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234,136 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Structure Keywords HAS EXACT PHRASE "SH3 DOMAIN"

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Search Summary

This query matches 19 Structures.

Refinements

Structure Determination Methodology

experimental (19)

Scientific Name of Source Organism

	Homo sapiens (12)
	Gallus gallus (5)
	Mus musculus (2)
	Human immunodeficiency virus 1 (1)
	Saimiriine gammaherpesvirus 2 (1)

Taxonomy

	Eukaryota (19)
	Duplodnaviria (1)
	Eukaryota (eukaryotes) (1)
	Riboviria (1)

Experimental Method

	X-RAY DIFFRACTION (13)
	SOLUTION NMR (6)

Polymer Entity Type

Protein (19)

Refinement Resolution (Å)

	1.0 - 1.5 (1)
	2.0 - 2.5 (6)
	2.5 - 3.0 (6)

Release Date

	1995 - 1999 (4)
	2000 - 2004 (6)
	2005 - 2009 (9)

Enzyme Classification Name

Transferases (5)

Membrane Protein Annotation

OPM (1)

Symmetry Type

	Asymmetric (16)
	Cyclic (3)

SCOP Classification

	All beta proteins (13)
	Alpha and beta proteins (a+b) (3)
	Artifacts (4)

AllSelected

1 to 19 of 19 Structures

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1B07 \| pdb_00001b07	Download File View File

CRK SH3 DOMAIN COMPLEXED WITH PEPTOID INHIBITOR

Nguyen, J.T., Turck, C.W., Cohen, F.E., Zuckermann, R.N., Lim, W.A.

(1998) Science 282: 2088-2092

Released	1999-01-06
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Mus musculus
Macromolecule	PROTEIN (PROTO-ONCOGENE CRK (CRK)) (protein) PROTEIN (SH3 PEPTOID INHIBITOR) (protein)
Unique Ligands	PYJ

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1BK2 \| pdb_00001bk2	Download File View File

A-SPECTRIN SH3 DOMAIN D48G MUTANT

Martinez, J.C., Pisabarro, M.T., Serrano, L.

(1998) Nat Struct Biol 5: 721-729

Released	1999-02-16
Method	X-RAY DIFFRACTION 2.01 Å
Organisms	Gallus gallus
Macromolecule	A-SPECTRIN (protein)

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1E0L \| pdb_00001e0l	Download File View File

FBP28WW domain from Mus musculus

Macias, M.J., Gervais, V., Civera, C., Oschkinat, H.

(2000) Nat Struct Biol 7: 375

Released	2000-04-20
Method	SOLUTION NMR
Organisms	Mus musculus
Macromolecule	FORMIN BINDING PROTEIN (protein)

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1E6G \| pdb_00001e6g	Download File View File

A-SPECTRIN SH3 DOMAIN A11V, V23L, M25I, V53I, V58L MUTANT

Vega, M.C., Serrano, L.

(2002) Nat Struct Biol 9: 485

Released	2002-05-23
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Gallus gallus
Macromolecule	SPECTRIN ALPHA CHAIN (protein)
Unique Ligands	SO4

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1E6H \| pdb_00001e6h	Download File View File

A-SPECTRIN SH3 DOMAIN A11V, M25I, V44I, V58L MUTANTS

Vega, M.C., Serrano, L.

(2002) Nat Struct Biol 9: 485

Released	2002-05-23
Method	X-RAY DIFFRACTION 2.01 Å
Organisms	Gallus gallus
Macromolecule	SPECTRIN ALPHA CHAIN (protein)

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1H8K \| pdb_00001h8k	Download File View File

A-SPECTRIN SH3 DOMAIN A11V, V23L, M25V, V53I, V58L MUTANT

Vega, M.C., Serrano, L.

(2002) Nat Struct Biol 9: 485

Released	2002-05-23
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Gallus gallus
Macromolecule	SPECTRIN ALPHA CHAIN (protein)

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1NEB \| pdb_00001neb	Download File View File

SH3 DOMAIN FROM HUMAN NEBULIN, NMR, MINIMIZED AVERAGE STRUCTURE

Politou, A.S., Pastore, A.

