- FASTA Sequence
- PDBx/mmCIF Format
- PDBx/mmCIF Format (gz)
- BinaryCIF Format (gz)
- PDB Format
- PDB Format (gz)
- PDBML/XML Format (gz)
- Structure Factors (CIF)
- Structure Factors (CIF - gz)
- Validation Full PDF
- Validation (XML - gz)
- Validation (CIF - gz)
- Validation 2fo-fc coefficients (CIF - gz)
- Validation fo-fc coefficients (CIF - gz)
- Biological Assembly 1 (CIF - gz)
- Biological Assembly 1 (PDB - gz)
4AN2
Crystal structures of human MEK1 with carboxamide-based allosteric inhibitor XL518 (GDC-0973), or related analogs.
WebGL does not seem to be available.
This can be caused by an outdated browser, graphics card driver issue, or bad weather. Sometimes, just restarting the browser helps. Also, make sure hardware acceleration is enabled in your browser.
For a list of supported browsers, refer to http://caniuse.com/#feat=webgl.
Welcome
RCSB PDB Mol* Viewer 2.11.1 [12/17/2024, 1:59:56 PM]
Sequence of
58 MALGELKDDD68 FEKISELGAG78 NGGVVFKVSH88 KPSGLVMARK98 LIHLEIKPAI108 RNQIIRELQV118 LHECNSPYIV128 GFYGAFYSDG138 EISICMEHMD148 GGSLDQVLKK158 AGRIPEQILG168 KVSIAVIKGL178 TYLREKHKIM188 HRDVKPSNIL198 VNSRGEIKLC208 DFGVSGQLID218 EMANEFVGTR228 SYMSPERLQG238 THYSVQSDIW248 SMGLSLVEMA258 VGRYPRPPMA310 IFELLDYIVN320 EPPPKLPSAV330 FSLEFQDFVN340 KCLIKNPAER350 ADLKQLMVHA360 FIKRSDAEEV370 DFAGWLCSTI380 GLNQPSTPTH AAGEGHHHHH H
Type
Asm Id
Dynamic Bonds
Load File(s)
Select a different viewer