5XLO | pdb_00005xlo

Anti-CRISPR proteins AcrF1/2 bound to Csy surveillance complex with a 32nt spacer crRNA backbone region

External Resource: Annotation

Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	UNK_F_TYPE	e5xloA1	A: a+b two layers	X: Alpha-beta plaits	H: Cas7-related	T: CRISPR-associated protein Cas7f/Csy3	F: UNK_F_TYPE	ECOD (1.6)
B	UNK_F_TYPE	e5xloB1	A: a+b two layers	X: Alpha-beta plaits	H: Cas7-related	T: CRISPR-associated protein Cas7f/Csy3	F: UNK_F_TYPE	ECOD (1.6)
C	UNK_F_TYPE	e5xloC1	A: a+b two layers	X: Alpha-beta plaits	H: Cas7-related	T: CRISPR-associated protein Cas7f/Csy3	F: UNK_F_TYPE	ECOD (1.6)
D	UNK_F_TYPE	e5xloD1	A: a+b two layers	X: Alpha-beta plaits	H: Cas7-related	T: CRISPR-associated protein Cas7f/Csy3	F: UNK_F_TYPE	ECOD (1.6)
E	UNK_F_TYPE	e5xloE1	A: a+b two layers	X: Alpha-beta plaits	H: Cas7-related	T: CRISPR-associated protein Cas7f/Csy3	F: UNK_F_TYPE	ECOD (1.6)
F	UNK_F_TYPE	e5xloF1	A: a+b two layers	X: Alpha-beta plaits	H: Cas7-related	T: CRISPR-associated protein Cas7f/Csy3	F: UNK_F_TYPE	ECOD (1.6)
H [auth N]	EUF08659	e5xloN1	A: a+b two layers	X: dsRBD-like	H: Anti-CRISPR protein Acr30-35/AcrF1 (From Topology)	T: Anti-CRISPR protein Acr30-35/AcrF1	F: EUF08659	ECOD (1.6)
I [auth M]	EUF08659	e5xloM1	A: a+b two layers	X: dsRBD-like	H: Anti-CRISPR protein Acr30-35/AcrF1 (From Topology)	T: Anti-CRISPR protein Acr30-35/AcrF1	F: EUF08659	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
H [auth N]	3.30.67.30	Alpha Beta	2-Layer Sandwich	Viral Envelope Glycoprotein	domain 2	CATH (4.3.0)
I [auth M]	3.30.67.30	Alpha Beta	2-Layer Sandwich	Viral Envelope Glycoprotein	domain 2	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
H [auth N], I [auth M]	PF20829	Anti-CRISPR protein Acr30-35/AcrF1 (Acr30-35_AcrF1)	Anti-CRISPR protein Acr30-35/AcrF1	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F	CRISPR-associated protein Csy3	-	biological process involved in interspecies interaction between organisms response to stimulus response to other organism defense response response to external stimulus response to biotic stimulus defense response to virus defense response to other organism response to stress response to external biotic stimulus response to virus	-
G [auth K]	crRNA with 32nt spacer sequence	-	-	-
H [auth N], I [auth M]	Uncharacterized protein AcrF1	-	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F	IPR013399	Type I-F CRISPR-associated protein Csy3	Family
H [auth N], I [auth M]	IPR049088	Anti-CRISPR protein Acr30-35/AcrF1	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.