3JQM

Binding of 5'-GTP to molybdenum cofactor biosynthesis protein MoaC from Thermus theromophilus HB8

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d3jqma_	Alpha and beta proteins (a+b)	Ferredoxin-like	Molybdenum cofactor biosynthesis protein C, MoaC	automated matches	automated matches	(Thermus thermophilus HB8 ) [TaxId: 300852 ],	SCOPe (2.08)
B	d3jqmb_	Alpha and beta proteins (a+b)	Ferredoxin-like	Molybdenum cofactor biosynthesis protein C, MoaC	automated matches	automated matches	(Thermus thermophilus HB8 ) [TaxId: 300852 ],	SCOPe (2.08)
C	d3jqmc_	Alpha and beta proteins (a+b)	Ferredoxin-like	Molybdenum cofactor biosynthesis protein C, MoaC	automated matches	automated matches	(Thermus thermophilus HB8 ) [TaxId: 300852 ],	SCOPe (2.08)
E	d3jqme_	Alpha and beta proteins (a+b)	Ferredoxin-like	Molybdenum cofactor biosynthesis protein C, MoaC	automated matches	automated matches	(Thermus thermophilus HB8 ) [TaxId: 300852 ],	SCOPe (2.08)
H	d3jqmh_	Alpha and beta proteins (a+b)	Ferredoxin-like	Molybdenum cofactor biosynthesis protein C, MoaC	automated matches	automated matches	(Thermus thermophilus HB8 ) [TaxId: 300852 ],	SCOPe (2.08)
I	d3jqmi_	Alpha and beta proteins (a+b)	Ferredoxin-like	Molybdenum cofactor biosynthesis protein C, MoaC	automated matches	automated matches	(Thermus thermophilus HB8 ) [TaxId: 300852 ],	SCOPe (2.08)
D	d3jqmd_	Alpha and beta proteins (a+b)	Ferredoxin-like	Molybdenum cofactor biosynthesis protein C, MoaC	automated matches	automated matches	(Thermus thermophilus HB8 ) [TaxId: 300852 ],	SCOPe (2.08)
F	d3jqmf_	Alpha and beta proteins (a+b)	Ferredoxin-like	Molybdenum cofactor biosynthesis protein C, MoaC	automated matches	automated matches	(Thermus thermophilus HB8 ) [TaxId: 300852 ],	SCOPe (2.08)
G	d3jqmg_	Alpha and beta proteins (a+b)	Ferredoxin-like	Molybdenum cofactor biosynthesis protein C, MoaC	automated matches	automated matches	(Thermus thermophilus HB8 ) [TaxId: 300852 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Molybdenum cofactor biosynthesis protein C, MoaC	8074838	3001204	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Molybdenum cofactor biosynthesis protein C, MoaC	8074838	3001204	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Molybdenum cofactor biosynthesis protein C, MoaC	8074838	3001204	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	Molybdenum cofactor biosynthesis protein C, MoaC	8074838	3001204	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	Molybdenum cofactor biosynthesis protein C, MoaC	8074838	3001204	SCOP2B (2022-06-29)
I	SCOP2B Superfamily	Molybdenum cofactor biosynthesis protein C, MoaC	8074838	3001204	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Molybdenum cofactor biosynthesis protein C, MoaC	8074838	3001204	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	Molybdenum cofactor biosynthesis protein C, MoaC	8074838	3001204	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	Molybdenum cofactor biosynthesis protein C, MoaC	8074838	3001204	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	MoaC	e3jqmA1	A: a+b two layers	X: Alpha-beta plaits	H: Molybdenum cofactor biosynthesis protein C, MoaC (From Topology)	T: Molybdenum cofactor biosynthesis protein C, MoaC	F: MoaC	ECOD (1.6)
B	MoaC	e3jqmB1	A: a+b two layers	X: Alpha-beta plaits	H: Molybdenum cofactor biosynthesis protein C, MoaC (From Topology)	T: Molybdenum cofactor biosynthesis protein C, MoaC	F: MoaC	ECOD (1.6)
C	MoaC	e3jqmC1	A: a+b two layers	X: Alpha-beta plaits	H: Molybdenum cofactor biosynthesis protein C, MoaC (From Topology)	T: Molybdenum cofactor biosynthesis protein C, MoaC	F: MoaC	ECOD (1.6)
E	MoaC	e3jqmE1	A: a+b two layers	X: Alpha-beta plaits	H: Molybdenum cofactor biosynthesis protein C, MoaC (From Topology)	T: Molybdenum cofactor biosynthesis protein C, MoaC	F: MoaC	ECOD (1.6)
H	MoaC	e3jqmH1	A: a+b two layers	X: Alpha-beta plaits	H: Molybdenum cofactor biosynthesis protein C, MoaC (From Topology)	T: Molybdenum cofactor biosynthesis protein C, MoaC	F: MoaC	ECOD (1.6)
