Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Bd2qp8b_ All beta proteins Acid proteases Acid proteases Pepsin-like beta-secretase (memapsin) human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Ad2qp8a_ All beta proteins Acid proteases Acid proteases Pepsin-like beta-secretase (memapsin) human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
BSCOP2B SuperfamilyAcid proteases 8036280 3001059 SCOP2B (2022-06-29)
ASCOP2 FamilyPepsin-like 8023900 4002301 SCOP2 (2022-06-29)
ASCOP2 SuperfamilyAcid proteases 8036280 3001059 SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
BAsp_C_1e2qp8B2 A: beta barrelsX: cradle loop barrelH: RIFT-relatedT: acid proteaseF: Asp_C_1ECOD (1.6)
BAsp_Ne2qp8B3 A: beta barrelsX: cradle loop barrelH: RIFT-relatedT: acid proteaseF: Asp_NECOD (1.6)
AAsp_C_1e2qp8A2 A: beta barrelsX: cradle loop barrelH: RIFT-relatedT: acid proteaseF: Asp_C_1ECOD (1.6)
AAsp_Ne2qp8A3 A: beta barrelsX: cradle loop barrelH: RIFT-relatedT: acid proteaseF: Asp_NECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
B2.40.70.10 Mainly Beta Beta Barrel Cathepsin D, subunit A domain 1CATH (4.3.0)
A2.40.70.10 Mainly Beta Beta Barrel Cathepsin D, subunit A domain 1CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B
PF00026Eukaryotic aspartyl protease (Asp)Eukaryotic aspartyl protease- Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B
Beta-secretase 1