4O1K

Crystal structures of two tetrameric beta-carbonic anhydrases from the filamentous ascomycete Sordaria macrospora.

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d4o1ka_	Alpha and beta proteins (a/b)	Resolvase-like	beta-carbonic anhydrase, cab	automated matches	automated matches	(Sordaria macrospora ) [TaxId: 5147 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	beta-carbonic anhydrase, cab	8082600	4000510	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	beta-carbonic anhydrase, cab	8082601	3000468	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Pro_CA	e4o1kA1	A: a/b three-layered sandwiches	X: beta-carbonic anhydrase-like	H: beta-carbonic anhydrase (From Topology)	T: beta-carbonic anhydrase	F: Pro_CA	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.1050.10	Alpha Beta	3-Layer(aba) Sandwich	Beta-carbonic Anhydrase	Chain A	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF00484	Carbonic anhydrase (Pro_CA)	Carbonic anhydrase	This family includes carbonic anhydrases as well as a family of non-functional homologues related to YbcF.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Carbonic anhydrase	cation binding transition metal ion binding zinc ion binding ion binding binding metal ion binding small molecule binding carbonate dehydratase activity hydro-lyase activity lyase activity catalytic activity carbon-oxygen lyase activity	carbon utilization response to nutrient levels response to stimulus cellular response to stimulus cellular response to chemical stimulus cellular response to carbon dioxide response to chemical response to oxygen-containing compound cellular process cellular response to oxygen-containing compound response to carbon dioxide response to oxidative stress cellular response to stress response to stress carbon utilization response to nutrient levels response to stimulus cellular response to stimulus cellular response to chemical stimulus cellular response to carbon dioxide response to chemical response to oxygen-containing compound cellular process cellular response to oxygen-containing compound response to carbon dioxide response to oxidative stress cellular response to stress response to stress cellular response to oxidative stress cellular response to chemical stress	cellular anatomical structure intracellular anatomical structure cytoplasm

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR001765	Carbonic anhydrase	Family
A	IPR015892	Carbonic anhydrase, prokaryotic-like, conserved site	Conserved Site
A	IPR036874	Carbonic anhydrase superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.