1VLQ | pdb_00001vlq

Crystal structure of Acetyl xylan esterase (TM0077) from Thermotoga maritima at 2.10 A resolution

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1vlqa_	Alpha and beta proteins (a/b)	alpha/beta-Hydrolases	alpha/beta-Hydrolases	Acetyl xylan esterase-like	Acetyl xylan esterase TM0077	(Thermotoga maritima MSB8 ) [TaxId: 243274 ],	SCOPe (2.08)
C	d1vlqc_	Alpha and beta proteins (a/b)	alpha/beta-Hydrolases	alpha/beta-Hydrolases	Acetyl xylan esterase-like	Acetyl xylan esterase TM0077	(Thermotoga maritima MSB8 ) [TaxId: 243274 ],	SCOPe (2.08)
D	d1vlqd_	Alpha and beta proteins (a/b)	alpha/beta-Hydrolases	alpha/beta-Hydrolases	Acetyl xylan esterase-like	Acetyl xylan esterase TM0077	(Thermotoga maritima MSB8 ) [TaxId: 243274 ],	SCOPe (2.08)
G	d1vlqg_	Alpha and beta proteins (a/b)	alpha/beta-Hydrolases	alpha/beta-Hydrolases	Acetyl xylan esterase-like	Acetyl xylan esterase TM0077	(Thermotoga maritima MSB8 ) [TaxId: 243274 ],	SCOPe (2.08)
J	d1vlqj_	Alpha and beta proteins (a/b)	alpha/beta-Hydrolases	alpha/beta-Hydrolases	Acetyl xylan esterase-like	Acetyl xylan esterase TM0077	(Thermotoga maritima MSB8 ) [TaxId: 243274 ],	SCOPe (2.08)
L	d1vlql_	Alpha and beta proteins (a/b)	alpha/beta-Hydrolases	alpha/beta-Hydrolases	Acetyl xylan esterase-like	Acetyl xylan esterase TM0077	(Thermotoga maritima MSB8 ) [TaxId: 243274 ],	SCOPe (2.08)
B	d1vlqb_	Alpha and beta proteins (a/b)	alpha/beta-Hydrolases	alpha/beta-Hydrolases	Acetyl xylan esterase-like	Acetyl xylan esterase TM0077	(Thermotoga maritima MSB8 ) [TaxId: 243274 ],	SCOPe (2.08)
E	d1vlqe_	Alpha and beta proteins (a/b)	alpha/beta-Hydrolases	alpha/beta-Hydrolases	Acetyl xylan esterase-like	Acetyl xylan esterase TM0077	(Thermotoga maritima MSB8 ) [TaxId: 243274 ],	SCOPe (2.08)
F	d1vlqf_	Alpha and beta proteins (a/b)	alpha/beta-Hydrolases	alpha/beta-Hydrolases	Acetyl xylan esterase-like	Acetyl xylan esterase TM0077	(Thermotoga maritima MSB8 ) [TaxId: 243274 ],	SCOPe (2.08)
H	d1vlqh_	Alpha and beta proteins (a/b)	alpha/beta-Hydrolases	alpha/beta-Hydrolases	Acetyl xylan esterase-like	Acetyl xylan esterase TM0077	(Thermotoga maritima MSB8 ) [TaxId: 243274 ],	SCOPe (2.08)
I	d1vlqi_	Alpha and beta proteins (a/b)	alpha/beta-Hydrolases	alpha/beta-Hydrolases	Acetyl xylan esterase-like	Acetyl xylan esterase TM0077	(Thermotoga maritima MSB8 ) [TaxId: 243274 ],	SCOPe (2.08)
K	d1vlqk_	Alpha and beta proteins (a/b)	alpha/beta-Hydrolases	alpha/beta-Hydrolases	Acetyl xylan esterase-like	Acetyl xylan esterase TM0077	(Thermotoga maritima MSB8 ) [TaxId: 243274 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Acetyl xylan esterase-like	8029119	4003110	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	alpha/beta-Hydrolases	8041498	3000102	SCOP2 (2022-06-29)
C	SCOP2B Superfamily	alpha/beta-Hydrolases	8041498	3000102	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	alpha/beta-Hydrolases	8041498	3000102	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	alpha/beta-Hydrolases	8041498	3000102	SCOP2B (2022-06-29)
J	SCOP2B Superfamily	alpha/beta-Hydrolases	8041498	3000102	SCOP2B (2022-06-29)
L	SCOP2B Superfamily	alpha/beta-Hydrolases	8041498	3000102	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	alpha/beta-Hydrolases	8041498	3000102	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	alpha/beta-Hydrolases	8041498	3000102	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	alpha/beta-Hydrolases	8041498	3000102	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	alpha/beta-Hydrolases	8041498	3000102	SCOP2B (2022-06-29)
I	SCOP2B Superfamily	alpha/beta-Hydrolases	8041498	3000102	SCOP2B (2022-06-29)
K	SCOP2B Superfamily	alpha/beta-Hydrolases	8041498	3000102	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	AXE1	e1vlqA1	A: a/b three-layered sandwiches	X: alpha/beta-Hydrolases (From Topology)	H: alpha/beta-Hydrolases (From Topology)	T: alpha/beta-Hydrolases	F: AXE1	ECOD (1.6)
C	AXE1	e1vlqC1	A: a/b three-layered sandwiches	X: alpha/beta-Hydrolases (From Topology)	H: alpha/beta-Hydrolases (From Topology)	T: alpha/beta-Hydrolases	F: AXE1	ECOD (1.6)
D	AXE1	e1vlqD1	A: a/b three-layered sandwiches	X: alpha/beta-Hydrolases (From Topology)	H: alpha/beta-Hydrolases (From Topology)	T: alpha/beta-Hydrolases	F: AXE1	ECOD (1.6)
G	AXE1	e1vlqG1	A: a/b three-layered sandwiches	X: alpha/beta-Hydrolases (From Topology)	H: alpha/beta-Hydrolases (From Topology)	T: alpha/beta-Hydrolases	F: AXE1	ECOD (1.6)
J	AXE1	e1vlqJ1	A: a/b three-layered sandwiches	X: alpha/beta-Hydrolases (From Topology)	H: alpha/beta-Hydrolases (From Topology)	T: alpha/beta-Hydrolases	F: AXE1	ECOD (1.6)
L	AXE1	e1vlqL1	A: a/b three-layered sandwiches	X: alpha/beta-Hydrolases (From Topology)	H: alpha/beta-Hydrolases (From Topology)	T: alpha/beta-Hydrolases	F: AXE1	ECOD (1.6)
B	AXE1	e1vlqB1	A: a/b three-layered sandwiches	X: alpha/beta-Hydrolases (From Topology)	H: alpha/beta-Hydrolases (From Topology)	T: alpha/beta-Hydrolases	F: AXE1	ECOD (1.6)
E	AXE1	e1vlqE1	A: a/b three-layered sandwiches	X: alpha/beta-Hydrolases (From Topology)	H: alpha/beta-Hydrolases (From Topology)	T: alpha/beta-Hydrolases	F: AXE1	ECOD (1.6)
F	AXE1	e1vlqF1	A: a/b three-layered sandwiches	X: alpha/beta-Hydrolases (From Topology)	H: alpha/beta-Hydrolases (From Topology)	T: alpha/beta-Hydrolases	F: AXE1	ECOD (1.6)
H	AXE1	e1vlqH1	A: a/b three-layered sandwiches	X: alpha/beta-Hydrolases (From Topology)	H: alpha/beta-Hydrolases (From Topology)	T: alpha/beta-Hydrolases	F: AXE1	ECOD (1.6)
I	AXE1	e1vlqI1	A: a/b three-layered sandwiches	X: alpha/beta-Hydrolases (From Topology)	H: alpha/beta-Hydrolases (From Topology)	T: alpha/beta-Hydrolases	F: AXE1	ECOD (1.6)
K	AXE1	e1vlqK1	A: a/b three-layered sandwiches	X: alpha/beta-Hydrolases (From Topology)	H: alpha/beta-Hydrolases (From Topology)	T: alpha/beta-Hydrolases	F: AXE1	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.50.1820	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Alpha/Beta hydrolase fold, catalytic domain	CATH (4.3.0)
C	3.40.50.1820	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Alpha/Beta hydrolase fold, catalytic domain	CATH (4.3.0)
D	3.40.50.1820	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Alpha/Beta hydrolase fold, catalytic domain	CATH (4.3.0)
G	3.40.50.1820	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Alpha/Beta hydrolase fold, catalytic domain	CATH (4.3.0)
J	3.40.50.1820	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Alpha/Beta hydrolase fold, catalytic domain	CATH (4.3.0)
L	3.40.50.1820	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Alpha/Beta hydrolase fold, catalytic domain	CATH (4.3.0)
B	3.40.50.1820	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Alpha/Beta hydrolase fold, catalytic domain	CATH (4.3.0)
E	3.40.50.1820	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Alpha/Beta hydrolase fold, catalytic domain	CATH (4.3.0)
F	3.40.50.1820	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Alpha/Beta hydrolase fold, catalytic domain	CATH (4.3.0)
H	3.40.50.1820	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Alpha/Beta hydrolase fold, catalytic domain	CATH (4.3.0)
I	3.40.50.1820	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Alpha/Beta hydrolase fold, catalytic domain	CATH (4.3.0)
K	3.40.50.1820	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Alpha/Beta hydrolase fold, catalytic domain	CATH (4.3.0)

