4BWD | pdb_00004bwd

Human short coiled coil protein

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: CATH
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Pharos: Disease Associations

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Short coiled coil protein (SCOC) -like	8051689	4007473	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Short coiled coil protein (SCOC) -like	8102522	3002732	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	Short coiled coil protein (SCOC) -like	8102522	3002732	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Short coiled coil protein (SCOC) -like	8102522	3002732	SCOP2B (2022-06-29)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
B	1.20.5.170	Mainly Alpha	Up-down Bundle	Single alpha-helices involved in coiled-coils or other helix-helix interfaces		CATH (4.3.0)
C	1.20.5.170	Mainly Alpha	Up-down Bundle	Single alpha-helices involved in coiled-coils or other helix-helix interfaces		CATH (4.3.0)

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C	SHORT COILED-COIL PROTEIN	-	positive regulation of autophagy regulation of biological process catabolic process regulation of cellular process macroautophagy autophagy biological regulation positive regulation of biological process regulation of catabolic process regulation of autophagy positive regulation of catabolic process positive regulation of metabolic process regulation of macroautophagy cellular process positive regulation of autophagy regulation of biological process catabolic process regulation of cellular process macroautophagy autophagy biological regulation positive regulation of biological process regulation of catabolic process regulation of autophagy positive regulation of catabolic process positive regulation of metabolic process regulation of macroautophagy cellular process metabolic process positive regulation of macroautophagy process utilizing autophagic mechanism regulation of metabolic process positive regulation of cellular process regulation of protein complex stability regulation of biological quality	cellular anatomical structure intracellular anatomical structure cytoplasm cytosol membrane-bounded organelle intracellular organelle Golgi apparatus organelle intracellular membrane-bounded organelle endomembrane system Golgi membrane membrane bounding membrane of organelle organelle membrane cellular anatomical structure intracellular anatomical structure cytoplasm cytosol membrane-bounded organelle intracellular organelle Golgi apparatus organelle intracellular membrane-bounded organelle endomembrane system Golgi membrane membrane bounding membrane of organelle organelle membrane nucleus membrane-enclosed lumen intracellular organelle lumen nucleoplasm organelle lumen nuclear lumen

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C	IPR019357	Short coiled-coil protein	Family

Pharos: Disease Associations Pharos Homepage Annotation

Chains	Drug Target	Associated Disease
A, B, C	Pharos: Q9UIL1	Alzheimer disease glioblastoma large cell medulloblastoma ovarian cancer attention deficit hyperactivity disorder, inattentive type hereditary spastic paraplegia lung carcinoma Pick disease breast cancer invasive ductal breast carcinoma osteosarcoma

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.