Annotations: 2RB9

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	AIRS_C	e2rb9A1	A: a+b two layers	X: Alpha-beta plaits	H: PurM C-terminal domain-like (From Topology)	T: PurM C-terminal domain-like	F: AIRS_C	ECOD (1.6)
A	AIRS	e2rb9A2	A: a+b three layers	X: Bacillus chorismate mutase-like	H: PurM N-terminal domain-like (From Topology)	T: PurM N-terminal domain-like	F: AIRS	ECOD (1.6)
B	AIRS_C	e2rb9B1	A: a+b two layers	X: Alpha-beta plaits	H: PurM C-terminal domain-like (From Topology)	T: PurM C-terminal domain-like	F: AIRS_C	ECOD (1.6)
B	AIRS	e2rb9B2	A: a+b three layers	X: Bacillus chorismate mutase-like	H: PurM N-terminal domain-like (From Topology)	T: PurM N-terminal domain-like	F: AIRS	ECOD (1.6)
C	AIRS_C	e2rb9C1	A: a+b two layers	X: Alpha-beta plaits	H: PurM C-terminal domain-like (From Topology)	T: PurM C-terminal domain-like	F: AIRS_C	ECOD (1.6)
C	AIRS	e2rb9C2	A: a+b three layers	X: Bacillus chorismate mutase-like	H: PurM N-terminal domain-like (From Topology)	T: PurM N-terminal domain-like	F: AIRS	ECOD (1.6)
D	AIRS_C	e2rb9D1	A: a+b two layers	X: Alpha-beta plaits	H: PurM C-terminal domain-like (From Topology)	T: PurM C-terminal domain-like	F: AIRS_C	ECOD (1.6)
D	AIRS	e2rb9D2	A: a+b three layers	X: Bacillus chorismate mutase-like	H: PurM N-terminal domain-like (From Topology)	T: PurM N-terminal domain-like	F: AIRS	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.30.1330.10	Alpha Beta	2-Layer Sandwich	60s Ribosomal Protein L30	Chain: A	CATH (4.3.0)
A	3.90.650.10	Alpha Beta	Alpha-Beta Complex	Phosphoribosyl-aminoimidazole Synthetase	Chain A, domain 2	CATH (4.3.0)
B	3.30.1330.10	Alpha Beta	2-Layer Sandwich	60s Ribosomal Protein L30	Chain: A	CATH (4.3.0)
B	3.90.650.10	Alpha Beta	Alpha-Beta Complex	Phosphoribosyl-aminoimidazole Synthetase	Chain A, domain 2	CATH (4.3.0)
C	3.30.1330.10	Alpha Beta	2-Layer Sandwich	60s Ribosomal Protein L30	Chain: A	CATH (4.3.0)
C	3.90.650.10	Alpha Beta	Alpha-Beta Complex	Phosphoribosyl-aminoimidazole Synthetase	Chain A, domain 2	CATH (4.3.0)
D	3.30.1330.10	Alpha Beta	2-Layer Sandwich	60s Ribosomal Protein L30	Chain: A	CATH (4.3.0)
D	3.90.650.10	Alpha Beta	Alpha-Beta Complex	Phosphoribosyl-aminoimidazole Synthetase	Chain A, domain 2	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF02769	AIR synthase related protein, C-terminal domain (AIRS_C)	AIR synthase related protein, C-terminal domain	This family includes Hydrogen expression/formation protein HypE Swiss:P24193, AIR synthases Swiss:P08178 EC:6.3.3.1, FGAM synthase Swiss:P35852 EC:6.3.5.3 and selenide, water dikinase Swiss:P16456 EC:2.7.9.3. The function of the C-terminal domain of ...	This family includes Hydrogen expression/formation protein HypE Swiss:P24193, AIR synthases Swiss:P08178 EC:6.3.3.1, FGAM synthase Swiss:P35852 EC:6.3.5.3 and selenide, water dikinase Swiss:P16456 EC:2.7.9.3. The function of the C-terminal domain of AIR synthase is unclear, but the cleft formed between N and C domains is postulated as a sulphate binding site [1].	Domain
A, B, C, D	PF00586	AIR synthase related protein, N-terminal domain (AIRS)	AIR synthase related protein, N-terminal domain	This family includes Hydrogen expression/formation protein HypE Swiss:P24193, AIR synthases Swiss:P08178 EC:6.3.3.1, FGAM synthase Swiss:P35852 EC:6.3.5.3 and selenide, water dikinase Swiss:P16456 EC:2.7.9.3. The N-terminal domain of AIR synthase fo ...	This family includes Hydrogen expression/formation protein HypE Swiss:P24193, AIR synthases Swiss:P08178 EC:6.3.3.1, FGAM synthase Swiss:P35852 EC:6.3.5.3 and selenide, water dikinase Swiss:P16456 EC:2.7.9.3. The N-terminal domain of AIR synthase forms the dimer interface of the protein, and is suggested as a putative ATP binding domain [1].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	HypE protein	-	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process gene expression macromolecule biosynthetic process protein maturation	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR036676	PurM-like, C-terminal domain superfamily	Homologous Superfamily
A, B, C, D	IPR010918	PurM-like, C-terminal domain	Domain
A, B, C, D	IPR016188	PurM-like, N-terminal domain	Domain
A, B, C, D	IPR036921	PurM-like, N-terminal domain superfamily	Homologous Superfamily
A, B, C, D	IPR011854	Carbamoyl dehydratase HypE	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.