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235,183 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Structure Keywords HAS EXACT PHRASE "transcription activator"

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Search Summary

This query matches 73 Structures.

Refinements

Structure Determination Methodology

experimental (73)

Scientific Name of Source Organism

	Homo sapiens (33)
	Escherichia coli (11)
	Danio rerio (6)
	Saccharomyces cerevisiae (6)
	Bacillus subtilis (4)
	Bacillus thuringiensis Bt407 (2)
	Corynebacterium glutamicum (2)
	Mus musculus (2)
	Streptomyces lividans (2)
	synthetic construct (2)

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Taxonomy

	Eukaryota (43)
	Bacteria (29)
	Eukaryota (eukaryotes) (2)
	other sequences (2)
	Duplodnaviria (1)

Experimental Method

	X-RAY DIFFRACTION (68)
	SOLUTION NMR (5)

Polymer Entity Type

	Protein (73)
	DNA (17)

Refinement Resolution (Å)

	1.0 - 1.5 (1)
	1.5 - 2.0 (10)
	2.0 - 2.5 (23)
	2.5 - 3.0 (24)
	3.0 - 3.5 (8)
	3.5 - 4.0 (1)
	4.0 - 4.5 (1)

Release Date

	1995 - 1999 (3)
	2000 - 2004 (16)
	2005 - 2009 (17)
	2010 - 2014 (30)
	2015 - 2019 (7)

Enzyme Classification Name

	Transferases (7)
	Oxidoreductases (3)
	Hydrolases (1)

Symmetry Type

	Cyclic (45)
	Asymmetric (29)

SCOP Classification

	All alpha proteins (25)
	Artifacts (10)
	All beta proteins (11)
	Alpha and beta proteins (a+b) (5)
	Alpha and beta proteins (a/b) (1)
	Peptides (3)
	Small proteins (2)
	Multi-domain proteins (alpha and beta) (1)

AllSelected

1 to 25 of 73 Structures

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1BOW \| pdb_00001bow	Download File View File

MULTIDRUG-BINDING DOMAIN OF TRANSCRIPTION ACTIVATOR BMRR (APO FORM)

Zheleznova, E.E., Markham, P.N., Neyfakh, A.A., Brennan, R.G.

(1999) Cell 96: 353-362

Released	1999-08-06
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Bacillus subtilis
Macromolecule	MULTIDRUG-EFFLUX TRANSPORTER 1 REGULATOR BMRR (protein)
Unique Ligands	MN

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1ETK \| pdb_00001etk	Download File View File

THE CRYSTAL STRUCTURE OF E. COLI FIS MUTANT Q68A

Cheng, Y.S., Yang, W.Z., Johnson, R.C., Yuan, H.S.

(2000) J Mol Biology 302: 1139-1151

Released	2000-10-11
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Escherichia coli
Macromolecule	FACTOR FOR INVERSION STIMULATION (protein)

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1ETO \| pdb_00001eto	Download File View File

THE CRYSTAL STRUCTURE OF E. COLI FIS MUTANT R71L

Cheng, Y.S., Yang, W.Z., Johnson, R.C., Yuan, H.S.

(2000) J Mol Biology 302: 1139-1151

Released	2000-10-11
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Escherichia coli
Macromolecule	FACTOR FOR INVERSION STIMULATION (protein)

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1ETQ \| pdb_00001etq	Download File View File

THE CRYSTAL STRUCTURE OF E. COLI FIS MUTANT R71Y

Cheng, Y.S., Yang, W.Z., Johnson, R.C., Yuan, H.S.

(2000) J Mol Biology 302: 1139-1151

Released	2000-10-11
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Escherichia coli
Macromolecule	FACTOR FOR INVERSION STIMULATION (protein)

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1ETV \| pdb_00001etv	Download File View File

THE CRYSTAL STRUCTURE OF E. COLI FIS MUTANT G72A

Cheng, Y.S., Yang, W.Z., Johnson, R.C., Yuan, H.S.

(2000) J Mol Biology 302: 1139-1151

Released	2000-10-11
Method	X-RAY DIFFRACTION 2 Å
Organisms	Escherichia coli
Macromolecule	FACTOR FOR INVERSION STIMULATION (protein)

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1ETW \| pdb_00001etw	Download File View File

THE CRYSTAL STRUCTURE OF E. COLI FIS MUTANT G72D

Cheng, Y.S., Yang, W.Z., Johnson, R.C., Yuan, H.S.

