-C (From Topology) | T: Glutathione S-transferase (GST)-C | F: GST_C_3 | ECOD (1.6) |
B | GST_N_5 | e6n69B1 | A: a+b three layers | X: Thioredoxin-like | H: Thioredoxin-like (From Topology) | T: Thioredoxin-like | F: GST_N_5 | ECOD (1.6) |
A | GST_C_3 | e6n69A2 | A: alpha superhelices | X: Repetitive alpha hairpins | H: Glutathione S-transferase (GST)-C (From Topology) | T: Glutathione S-transferase (GST)-C | F: GST_C_3 | ECOD (1.6) |
A | GST_N_5 | e6n69A1 | A: a+b three layers | X: Thioredoxin-like | H: Thioredoxin-like (From Topology) | T: Thioredoxin-like | F: GST_N_5 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
B | 3.40.30.10 | Alpha Beta | 3-Layer(aba) Sandwich | Glutaredoxin | Glutaredoxin | CATH (utative) |
B | 1.20.1050.10 | Mainly Alpha | Up-down Bundle | Glutathione S-transferase Yfyf (Class Pi) | Chain A, domain 2 | CATH (utative) |
A | 3.40.30.10 | Alpha Beta | 3-Layer(aba) Sandwich | Glutaredoxin | Glutaredoxin | CATH (utative) |
A | 1.20.1050.10 | Mainly Alpha | Up-down Bundle | Glutathione S-transferase Yfyf (Class Pi) | Chain A, domain 2 | CATH (utative) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF14497 | Glutathione S-transferase, C-terminal domain (GST_C_3) | Glutathione S-transferase, C-terminal domain | This domain is closely related to Pfam:PF00043. | Domain | |
PF02798 | Glutathione S-transferase, N-terminal domain (GST_N) | Glutathione S-transferase, N-terminal domain | Function: conjugation of reduced glutathione to a variety of targets. Also included in the alignment, but not GSTs: S-crystallins from squid (similarity to GST previously noted); eukaryotic elongation factors 1-gamma (not known to have GST activity a ... | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR004046 | Glutathione S-transferase, C-terminal | Domain | |
IPR010987 | Glutathione S-transferase, C-terminal-like | Domain | |
IPR004045 | Glutathione S-transferase, N-terminal | Domain | |
IPR050213 | Glutathione S-transferase superfamily | Family | |
IPR036282 | Glutathione S-transferase, C-terminal domain superfamily | Homologous Superfamily | |
IPR036249 | Thioredoxin-like superfamily | Homologous Superfamily | |
IPR040079 | Glutathione transferase family | Family |