3D1K

R/T intermediate quaternary structure of an antarctic fish hemoglobin in an alpha(CO)-beta(pentacoordinate) state

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
B	d3d1kb_	All alpha proteins	Globin-like	Globin-like	Globins	Hemoglobin, beta-chain	(Trematomus newnesi ) [TaxId: 35730 ],	SCOPe (2.08)
A	d3d1ka_	All alpha proteins	Globin-like	Globin-like	Globins	Hemoglobin, alpha-chain	(Trematomus newnesi ) [TaxId: 35730 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
B	SCOP2 Family	Globins	8028021	4000551	SCOP2 (2022-06-29)
B	SCOP2 Superfamily	Globin-like	8040400	3000554	SCOP2 (2022-06-29)
A	SCOP2 Family	Globins	8028019	4000551	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Globin-like	8040398	3000554	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B	Globin	e3d1kB1	A: alpha arrays	X: Globin-like (From Topology)	H: Globin-like (From Topology)	T: Globin-like	F: Globin	ECOD (1.6)
A	Globin	e3d1kA1	A: alpha arrays	X: Globin-like (From Topology)	H: Globin-like (From Topology)	T: Globin-like	F: Globin	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
B	1.10.490.10	Mainly Alpha	Orthogonal Bundle	Globin-like	Globins	CATH (4.3.0)
A	1.10.490.10	Mainly Alpha	Orthogonal Bundle	Globin-like	Globins	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
B	PF00042	Globin (Globin)	Globin	-	Domain
A	PF00042	Globin (Globin)	Globin	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
B	Hemoglobin subunit beta-1/2	protein binding binding haptoglobin binding oxygen binding small molecule binding oxygen carrier activity molecular carrier activity peroxidase activity oxidoreductase activity antioxidant activity oxidoreductase activity, acting on peroxide as acceptor catalytic activity organic cyclic compound binding tetrapyrrole binding protein binding binding haptoglobin binding oxygen binding small molecule binding oxygen carrier activity molecular carrier activity peroxidase activity oxidoreductase activity antioxidant activity oxidoreductase activity, acting on peroxide as acceptor catalytic activity organic cyclic compound binding tetrapyrrole binding heme binding organic acid binding cation binding ion binding metal ion binding	catabolic process hydrogen peroxide metabolic process reactive oxygen species metabolic process metabolic process cellular process hydrogen peroxide catabolic process	protein-containing complex cellular anatomical structure intracellular anatomical structure hemoglobin complex cytoplasm cytosol haptoglobin-hemoglobin complex extracellular region extracellular space blood microparticle
A	Hemoglobin subunit alpha-1	protein binding binding haptoglobin binding oxygen binding small molecule binding oxygen carrier activity molecular carrier activity peroxidase activity oxidoreductase activity antioxidant activity oxidoreductase activity, acting on peroxide as acceptor catalytic activity organic cyclic compound binding tetrapyrrole binding protein binding binding haptoglobin binding oxygen binding small molecule binding oxygen carrier activity molecular carrier activity peroxidase activity oxidoreductase activity antioxidant activity oxidoreductase activity, acting on peroxide as acceptor catalytic activity organic cyclic compound binding tetrapyrrole binding heme binding cation binding transition metal ion binding iron ion binding ion binding metal ion binding organic acid binding	catabolic process hydrogen peroxide metabolic process reactive oxygen species metabolic process metabolic process cellular process hydrogen peroxide catabolic process	protein-containing complex cellular anatomical structure intracellular anatomical structure hemoglobin complex cytoplasm cytosol haptoglobin-hemoglobin complex extracellular region extracellular space blood microparticle

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
B	IPR050056	Hemoglobin and related oxygen transporters	Family
B	IPR009050	Globin-like superfamily	Homologous Superfamily
B	IPR012292	Globin/Protoglobin	Homologous Superfamily
B	IPR002337	Hemoglobin, beta-type	Family
B	IPR000971	Globin	Domain
A	IPR050056	Hemoglobin and related oxygen transporters	Family
A	IPR002338	Hemoglobin, alpha-type	Family
A	IPR002339	Hemoglobin, pi	Family
A	IPR009050	Globin-like superfamily	Homologous Superfamily
A	IPR012292	Globin/Protoglobin	Homologous Superfamily
A	IPR000971	Globin	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.