(2000) J Mol Biology 302: 1139-1151

Released	2000-10-11
Method	X-RAY DIFFRACTION 2 Å
Organisms	Escherichia coli
Macromolecule	FACTOR FOR INVERSION STIMULATION (protein)

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1ETX \| pdb_00001etx	Download File View File

THE CRYSTAL STRUCTURE OF E. COLI FIS MUTANT Q74A

Cheng, Y.S., Yang, W.Z., Johnson, R.C., Yuan, H.S.

(2000) J Mol Biology 302: 1139-1151

Released	2000-10-11
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Escherichia coli
Macromolecule	FACTOR FOR INVERSION STIMULATION (protein)

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1ETY \| pdb_00001ety	Download File View File

THE CRYSTAL STRUCTURE OF E. COLI WILD-TYPE FIS

Cheng, Y.S., Yang, W.Z., Johnson, R.C., Yuan, H.S.

(2000) J Mol Biology 302: 1139-1151

Released	2000-10-11
Method	X-RAY DIFFRACTION 2 Å
Organisms	Escherichia coli
Macromolecule	FACTOR FOR INVERSION STIMULATION (protein)

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1HZ4 \| pdb_00001hz4	Download File View File

CRYSTAL STRUCTURE OF TRANSCRIPTION FACTOR MALT DOMAIN III

Steegborn, C., Danot, O., Clausen, T., Huber, R.

(2001) Structure 9: 1051-1060

Released	2001-11-28
Method	X-RAY DIFFRACTION 1.45 Å
Organisms	Escherichia coli
Macromolecule	MALT REGULATORY PROTEIN (protein)
Unique Ligands	BEZ, GOL, SO4

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1M6U \| pdb_00001m6u	Download File View File

Crystal Structure of a Novel DNA-binding domain from Ndt80, a Transcriptional Activator Required for Meiosis in Yeast

Montano, S.P., Cote, M.L., Fingerman, I., Pierce, M., Vershon, A.K., Georgiadis, M.M.

(2002) Proc Natl Acad Sci U S A 99: 14041-14046

Released	2002-11-06
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	Ndt80 protein (protein)
Unique Ligands	SO4

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1M7U \| pdb_00001m7u	Download File View File

Crystal structure of a novel DNA-binding domain from Ndt80, a transcriptional activator required for meiosis in yeast

Montano, S.P., Cote, M.L., Fingerman, I., Pierce, M., Vershon, A.K., Georgiadis, M.M.

(2002) Proc Natl Acad Sci U S A 99: 14041-14046

Released	2002-11-06
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	Ndt80 protein (protein)

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1SSE \| pdb_00001sse	Download File View File

Solution structure of the oxidized form of the Yap1 redox domain

Wood, M.J., Storz, G., Tjandra, N.

(2004) Nature 430: 917-921

Released	2004-08-31
Method	SOLUTION NMR
Organisms	Saccharomyces cerevisiae
Macromolecule	AP-1 like transcription factor YAP1 (protein)

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1UUR \| pdb_00001uur	Download File View File

Structure of an activated Dictyostelium STAT in its DNA-unbound form

Soler-Lopez, M., Petosa, C., Fukuzawa, M., Ravelli, R., Williams, J.G., Muller, C.W.

(2004) Mol Cell 13: 791

Released	2004-03-26
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Dictyostelium discoideum
Macromolecule	STATA PROTEIN (protein)

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1ZES \| pdb_00001zes	Download File View File

BeF3- activated PhoB receiver domain

Bachhawat, P., Montelione, G.T., Stock, A.M.

(2005) Structure 13: 1353-1363

Released	2005-09-20
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Escherichia coli
Macromolecule	Phosphate regulon transcriptional regulatory protein phoB (protein)
Unique Ligands	BEF, MG

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1ZPQ \| pdb_00001zpq	Download File View File

STRUCTURE OF BACTERIOPHAGE LAMBDA CII protein

Jain, D., Kim, Y., Maxwell, K.L., Beasley, S., Gussin, G.N., Edwards, A.M., Joachimiak, A., Darst, S.A., Midwest Center for Structural Genomics (MCSG)

(2005) Mol Cell 19: 259-269

Released	2005-08-23
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Lambdavirus lambda
Macromolecule	Regulatory protein CII (protein)

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2AVU \| pdb_00002avu	Download File View File

Structure of the Escherichia coli FlhDC complex, a prokaryotic heteromeric regulator of transcription

Wang, S., Fleming, R.T., Westbrook, E.M., Matsumura, P., McKay, D.B.

