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235,458 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Structure Keywords HAS EXACT PHRASE "Hydrolase/RNA"

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Search Summary

This query matches 133 Structures.

Refinements

Structure Determination Methodology

experimental (133)

Scientific Name of Source Organism

	Homo sapiens (76)
	Mus musculus (30)
	Camelus dromedarius (17)
	Bos taurus (15)
	Ricinus communis (12)
	Lama glama (11)
	Vicugna pacos (11)
	Gallus gallus (10)
	Influenza A virus (4)
	Rattus norvegicus (4)

More...

Taxonomy

	Eukaryota (133)
	Riboviria (14)
	Bacteria (7)
	other sequences (2)

Experimental Method

	X-RAY DIFFRACTION (103)
	ELECTRON MICROSCOPY (30)

Polymer Entity Type

	Protein (133)
	RNA (2)

Refinement Resolution (Å)

	1.0 - 1.5 (6)
	1.5 - 2.0 (29)
	2.0 - 2.5 (28)
	2.5 - 3.0 (32)
	3.0 - 3.5 (18)
	3.5 - 4.0 (9)
	4.0 - 4.5 (5)
	> 4.5 (6)

Release Date

	1995 - 1999 (1)
	2000 - 2004 (5)
	2005 - 2009 (22)
	2010 - 2014 (29)
	2015 - 2019 (34)
	2020 - 2024 (42)

Enzyme Classification Name

	Hydrolases (131)
	Lyases (13)
	Transferases (11)

Membrane Protein Annotation

OPM (3)

Symmetry Type

	Asymmetric (99)
	Cyclic (23)
	Dihedral (11)
	Helical (1)

SCOP Classification

	All beta proteins (85)
	Alpha and beta proteins (a+b) (36)
	Alpha and beta proteins (a/b) (17)
	Artifacts (14)
	Small proteins (4)
	Multi-domain proteins (alpha and beta) (2)

AllSelected

1 to 25 of 133 Structures

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1BZQ \| pdb_00001bzq	Download File View File

COMPLEX OF A DROMEDARY SINGLE-DOMAIN VHH ANTIBODY FRAGMENT WITH RNASE A

Decanniere, K., Desmyter, A., Gahroudhi, M., Lauwereys, M., Muyldermans, S., Wyns, L.

(1999) Structure 7: 361-370

Released	1998-11-11
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Bos taurus Camelus dromedarius
Macromolecule	PROTEIN (ANTIBODY CAB-RN05) (protein) PROTEIN (RNASE A) (protein)
Unique Ligands	PO4

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1KXQ \| pdb_00001kxq	Download File View File

Camelid VHH Domain in Complex with Porcine Pancreatic alpha-Amylase

Desmyter, A., Spinelli, S., Payan, F., Lauwereys, M., Wyns, L., Muyldermans, S., Cambillau, C.

(2002) J Biological Chem 277: 23645-23650

Released	2002-06-19
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Camelus dromedarius Sus scrofa
Macromolecule	alpha-amylase, pancreatic (protein) antibody VHH fragment CABAMD9 (protein)
Unique Ligands	CA, CL

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1KXT \| pdb_00001kxt	Download File View File

Camelid VHH Domains in Complex with Porcine Pancreatic alpha-Amylase

Desmyter, A., Spinelli, S., Payan, F., Lauwereys, M., Wyns, L., Muyldermans, S., Cambillau, C.

(2002) J Biological Chem 277: 23645-23650

Released	2002-06-19
Method	X-RAY DIFFRACTION 2 Å
Organisms	Camelus dromedarius Sus scrofa
Macromolecule	ALPHA-AMYLASE, PANCREATIC (protein) IMMUNOGLOBULIN VHH FRAGMENT (protein)
Unique Ligands	CA, CL

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1KXV \| pdb_00001kxv	Download File View File

Camelid VHH Domains in Complex with Porcine Pancreatic alpha-Amylase

Desmyter, A., Spinelli, S., Payan, F., Lauwereys, M., Wyns, L., Muyldermans, S., Cambillau, C.

(2002) J Biological Chem 277: 23645-23650

Released	2002-06-19
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Camelus dromedarius Sus scrofa
Macromolecule	ALPHA-AMYLASE, PANCREATIC (protein) CAMELID VHH DOMAIN CAB10 (protein)

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1SQ2 \| pdb_00001sq2	Download File View File

Crystal Structure Analysis of the Nurse Shark New Antigen Receptor (NAR) Variable Domain in Complex With Lysozyme

Stanfield, R.L., Dooley, H., Flajnik, M.F., Wilson, I.A.

