Crystal structure of meta-AAC0038, an environmental aminoglycoside resistance enzyme, mutant H168A in abortive complex with sisomicin-CoA

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RCSB PDB Mol* Viewer 2.11.2 [1/27/2025, 4:56:27 PM]
Sequence of
     ​V​​S​​S​​R​​V​​S​​T​​R​​S​​S​11   ​L​​A​​E​​D​​L​​R​​A​​I​​G​​L​21   ​A​​D​​G​​D​​A​​V​​L​​V​​H​​A​31   ​A​​L​​R​​K​​V​​G​​K​​I​​V​​G​41   ​G​​P​​D​​D​​I​​L​​D​​A​​M​​R​51   ​D​​V​​I​​G​​P​​A​​G​​T​​V​​L​61   ​G​​Y​​A​​D​​W​​Q​​L​​E​​D​​E​71   ​I​​R​​D​​D​​P​​A​​M​​R​​E​​H​81   ​I​​P​​A​​F​​D​​P​​L​​R​​S​​R​91   ​S​​I​​R​​D​​N​​G​​F​​W​​P​​E​101  ​L​​I​​R​​T​​T​​P​​G​​A​​L​​R​111  ​S​​A​​S​​P​​G​​A​​S​​M​​A​​A​121  ​I​​G​​G​​E​​A​​E​​W​​F​​T​​A​131  ​D​​H​​A​​L​​D​​Y​​G​​Y​​G​​P​141  ​R​​S​​P​​L​​G​​K​​L​​V​​E​​A​151  ​K​​G​​K​​V​​L​​M​​L​​G​​A​​P​161  ​L​​D​​T​​M​​T​​L​​L​​A​​H​​A​171  ​E​​H​​L​​A​​D​​F​​P​​N​​K​​R​181  ​I​​L​​R​​Y​​E​​A​​P​​I​​L​​V​191  ​D​​G​​E​​K​​V​​W​​R​​W​​F​​E​201  ​E​​F​​D​​T​​S​​D​​P​​P​​D​​G​211  ​L​​A​​D​​D​​Y​​F​​A​​G​​I​​V​221  ​E​​E​​F​​L​​A​​T​​G​​R​​G​​K​231  ​R​​G​​K​​I​​G​​E​​A​​S​​S​​V​241  ​L​​V​​P​​A​​D​​E​​I​​V​​A​​F​251  ​A​​V​​D​​W​​L​​E​​R​​W​​G​​R​261  ​T​​A​​R​
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