(2006) J Mol Biology 355: 798-808

Released	2005-12-13
Method	X-RAY DIFFRACTION 3 Å
Organisms	Escherichia coli
Macromolecule	Flagellar transcriptional activator flhC (protein) Transcriptional activator flhD (protein)
Unique Ligands	ZN

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2BOW \| pdb_00002bow	Download File View File

MULTIDRUG-BINDING DOMAIN OF TRANSCRIPTION ACTIVATOR BMRR IN COMPLEX WITH A LIGAND, TETRAPHENYLPHOSPHONIUM

Zheleznova, E.E., Markham, P.N., Neyfakh, A.A., Brennan, R.G.

(1999) Cell 96: 353-362

Released	1999-08-06
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Bacillus subtilis
Macromolecule	MULTIDRUG-EFFLUX TRANSPORTER 1 REGULATOR BMRR (protein)
Unique Ligands	MN, P4P, SO4

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2F4B \| pdb_00002f4b	Download File View File

Crystal structure of the ligand binding domain of human PPAR-gamma in complex with an agonist

Lu, I.L., Peng, Y.H., Mahindroo, N., Hsieh, H.P., Wu, S.Y.

(2006) J Med Chem 49: 1212-1216

Released	2006-02-14
Method	X-RAY DIFFRACTION 2.07 Å
Organisms	Homo sapiens
Macromolecule	Peroxisome proliferator-activated receptor gamma (protein)
Unique Ligands	EHA

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2G0G \| pdb_00002g0g	Download File View File

Structure-based drug design of a novel family of PPAR partial agonists: virtual screening, x-ray crystallography and in vitro/in vivo biological activities

Lu, I.L., Peng, Y.H., Huang, C.F., Lin, Y.T., Hsu, J.T.A., Wu, S.Y.

(2006) J Med Chem 49: 2703-2712

Released	2006-05-16
Method	X-RAY DIFFRACTION 2.54 Å
Organisms	Homo sapiens
Macromolecule	Peroxisome proliferator-activated receptor gamma (protein)
Unique Ligands	SP0

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2G0H \| pdb_00002g0h	Download File View File

Structure-based drug design of a novel family of PPAR partial agonists: virtual screening, x-ray crystallography and in vitro/in vivo biological activities

Lu, I.L., Peng, Y.H., Huang, C.F., Lin, Y.T., Hsu, J.T.A., Wu, S.Y.

(2006) J Med Chem 49: 2703-2712

Released	2006-05-16
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Homo sapiens
Macromolecule	Peroxisome proliferator-activated receptor gamma (protein)
Unique Ligands	SP3

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2HTJ \| pdb_00002htj	Download File View File

NMR structure of E.coli PapI

Kawamura, T., Zhou, H., Le, L.U.K., Dahlquist, F.W.

(2007) J Mol Biology 365: 1130-1142

Released	2007-01-30
Method	SOLUTION NMR
Organisms	Escherichia coli
Macromolecule	P fimbrial regulatory protein KS71A (protein)

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3F51 \| pdb_00003f51	Download File View File

Crystal Structure of the clp gene regulator ClgR from Corynebacterium glutamicum

Russo, S., Schweitzer, J.E., Polen, T., Bott, M., Pohl, E.

(2009) J Biological Chem 284: 5208-5216

Released	2008-11-18
Method	X-RAY DIFFRACTION 2.05 Å
Organisms	Corynebacterium glutamicum
Macromolecule	Clp gene regulator (ClgR) (protein)
Unique Ligands	ACT, MPD

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3F52 \| pdb_00003f52	Download File View File

Crystal structure of the clp gene regulator ClgR from C. glutamicum

Russo, S., Schweitzer, J.E., Polen, T., Bott, M., Pohl, E.

(2009) J Biological Chem 284: 5208-5216

Released	2008-11-18
Method	X-RAY DIFFRACTION 1.75 Å
Organisms	Corynebacterium glutamicum
Macromolecule	clp gene regulator (ClgR) (protein)
Unique Ligands	GOL

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3LUR \| pdb_00003lur	Download File View File

Crystal structure of Putative bacterial transcription regulation protein (NP_372959.1) from Staphylococcus aureus MU50 at 1.81 A resolution

Joint Center for Structural Genomics (JCSG)

To be published

Released	2010-03-09
Method	X-RAY DIFFRACTION 1.81 Å
Organisms	Staphylococcus aureus subsp. aureus Mu50
Macromolecule	Putative bacterial transcription regulation protein (protein)
Unique Ligands	EDO, PEG, PG4