5Q1R
PanDDA analysis group deposition -- Crystal Structure of DCLRE1A in complex with FMOPL000291a
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | d5q1ra_ | Alpha and beta proteins (a+b) | Metallo-hydrolase/oxidoreductase | Metallo-hydrolase/oxidoreductase | DNA repair metallo-beta-lactamase-like | DNA cross-link repair 1A protein | Human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | Lactamase_B_6_1 | e5q1rA1 | A: a+b four layers | X: Metallo-hydrolase/oxidoreductase (From Topology) | H: Metallo-hydrolase/oxidoreductase (From Topology) | T: Metallo-hydrolase/oxidoreductase | F: Lactamase_B_6_1 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 3.60.15.10 | Alpha Beta | 4-Layer Sandwich | Metallo-beta-lactamase | Chain A | CATH (4.3.0) |
A | 3.40.50.12650 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF07522 | DNA repair metallo-beta-lactamase (DRMBL) | DNA repair metallo-beta-lactamase | The metallo-beta-lactamase fold contains five sequence motifs. The first four motifs are found in Pfam:PF00753 and are common to all metallo-beta-lactamases. The fifth motif appears to be specific to function. This entry represents the fift ... | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR036866 | Ribonuclease Z/Hydroxyacylglutathione hydrolase-like | Homologous Superfamily | |
IPR006642 | Rad18, zinc finger UBZ4-type | Domain | |
IPR011084 | DNA repair metallo-beta-lactamase | Domain |
Pharos: Disease Associations Pharos Homepage Annotation
Chains | Drug Target | Associated Disease |
---|---|---|
Q6PJP8 | :