(1998) J Mol Biology 276: 189-202

Released	1997-12-24
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	NEBULIN (protein)

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1O7K \| pdb_00001o7k	Download File View File

human p47 PX domain complex with sulphates

Karathanassis, D., Bravo, J., Perisic, O., Pacold, C.M., Williams, R.L.

(2002) EMBO J 21: 5057

Released	2002-11-20
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	NEUTROPHIL CYTOSOL FACTOR 1 (protein)
Unique Ligands	SO4

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1UUE \| pdb_00001uue	Download File View File

a-SPECTRIN SH3 DOMAIN (V44T, D48G MUTANT)

Vega, M.C., Fernandez, A., Wilmanns, M., Serrano, L.

(2004) Proc Natl Acad Sci U S A 101: 2834

Released	2004-02-19
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Gallus gallus
Macromolecule	SPECTRIN ALPHA CHAIN (protein)

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1V1C \| pdb_00001v1c	Download File View File

Solution Structure of the SH3 domain of Obscurin

Pfuhl, M., Gautel, M.

To be published

Released	2005-04-14
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	OBSCURIN (protein)

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1W1F \| pdb_00001w1f	Download File View File

SH3 DOMAIN OF HUMAN LYN TYROSINE KINASE

Bauer, F., Schweimer, K., Hoffmann, S., Roesch, P., Sticht, H.

(2005) Protein Sci 14: 2487

Released	2005-07-06
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	TYROSINE-PROTEIN KINASE LYN (protein)

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1W6X \| pdb_00001w6x	Download File View File

SH3 domain of p40phox, component of the NADPH oxidase

Massenet, C., Chenavas, S., Cohen-Addad, C., Dagher, M.-C., Brandolin, G., Pebay-Peyroula, E., Fieschi, F.

(2005) J Biological Chem 280: 13752-13761

Released	2005-01-18
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	NEUTROPHIL CYTOSOL FACTOR 4 (protein)

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1W70 \| pdb_00001w70	Download File View File

SH3 domain of p40phox complexed with C-terminal polyProline region of p47phox

Massenet, C., Chenavas, S., Cohen-Addad, C., Dagher, M.-C., Brandolin, G., Pebay-Peyroula, E., Fieschi, F.

(2005) J Biological Chem 280: 13752

Released	2005-01-18
Method	X-RAY DIFFRACTION 1.46 Å
Organisms	Homo sapiens
Macromolecule	NEUTROPHIL CYTOSOL FACTOR 1 (protein) NEUTROPHIL CYTOSOL FACTOR 4 (protein)
Unique Ligands	SO4, TFA

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1WA7 \| pdb_00001wa7	Download File View File

SH3 DOMAIN OF HUMAN LYN TYROSINE KINASE IN COMPLEX WITH A HERPESVIRAL LIGAND

Bauer, F., Schweimer, K., Hoffmann, S., Roesch, P., Sticht, H.

(2002) Biochemistry 41: 5120

Released	2005-07-07
Method	SOLUTION NMR
Organisms	Homo sapiens Saimiriine gammaherpesvirus 2
Macromolecule	HYPOTHETICAL 28.7 KDA PROTEIN IN DHFR 3'REGION (ORF1) (protein) TYROSINE-PROTEIN KINASE LYN (protein)

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2BZ8 \| pdb_00002bz8	Download File View File

N-terminal Sh3 domain of CIN85 bound to Cbl-b peptide

Cardenes, N., Moncalian, G., Bravo, J.

(2005) Nat Struct Mol Biol 12: 972

Released	2005-10-05
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	SH3-DOMAIN KINASE BINDING PROTEIN 1 (protein) SIGNAL TRANSDUCTION PROTEIN CBL-B SH3-BINDING PROTEIN CBL-B, RING FINGER PROTEIN 56, CBL-B (protein)
Unique Ligands	NA

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2BZX \| pdb_00002bzx	Download File View File

Atomic model of CrkL-SH3C monomer

Harkiolaki, M., Gilbert, R.J., Jones, E.Y., Feller, S.M.

(2006) Structure 14: 1741

Released	2006-09-28
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Homo sapiens
Macromolecule	CRK-LIKE PROTEIN (protein)

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2BZY \| pdb_00002bzy	Download File View File

Homodimer of CrkL-SH3C domain

Harkiolaki, M., Gilbert, R.J., Jones, E.Y., Feller, S.M.

