Download MendeleyCrystal Structure of TTHA0275 from Thermus thermophilus (HB8)
Demirci, H., Belardinelli, R., Jogl, G.To be published.
4X3L | pdb_00004x3l
Crystal Structure of TTHA0275 from Thermus thermophilus (HB8) in complex with 5'-methylthioadenosine in space group P21212
- PDB DOI: https://doi.org/10.2210/pdb4X3L/pdb
- Classification: TRANSFERASE
- Organism(s): Thermus thermophilus HB8
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2014-12-01 Released: 2016-01-20
- Funding Organization(s): National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.70 Å
- R-Value Free: 0.207 (Depositor), 0.210 (DCC)
- R-Value Work: 0.185 (Depositor), 0.190 (DCC)
- R-Value Observed: 0.186 (Depositor)
Starting Model: experimental
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This is version 1.4 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| RNA 2'-O ribose methyltransferase | 260 | Thermus thermophilus HB8 | Mutation(s): 0 Gene Names: TTHA0275 |  | |
UniProt | |||||
Find proteins for Q5SLL8 (Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)) Explore Q5SLL8 Go to UniProtKB: Q5SLL8 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q5SLL8 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| MTA Query on MTA | C [auth A], F [auth B] | 5'-DEOXY-5'-METHYLTHIOADENOSINE C11 H15 N5 O3 S WUUGFSXJNOTRMR-IOSLPCCCSA-N |  | ||
| CL Query on CL | D [auth A], E [auth A], G [auth B], H [auth B], I [auth B] | CHLORIDE ION Cl VEXZGXHMUGYJMC-UHFFFAOYSA-M |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.70 Å
- R-Value Free: 0.207 (Depositor), 0.210 (DCC)
- R-Value Work: 0.185 (Depositor), 0.190 (DCC)
- R-Value Observed: 0.186 (Depositor)
Space Group: P 21 21 2
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 111.17 | α = 90 |
| b = 115.95 | β = 90 |
| c = 58.68 | γ = 90 |
| Software Name | Purpose |
|---|---|
| PHENIX | refinement |
| PDB_EXTRACT | data extraction |
| XDS | data scaling |
| PHASER | phasing |
Entry History & Funding Information
Deposition Data
- Released Date: 2016-01-20 Deposition Author(s): Demirci, H., Belardinelli, R., Jogl, G.
| Funding Organization | Location | Grant Number |
|---|---|---|
| National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS) | United States | GM019756 |
| National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS) | United States | GM094157 |
Revision History (Full details and data files)
- Version 1.0: 2016-01-20
Type: Initial release - Version 1.1: 2017-03-22
Changes: Source and taxonomy - Version 1.2: 2017-09-13
Changes: Author supporting evidence - Version 1.3: 2019-12-25
Changes: Author supporting evidence - Version 1.4: 2023-09-27
Changes: Data collection, Database references, Refinement description