(2004) Science 305: 1770-1773

Released	2004-08-24
Method	X-RAY DIFFRACTION 1.45 Å
Organisms	Gallus gallus Ginglymostoma cirratum
Macromolecule	Lysozyme C (protein) novel antigen receptor (protein)
Unique Ligands	CL, EDO

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1T6V \| pdb_00001t6v	Download File View File

Crystal structure analysis of the nurse shark new antigen receptor (NAR) variable domain in complex with lysozyme

Stanfield, R.L., Dooley, H., Flajnik, M.F., Wilson, I.A.

(2004) Science 305: 1770-1773

Released	2004-08-24
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Gallus gallus Ginglymostoma cirratum
Macromolecule	Lysozyme C (protein) novel antigen receptor (protein)
Unique Ligands	CL

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1ZV5 \| pdb_00001zv5	Download File View File

Crystal structure of the variable domain of the camelid heavy-chain antibody D2-L29 in complex with hen egg white lysozyme

De Genst, E., Silence, K., Decanniere, K., Conrath, K., Loris, R., Kinne, J., Muyldermans, S., Wyns, L.

(2006) Proc Natl Acad Sci U S A 103: 4586-4591

Released	2006-04-04
Method	X-RAY DIFFRACTION 2 Å
Organisms	Camelus dromedarius Gallus gallus
Macromolecule	Lysozyme C (protein) immunoglobulin heavy chain antibody variable domain (protein)
Unique Ligands	PO4

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1ZVH \| pdb_00001zvh	Download File View File

Crystal structure of the VHH domain D2-L24 in complex with hen egg white lysozyme

De Genst, E., Silence, K., Decanniere, K., Conrath, K., Loris, R., Kinne, J., Muyldermans, S., Wyns, L.

(2006) Proc Natl Acad Sci U S A 103: 4586-4591

Released	2006-04-04
Method	X-RAY DIFFRACTION 1.5 Å
Organisms	Camelus dromedarius Gallus gallus
Macromolecule	Immunoglobulin heavy chain antibody variable domain (protein) Lysozyme C (protein)

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1ZVY \| pdb_00001zvy	Download File View File

Crystal structure of the VHH D3-L11 in complex with hen egg white lysozyme

De Genst, E., Silence, K., Decanniere, K., Conrath, K., Loris, R., Kinne, J., Muyldermans, S., Wyns, L.

(2006) Proc Natl Acad Sci U S A 103: 4586-4591

Released	2006-04-04
Method	X-RAY DIFFRACTION 1.63 Å
Organisms	Camelus dromedarius Gallus gallus
Macromolecule	Immunoglobulin heavy chain antibody variable domain (protein) Lysozyme C (protein)
Unique Ligands	GOL, PO4

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2AEQ \| pdb_00002aeq	Download File View File

An epidemiologically significant epitope of a 1998 influenza virus neuraminidase forms a highly hydrated interface in the NA-antibody complex.

Venkatramani, L., Bochkarev, A., Air, G.M.

(2006) J Mol Biology 356: 651-663

Released	2005-12-20
Method	X-RAY DIFFRACTION 3 Å
Organisms	Influenza A virus Mus musculus
Macromolecule	FAB heavy chain (protein) FAB light chain (protein) neuraminidase (protein)
Unique Ligands	MAN, NAG

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2NR6 \| pdb_00002nr6	Download File View File

Crystal structure of the complex of antibody and the allergen Bla g 2

Li, M., Gustchina, A., Wlodawer, A., Pomes, A., Wunschmann, S.

(2008) J Biological Chem 283: 22806-22814

Released	2008-02-19
Method	X-RAY DIFFRACTION 2.81 Å
Organisms	Blattella germanica Mus musculus
Macromolecule	Antibody heavy chain (protein) Antibody light chain (protein) Aspartic protease Bla g 2 (protein)
Unique Ligands	NAG, ZN
Unique branched monosaccharides	NAG

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2P42 \| pdb_00002p42	Download File View File

Complex of a camelid single-domain vhh antibody fragment with RNASE A at 1.8A resolution: SE3-mono-2 crystal form with three se-met sites (M34, M51, M83) in vhh scaffold

Tereshko, V., Uysal, S., Koide, A., Margalef, K., Koide, S., Kossiakoff, A.A.

