5A01

O-GlcNAc transferase from Drososphila melanogaster

External Resource: Annotation

Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B	TPR_11_6	e5a01B1	A: alpha superhelices	X: Repetitive alpha hairpins	H: ARM repeat (From Topology)	T: ARM repeat	F: TPR_11_6	ECOD (1.6)
B	Glyco_transf_41_2nd	e5a01B3	A: a+b complex topology	X: Insertion domain in O-GlcNAc transferase (From Topology)	H: Insertion domain in O-GlcNAc transferase (From Topology)	T: Insertion domain in O-GlcNAc transferase	F: Glyco_transf_41_2nd	ECOD (1.6)
B	Glyco_transf_41_1st	e5a01B2	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: Glyco_transf_41_1st	ECOD (1.6)
B	Glyco_transf_41_3rd	e5a01B4	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: Glyco_transf_41_3rd	ECOD (1.6)
A	TPR_11_6	e5a01A3	A: alpha superhelices	X: Repetitive alpha hairpins	H: ARM repeat (From Topology)	T: ARM repeat	F: TPR_11_6	ECOD (1.6)
A	Glyco_transf_41_2nd	e5a01A1	A: a+b complex topology	X: Insertion domain in O-GlcNAc transferase (From Topology)	H: Insertion domain in O-GlcNAc transferase (From Topology)	T: Insertion domain in O-GlcNAc transferase	F: Glyco_transf_41_2nd	ECOD (1.6)
A	Glyco_transf_41_1st	e5a01A4	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: Glyco_transf_41_1st	ECOD (1.6)
A	Glyco_transf_41_3rd	e5a01A2	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: Glyco_transf_41_3rd	ECOD (1.6)
C	TPR_11_6	e5a01C1	A: alpha superhelices	X: Repetitive alpha hairpins	H: ARM repeat (From Topology)	T: ARM repeat	F: TPR_11_6	ECOD (1.6)
C	Glyco_transf_41_2nd	e5a01C4	A: a+b complex topology	X: Insertion domain in O-GlcNAc transferase (From Topology)	H: Insertion domain in O-GlcNAc transferase (From Topology)	T: Insertion domain in O-GlcNAc transferase	F: Glyco_transf_41_2nd	ECOD (1.6)
C	Glyco_transf_41_1st	e5a01C3	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: Glyco_transf_41_1st	ECOD (1.6)
C	Glyco_transf_41_3rd	e5a01C2	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: Glyco_transf_41_3rd	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
B	3.40.50.11380	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold		CATH (4.3.0)
B	3.30.720.150	Alpha Beta	2-Layer Sandwich	Signal recognition particle alu RNA binding heterodimer, srp9/1		CATH (4.3.0)
B	3.40.50.2000	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Glycogen Phosphorylase B	CATH (4.3.0)
A	3.40.50.11380	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold		CATH (4.3.0)
A	3.30.720.150	Alpha Beta	2-Layer Sandwich	Signal recognition particle alu RNA binding heterodimer, srp9/1		CATH (4.3.0)
A	3.40.50.2000	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Glycogen Phosphorylase B	CATH (4.3.0)
C	3.40.50.11380	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold		CATH (4.3.0)
C	3.30.720.150	Alpha Beta	2-Layer Sandwich	Signal recognition particle alu RNA binding heterodimer, srp9/1		CATH (4.3.0)
C	3.40.50.2000	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Glycogen Phosphorylase B	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C	PF13844	Glycosyl transferase family 41 (Glyco_transf_41)	Glycosyl transferase family 41	-	Family
A, B, C	PF13414	TPR repeat (TPR_11)	TPR repeat	-	Repeat

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C	O-GLYCOSYLTRANSFERASE	UDP-glycosyltransferase activity catalytic activity, acting on a protein glycosyltransferase activity protein O-acetylglucosaminyltransferase activity acetylglucosaminyltransferase activity transferase activity hexosyltransferase activity catalytic activity	response to fibroblast growth factor cellular response to stimulus positive regulation of cell communication cellular response to growth factor stimulus regulation of cellular process positive regulation of signal transduction response to stimulus signaling positive regulation of fibroblast growth factor receptor signaling pathway positive regulation of biological process regulation of signal transduction cell surface receptor protein tyrosine kinase signaling pathway cell communication positive regulation of response to stimulus cellular response to endogenous stimulus response to fibroblast growth factor cellular response to stimulus positive regulation of cell communication cellular response to growth factor stimulus regulation of cellular process positive regulation of signal transduction response to stimulus signaling positive regulation of fibroblast growth factor receptor signaling pathway positive regulation of biological process regulation of signal transduction cell surface receptor protein tyrosine kinase signaling pathway cell communication positive regulation of response to stimulus cellular response to endogenous stimulus signal transduction enzyme-linked receptor protein signaling pathway positive regulation of cellular process regulation of biological process regulation of signaling cell surface receptor signaling pathway response to endogenous stimulus regulation of cellular response to growth factor stimulus biological regulation regulation of response to stimulus fibroblast growth factor receptor signaling pathway regulation of cell communication cellular process response to growth factor cellular response to fibroblast growth factor stimulus regulation of fibroblast growth factor receptor signaling pathway positive regulation of signaling regulation of biosynthetic process regulation of macromolecule metabolic process gene expression macromolecule biosynthetic process regulation of gene expression biosynthetic process regulation of macromolecule biosynthetic process metabolic process macromolecule metabolic process regulation of metabolic process carbohydrate derivative biosynthetic process glycoprotein biosynthetic process carbohydrate derivative metabolic process primary metabolic process glycoprotein metabolic process protein glycosylation glycosylation macromolecule modification macromolecule glycosylation protein O-linked glycosylation protein metabolic process protein modification process developmental process imaginal disc development animal organ development anatomical structure development wing disc development behavior rhythmic process multicellular organismal process circadian behavior locomotory behavior rhythmic behavior circadian rhythm locomotor rhythm response to abiotic stimulus response to temperature stimulus	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C	IPR011990	Tetratricopeptide-like helical domain superfamily	Homologous Superfamily
A, B, C	IPR019734	Tetratricopeptide repeat	Repeat
A, B, C	IPR029489	O-GlcNAc transferase, C-terminal	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.