Annotations: 1C0E

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1c0ea_	Alpha and beta proteins (a/b)	Phosphotyrosine protein phosphatases I-like	Phosphotyrosine protein phosphatases I	Low-molecular-weight phosphotyrosine protein phosphatases	Tyrosine phosphatase	cattle (Bos taurus ) [TaxId: 9913 ],	SCOPe (2.08)
B	d1c0eb_	Alpha and beta proteins (a/b)	Phosphotyrosine protein phosphatases I-like	Phosphotyrosine protein phosphatases I	Low-molecular-weight phosphotyrosine protein phosphatases	Tyrosine phosphatase	cattle (Bos taurus ) [TaxId: 9913 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Phosphotyrosine protein phosphatases I	8044340	3000290	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Phosphotyrosine protein phosphatases I	8044340	3000290	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	LMWPc	e1c0eA1	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: Flavoproteins/Phosphotyrosine protein phosphatases-like	T: Phosphotyrosine protein phosphatases I-like	F: LMWPc	ECOD (1.6)
B	LMWPc	e1c0eB1	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: Flavoproteins/Phosphotyrosine protein phosphatases-like	T: Phosphotyrosine protein phosphatases I-like	F: LMWPc	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.50.2300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Response regulator	CATH (4.3.0)
B	3.40.50.2300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Response regulator	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF01451	Low molecular weight phosphotyrosine protein phosphatase (LMWPc)	Low molecular weight phosphotyrosine protein phosphatase		Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	PROTEIN (TYROSINE PHOSPHATASE (ORTHOPHOSPHORIC MONOESTER PHOSPHOHYDROLASE))	phosphoric ester hydrolase activity phosphoprotein phosphatase activity non-membrane spanning protein tyrosine phosphatase activity catalytic activity, acting on a protein hydrolase activity, acting on ester bonds protein tyrosine phosphatase activity phosphatase activity hydrolase activity catalytic activity histone modifying activity histone phosphatase activity histone H2AXY142 phosphatase activity protein tyrosine phosphatase activity, metal-dependent acid phosphatase activity	-	cellular anatomical structure intracellular anatomical structure cytoplasm

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR002115	Protein-tyrosine phosphatase, low molecular weight, mammalian	Family
A, B	IPR050438	Low Molecular Weight Phosphotyrosine Protein Phosphatase	Family
A, B	IPR017867	Protein-tyrosine phosphatase, low molecular weight	Family
A, B	IPR036196	Phosphotyrosine protein phosphatase I superfamily	Homologous Superfamily
A, B	IPR023485	Phosphotyrosine protein phosphatase I	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.