(2006) Structure 14: 1741

Released	2006-09-28
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Homo sapiens
Macromolecule	CRK-LIKE PROTEIN (protein)

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2K6D \| pdb_00002k6d	Download File View File

CIN85 Sh3-C domain in complex with ubiquitin

Forman-Kay, J., Bezsonova, I.

(2008) Biochemistry 47: 8937-8949

Released	2008-08-19
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	SH3 domain-containing kinase-binding protein 1 (protein) Ubiquitin (protein)

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1EFN \| pdb_00001efn	Download File View File

HIV-1 NEF PROTEIN IN COMPLEX WITH R96I MUTANT FYN SH3 DOMAIN

Lee, C.-H., Kuriyan, J.

(1996) Cell 85: 931-942

Released	1997-01-11
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Homo sapiens Human immunodeficiency virus 1
Macromolecule	FYN TYROSINE KINASE (protein) HIV-1 NEF PROTEIN (protein)
Unique Ligands	PBM

1 to 19 of 19 Structures

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RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.

1B07 | pdb_00001b07

CRK SH3 DOMAIN COMPLEXED WITH PEPTOID INHIBITOR

1BK2 | pdb_00001bk2

A-SPECTRIN SH3 DOMAIN D48G MUTANT

1E0L | pdb_00001e0l

FBP28WW domain from Mus musculus

1E6G | pdb_00001e6g

A-SPECTRIN SH3 DOMAIN A11V, V23L, M25I, V53I, V58L MUTANT

1E6H | pdb_00001e6h

A-SPECTRIN SH3 DOMAIN A11V, M25I, V44I, V58L MUTANTS

1H8K | pdb_00001h8k

A-SPECTRIN SH3 DOMAIN A11V, V23L, M25V, V53I, V58L MUTANT

1NEB | pdb_00001neb

SH3 DOMAIN FROM HUMAN NEBULIN, NMR, MINIMIZED AVERAGE STRUCTURE

1O7K | pdb_00001o7k

human p47 PX domain complex with sulphates

1UUE | pdb_00001uue

a-SPECTRIN SH3 DOMAIN (V44T, D48G MUTANT)

1V1C | pdb_00001v1c

Solution Structure of the SH3 domain of Obscurin

1W1F | pdb_00001w1f

SH3 DOMAIN OF HUMAN LYN TYROSINE KINASE

1W6X | pdb_00001w6x

SH3 domain of p40phox, component of the NADPH oxidase

1W70 | pdb_00001w70

SH3 domain of p40phox complexed with C-terminal polyProline region of p47phox

1WA7 | pdb_00001wa7

SH3 DOMAIN OF HUMAN LYN TYROSINE KINASE IN COMPLEX WITH A HERPESVIRAL LIGAND

2BZ8 | pdb_00002bz8

N-terminal Sh3 domain of CIN85 bound to Cbl-b peptide

2BZX | pdb_00002bzx

Atomic model of CrkL-SH3C monomer

2BZY | pdb_00002bzy

Homodimer of CrkL-SH3C domain

2K6D | pdb_00002k6d

CIN85 Sh3-C domain in complex with ubiquitin

1EFN | pdb_00001efn

HIV-1 NEF PROTEIN IN COMPLEX WITH R96I MUTANT FYN SH3 DOMAIN

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification

1B07 | pdb_00001b07

1BK2 | pdb_00001bk2

1E0L | pdb_00001e0l

1E6G | pdb_00001e6g

1E6H | pdb_00001e6h

1H8K | pdb_00001h8k

1NEB | pdb_00001neb

1O7K | pdb_00001o7k

1UUE | pdb_00001uue

1V1C | pdb_00001v1c

1W1F | pdb_00001w1f

1W6X | pdb_00001w6x

1W70 | pdb_00001w70

1WA7 | pdb_00001wa7

2BZ8 | pdb_00002bz8

2BZX | pdb_00002bzx

2BZY | pdb_00002bzy

2K6D | pdb_00002k6d

1EFN | pdb_00001efn