(2008) Protein Sci 17: 1175-1187

Released	2008-03-11
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Bos taurus Camelus dromedarius
Macromolecule	ANTIBODY CAB-RN05 (protein) Ribonuclease pancreatic (protein)
Unique Ligands	MG

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2P43 \| pdb_00002p43	Download File View File

Complex of a camelid single-domain vhh antibody fragment with RNASE A at 1.65A resolution: SE3-mono-1 crystal form with three se-met sites (M34, M51, M83) in vhh scaffold

Tereshko, V., Uysal, S., Koide, A., Margalef, K., Koide, S., Kossiakoff, A.A.

(2008) Protein Sci 17: 1175-1187

Released	2008-03-11
Method	X-RAY DIFFRACTION 1.65 Å
Organisms	Bos taurus Camelus dromedarius
Macromolecule	ANTIBODY CAB-RN05 (protein) Ribonuclease pancreatic (protein)

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2P44 \| pdb_00002p44	Download File View File

Complex of a camelid single-domain vhh antibody fragment with RNASE A at 1.8A resolution: SE5A-mono-1 crystal form with five se-met sites (M34, M51, F68M, M83, L86M) in vhh scaffold

Tereshko, V., Uysal, S., Koide, A., Margalef, K., Koide, S., Kossiakoff, A.A.

(2008) Protein Sci 17: 1175-1187

Released	2008-03-11
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Bos taurus Camelus dromedarius
Macromolecule	ANTIBODY CAB-RN05 (protein) Ribonuclease pancreatic (protein)

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2P45 \| pdb_00002p45	Download File View File

Complex of a camelid single-domain vhh antibody fragment with RNASE A at 1.1A resolution: SE5B-ORTHO-1 crystal form with five se-met sites (L4M, M34, M51, F68M, M83) in vhh scaffold.

Tereshko, V., Uysal, S., Koide, A., Margalef, K., Koide, S., Kossiakoff, A.A.

(2008) Protein Sci 17: 1175-1187

Released	2008-03-11
Method	X-RAY DIFFRACTION 1.1 Å
Organisms	Bos taurus Camelus dromedarius
Macromolecule	ANTIBODY CAB-RN05 (protein) Ribonuclease pancreatic (protein)
Unique Ligands	SO4

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2P46 \| pdb_00002p46	Download File View File

Complex of a camelid single-domain vhh antibody fragment with RNASE A at 2.5A resolution: se5b-ortho-2 crystal form with five se-met sites (L4M, M34, M51, F68M, M83) in vhh scaffold.

Tereshko, V., Uysal, S., Koide, A., Margalef, K., Koide, S., Kossiakoff, A.A.

(2008) Protein Sci 17: 1175-1187

Released	2008-03-11
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Bos taurus Camelus dromedarius
Macromolecule	ANTIBODY CAB-RN05 (protein) Ribonuclease pancreatic (protein)
Unique Ligands	ZN

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2P47 \| pdb_00002p47	Download File View File

Complex of a camelid single-domain vhh antibody fragment with RNASE A at 2.5A resolution: SE5B-TRI crystal form with five se-met sites (L4M, M34, M51, F68M, M83) in vhh scaffold.

Tereshko, V., Uysal, S., Koide, A., Margalef, K., Koide, S., Kossiakoff, A.A.

(2008) Protein Sci 17: 1175-1187

Released	2008-03-11
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Bos taurus Camelus dromedarius
Macromolecule	ANTIBODY CAB-RN05 (protein) Ribonuclease pancreatic (protein)

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2P48 \| pdb_00002p48	Download File View File

Complex of a camelid single-domain vhh antibody fragment with RNASE A at 2.3A resolution: SE5B-tetra crystal form with five se-met sites (L4M, M34, M51, F68M, M83) in vhh scaffold.

Tereshko, V., Uysal, S., Koide, A., Margalef, K., Koide, S., Kossiakoff, A.A.

(2008) Protein Sci 17: 1175-1187

Released	2008-03-11
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Bos taurus Camelus dromedarius
Macromolecule	ANTIBODY CAB-RN05 (protein) Ribonuclease pancreatic (protein)
Unique Ligands	SO4

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2P49 \| pdb_00002p49	Download File View File

Complex of a camelid single-domain vhh antibody fragment with RNASE A at 1.4A resolution: native mono_1 crystal form

Tereshko, V., Uysal, S., Margalef, K., Koide, A., Kossiakoff, A.A., Koide, S.

