Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AEUF07937e5jwbA2 A: alpha arraysX: EF-handH: Helical insertion domain in malaria PfNDH2 (From Topology)T: Helical insertion domain in malaria PfNDH2F: EUF07937ECOD (1.6)
AUNK_F_TYPEe5jwbA4 A: a+b two layersX: FAD-linked reductases, C-terminal domain-likeH: FAD/NAD-linked reduatases, dimerisation (C-terminal) domain (From Topology)T: FAD/NAD-linked reduatases, dimerisation (C-terminal) domainF: UNK_F_TYPEECOD (1.6)
APyr_redox_2e5jwbA1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: FAD/NAD(P)-binding domainF: Pyr_redox_2ECOD (1.6)
B [auth H]EUF07937e5jwbH2 A: alpha arraysX: EF-handH: Helical insertion domain in malaria PfNDH2 (From Topology)T: Helical insertion domain in malaria PfNDH2F: EUF07937ECOD (1.6)
B [auth H]UNK_F_TYPEe5jwbH3 A: a+b two layersX: FAD-linked reductases, C-terminal domain-likeH: FAD/NAD-linked reduatases, dimerisation (C-terminal) domain (From Topology)T: FAD/NAD-linked reduatases, dimerisation (C-terminal) domainF: UNK_F_TYPEECOD (1.6)
B [auth H]Pyr_redox_2e5jwbH4 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: FAD/NAD(P)-binding domainF: Pyr_redox_2ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A,
B [auth H]
PF22366NDH2 C-terminal domain (NDH2_C)NDH2 C-terminal domainThis entry represent the C-terminal domain of alternative NADH:quinone oxidoreductases known as NDH2 that deliver electrons to the respiratory chain by oxidation of NADH and reduction of quinones but does not pump protons. NDH-2 have particular relev ...Domain
A,
B [auth H]
PF22365PfNDH2 helical insertion domain (PfNDH2_hel_ins)PfNDH2 helical insertion domainThis entry represent the helical insertion domain of NDH2, a NADH-ubiquinone oxidoreductase from Plasmodium falciparum [1], an interesting target for antimalarial drug development. This domain seems to be present exclusively in Plasmodium sequences.Domain
A,
B [auth H]
PF07992Pyridine nucleotide-disulphide oxidoreductase (Pyr_redox_2)Pyridine nucleotide-disulphide oxidoreductaseThis family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A,
B [auth H]
Type II NADH:ubiquinone oxidoreductase