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	acetyl xylan esterase	cation binding ion binding binding calcium ion binding metal ion binding small molecule binding hydrolase activity, acting on ester bonds carboxylic ester hydrolase activity acetylxylan esterase activity hydrolase activity catalytic activity cephalosporin-C deacetylase activity deacetylase activity deacylase activity	beta-lactam antibiotic metabolic process oxoacid metabolic process carboxylic acid metabolic process organic acid metabolic process lactam metabolic process amine metabolic process antibiotic metabolic process cephalosporin C metabolic process small molecule metabolic process metabolic process cellular process sulfur compound metabolic process cephalosporin metabolic process amide metabolic process beta-lactam antibiotic metabolic process oxoacid metabolic process carboxylic acid metabolic process organic acid metabolic process lactam metabolic process amine metabolic process antibiotic metabolic process cephalosporin C metabolic process small molecule metabolic process metabolic process cellular process sulfur compound metabolic process cephalosporin metabolic process amide metabolic process carbohydrate metabolic process polysaccharide metabolic process primary metabolic process macromolecule metabolic process hemicellulose metabolic process cell wall organization or biogenesis xylan metabolic process cell wall polysaccharide metabolic process cell wall macromolecule metabolic process catabolic process glucan catabolic process beta-glucan metabolic process carbohydrate catabolic process macromolecule catabolic process glucan metabolic process beta-glucan catabolic process polysaccharide catabolic process cellulose catabolic process cellulose metabolic process	cellular anatomical structure intracellular anatomical structure cytoplasm

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR029058	Alpha/Beta hydrolase fold	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR008391	Acetyl xylan esterase domain	Domain
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	IPR039069	Carbohydrate esterase 7 family	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.