Crystal Structure of the N-terminal domain of an HSP90 from Plasmodium Falciparum, PFL1070c in the presence of a thienopyrimidine derivative

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RCSB PDB Mol* Viewer 2.11.2 [1/27/2025, 4:56:27 PM]
Sequence of
     ​M​​H​​H​​H​​H​​H​​H​​S​​S​​G​     ​R​​E​​N​​L​​Y​​F​​Q​​G​​P​​T​70   ​E​​S​​M​​E​​S​​H​​Q​​Y​​Q​​T​80   ​E​​V​​T​​R​​L​​M​​D​​I​​I​​V​90   ​N​​S​​L​​Y​​T​​Q​​K​​E​​V​​F​100  ​L​​R​​E​​L​​I​​S​​N​​A​​A​​D​110  ​A​​L​​E​​K​​I​​R​​F​​L​​S​​L​120  ​S​​D​​E​​S​​V​​L​​G​​E​​E​​K​130  ​K​​L​​E​​I​​R​​I​​S​​A​​N​​K​140  ​E​​K​​N​​I​​L​​S​​I​​T​​D​​T​150  ​G​​I​​G​​M​​T​​K​​V​​D​​L​​I​160  ​N​​N​​L​​G​​T​​I​​A​​K​​S​​G​170  ​T​​S​​N​​F​​L​​E​​A​​I​​S​​K​180  ​S​​G​​G​​D​​M​​S​​L​​I​​G​​Q​190  ​F​​G​​V​​G​​F​​Y​​S​​A​​F​​L​200  ​V​​A​​D​​K​​V​​I​​V​​Y​​T​​K​210  ​N​​N​​D​​D​​E​​Q​​Y​​I​​W​​E​220  ​S​​T​​A​​D​​A​​K​​F​​T​​I​​Y​230  ​K​​D​​P​​R​​G​​A​​T​​L​​K​​R​240  ​G​​T​​R​​I​​S​​L​​H​​L​​K​​E​250  ​D​​A​​T​​N​​L​​L​​N​​D​​K​​K​260  ​L​​M​​D​​L​​I​​S​​K​​Y​​S​​Q​270  ​F​​I​​Q​​F​​P​​I​​Y​​L​​L​​H​280  ​E​​N​​V​​Y​​T​​E​​E​​V​​L​​A​290  ​D​​I​​A​​K​​D​​M​​V​​N​​D​​P​300  ​N​​Y​​D​​S​​V​​K​​V​​E​​E​​T​310  ​D​​D​​P​​N​​K​​K​​T​​R​​T​​V​320  ​E​​K​​K​​V​​K​​K​​W​​T​​L​​M​330  ​N​
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