2OST | pdb_00002ost

The structure of a bacterial homing endonuclease : I-Ssp6803I

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
C [auth A]	SCOP2 Family	slr0915-like	8046833	4005320	SCOP2 (2022-06-29)
C [auth A]	SCOP2 Superfamily	Restriction endonuclease-like	8103670	3000104	SCOP2 (2022-06-29)
D [auth B]	SCOP2B Superfamily	Restriction endonuclease-like	8103670	3000104	SCOP2B (2022-06-29)
E [auth C]	SCOP2B Superfamily	Restriction endonuclease-like	8103670	3000104	SCOP2B (2022-06-29)
F [auth D]	SCOP2B Superfamily	Restriction endonuclease-like	8103670	3000104	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
C [auth A]	PDDEXK_5	e2ostA1	A: a/b three-layered sandwiches	X: Restriction endonuclease-like	H: Restriction endonuclease-like (From Topology)	T: Restriction endonuclease-like	F: PDDEXK_5	ECOD (1.6)
D [auth B]	PDDEXK_5	e2ostB1	A: a/b three-layered sandwiches	X: Restriction endonuclease-like	H: Restriction endonuclease-like (From Topology)	T: Restriction endonuclease-like	F: PDDEXK_5	ECOD (1.6)
E [auth C]	PDDEXK_5	e2ostC1	A: a/b three-layered sandwiches	X: Restriction endonuclease-like	H: Restriction endonuclease-like (From Topology)	T: Restriction endonuclease-like	F: PDDEXK_5	ECOD (1.6)
F [auth D]	PDDEXK_5	e2ostD1	A: a/b three-layered sandwiches	X: Restriction endonuclease-like	H: Restriction endonuclease-like (From Topology)	T: Restriction endonuclease-like	F: PDDEXK_5	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
C [auth A]	3.40.1350.10	Alpha Beta	3-Layer(aba) Sandwich	Trna Endonuclease	Chain: A, domain 1	CATH (4.3.0)
D [auth B]	3.40.1350.10	Alpha Beta	3-Layer(aba) Sandwich	Trna Endonuclease	Chain: A, domain 1	CATH (4.3.0)
E [auth C]	3.40.1350.10	Alpha Beta	3-Layer(aba) Sandwich	Trna Endonuclease	Chain: A, domain 1	CATH (4.3.0)
F [auth D]	3.40.1350.10	Alpha Beta	3-Layer(aba) Sandwich	Trna Endonuclease	Chain: A, domain 1	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
C [auth A], D [auth B], E [auth C], F [auth D]	PF11645	PD-(D/E)XK endonuclease (PDDEXK_5)	PD-(D/E)XK endonuclease	This family of endonucleases includes a group I intron-encoded endonuclease [1]. This family belongs to the PD-(D/E)XK superfamily [2-3].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth Y]	Synthetic DNA 29 MER	-	-	-
B [auth Z]	Synthetic DNA 29 MER	-	-	-
C [auth A], D [auth B], E [auth C], F [auth D]	Putative endonuclease	binding nucleic acid binding endonuclease activity nuclease activity hydrolase activity, acting on ester bonds hydrolase activity catalytic activity cation binding ion binding metal ion binding small molecule binding	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
C [auth A], D [auth B], E [auth C], F [auth D]	IPR021671	PD(D/E)XK endonuclease	Domain
C [auth A], D [auth B], E [auth C], F [auth D]	IPR011856	tRNA endonuclease-like domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.