I	MoaC	e3jqmI1	A: a+b two layers	X: Alpha-beta plaits	H: Molybdenum cofactor biosynthesis protein C, MoaC (From Topology)	T: Molybdenum cofactor biosynthesis protein C, MoaC	F: MoaC	ECOD (1.6)
D	MoaC	e3jqmD1	A: a+b two layers	X: Alpha-beta plaits	H: Molybdenum cofactor biosynthesis protein C, MoaC (From Topology)	T: Molybdenum cofactor biosynthesis protein C, MoaC	F: MoaC	ECOD (1.6)
F	MoaC	e3jqmF1	A: a+b two layers	X: Alpha-beta plaits	H: Molybdenum cofactor biosynthesis protein C, MoaC (From Topology)	T: Molybdenum cofactor biosynthesis protein C, MoaC	F: MoaC	ECOD (1.6)
G	MoaC	e3jqmG1	A: a+b two layers	X: Alpha-beta plaits	H: Molybdenum cofactor biosynthesis protein C, MoaC (From Topology)	T: Molybdenum cofactor biosynthesis protein C, MoaC	F: MoaC	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.30.70.640	Alpha Beta	2-Layer Sandwich	Alpha-Beta Plaits	Molybdopterin cofactor biosynthesis C (MoaC) domain	CATH (4.3.0)
B	3.30.70.640	Alpha Beta	2-Layer Sandwich	Alpha-Beta Plaits	Molybdopterin cofactor biosynthesis C (MoaC) domain	CATH (4.3.0)
C	3.30.70.640	Alpha Beta	2-Layer Sandwich	Alpha-Beta Plaits	Molybdopterin cofactor biosynthesis C (MoaC) domain	CATH (4.3.0)
E	3.30.70.640	Alpha Beta	2-Layer Sandwich	Alpha-Beta Plaits	Molybdopterin cofactor biosynthesis C (MoaC) domain	CATH (4.3.0)
H	3.30.70.640	Alpha Beta	2-Layer Sandwich	Alpha-Beta Plaits	Molybdopterin cofactor biosynthesis C (MoaC) domain	CATH (4.3.0)
I	3.30.70.640	Alpha Beta	2-Layer Sandwich	Alpha-Beta Plaits	Molybdopterin cofactor biosynthesis C (MoaC) domain	CATH (4.3.0)
D	3.30.70.640	Alpha Beta	2-Layer Sandwich	Alpha-Beta Plaits	Molybdopterin cofactor biosynthesis C (MoaC) domain	CATH (4.3.0)
F	3.30.70.640	Alpha Beta	2-Layer Sandwich	Alpha-Beta Plaits	Molybdopterin cofactor biosynthesis C (MoaC) domain	CATH (4.3.0)
G	3.30.70.640	Alpha Beta	2-Layer Sandwich	Alpha-Beta Plaits	Molybdopterin cofactor biosynthesis C (MoaC) domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F, G, H, I	PF01967	MoaC family (MoaC)	MoaC family	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G, H, I	Molybdenum cofactor biosynthesis protein C	phosphorus-oxygen lyase activity lyase activity catalytic activity cyclic pyranopterin monophosphate synthase activity binding guanyl nucleotide binding GTP binding nucleotide binding guanyl ribonucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding organic cyclic compound binding phosphorus-oxygen lyase activity lyase activity catalytic activity cyclic pyranopterin monophosphate synthase activity binding guanyl nucleotide binding GTP binding nucleotide binding guanyl ribonucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding organic cyclic compound binding purine nucleotide binding anion binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding	Mo-molybdopterin cofactor biosynthetic process Mo-molybdopterin cofactor metabolic process primary metabolic process prosthetic group metabolic process molybdopterin cofactor biosynthetic process biosynthetic process organophosphate metabolic process organophosphate biosynthetic process molybdopterin cofactor metabolic process phosphate-containing compound metabolic process metabolic process cellular process protein metabolic process macromolecule metabolic process Mo-molybdopterin cofactor biosynthetic process Mo-molybdopterin cofactor metabolic process primary metabolic process prosthetic group metabolic process molybdopterin cofactor biosynthetic process biosynthetic process organophosphate metabolic process organophosphate biosynthetic process molybdopterin cofactor metabolic process phosphate-containing compound metabolic process metabolic process cellular process protein metabolic process macromolecule metabolic process phosphorus metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G, H, I	IPR023045	Molybdenum cofactor biosynthesis C	Family
A, B, C, D, E A, B, C, D, E, F, G, H, I	IPR002820	Molybdopterin cofactor biosynthesis C (MoaC) domain	Domain
A, B, C, D, E A, B, C, D, E, F, G, H, I	IPR047594	Molybdenum cofactor biosynthesis C, bacteria/eukaryotes	Family
A, B, C, D, E A, B, C, D, E, F, G, H, I	IPR036522	Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.