(2007) J Mol Biology 373: 941-953

Released	2007-08-28
Method	X-RAY DIFFRACTION 1.38 Å
Organisms	Bos taurus Camelus dromedarius
Macromolecule	ANTIBODY CAB-RN05 (protein) Ribonuclease pancreatic (protein)
Unique Ligands	PO4

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2P4A \| pdb_00002p4a	Download File View File

X-ray structure of a camelid affinity matured single-domain vhh antibody fragment in complex with RNASE A

Tereshko, V., Koide, A., Uysal, S., Koide, S.

(2007) J Mol Biology 373: 941-953

Released	2007-08-28
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Bos taurus Camelus dromedarius
Macromolecule	ANTIBODY CAB-RN05 (protein) Ribonuclease pancreatic (protein)
Unique Ligands	SO4

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2R0K \| pdb_00002r0k	Download File View File

Protease domain of HGFA with inhibitor Fab58

Eigenbrot, C., Shia, S.

(2007) Proc Natl Acad Sci U S A 104: 19784-19789

Released	2007-12-25
Method	X-RAY DIFFRACTION 3.51 Å
Organisms	Homo sapiens
Macromolecule	Hepatocyte growth factor activator (protein) antibody heavy chain of Fab58, Fab portion only (protein) antibody light chain of Fab58 (protein)

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2R0L \| pdb_00002r0l	Download File View File

Short Form HGFA with Inhibitory Fab75

Eigenbrot, C., Shia, S.

(2007) Proc Natl Acad Sci U S A 104: 19784-19789

Released	2007-12-25
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Homo sapiens synthetic construct
Macromolecule	Hepatocyte growth factor activator (protein) antibody heavy chain, Fab portion only (protein) antibody light chain (protein)
Unique branched monosaccharides	BMA, NAG

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2WUB \| pdb_00002wub	Download File View File

Crystal structure of HGFA in complex with the allosteric non- inhibitory antibody Fab40.deltaTrp

Ganesan, R., Eigenbrot, C., Shia, S.

(2009) Structure 17: 1614

Released	2009-12-15
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Homo sapiens
Macromolecule	FAB FRAGMENT FAB40.DELTATRP HEAVY CHAIN (protein) FAB FRAGMENT FAB40.DELTATRP LIGHT CHAIN (protein) HEPATOCYTE GROWTH FACTOR ACTIVATOR LONG CHAIN (protein) HEPATOCYTE GROWTH FACTOR ACTIVATOR SHORT CHAIN (protein)
Unique branched monosaccharides	BMA, NAG

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3D9A \| pdb_00003d9a	Download File View File

High Resolution Crystal Structure Structure of HyHel10 Fab Complexed to Hen Egg Lysozyme

DeSantis, M.E., Li, M., Shanmuganathan, A., Acchione, M., Walter, R., Wlodawer, A., Smith-Gill, S.

(2009) Mol Immunol 47: 457-464

Released	2008-06-10
Method	X-RAY DIFFRACTION 1.2 Å
Organisms	Gallus gallus Mus musculus
Macromolecule	Heavy Chain of HyHel10 Antibody Fragment (Fab) (protein) Light Chain of HyHel10 Antibody Fragment (Fab) (protein) Lysozyme C (protein)

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3G3A \| pdb_00003g3a	Download File View File

Structure of a lamprey variable lymphocyte receptor in complex with a protein antigen

Deng, L., Velikovsky, C.A., Mariuzza, R.A.

(2009) Nat Struct Mol Biol 16: 725-730

Released	2009-06-23
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Gallus gallus Petromyzon marinus
Macromolecule	Lysozyme C (protein) Variable lymphocyte receptor VLRB.2D (protein)

1 to 25 of 133 Structures

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification

1BZQ | pdb_00001bzq

1KXQ | pdb_00001kxq

1KXT | pdb_00001kxt

1KXV | pdb_00001kxv

1SQ2 | pdb_00001sq2

1T6V | pdb_00001t6v

1ZV5 | pdb_00001zv5

1ZVH | pdb_00001zvh

1ZVY | pdb_00001zvy

2AEQ | pdb_00002aeq

2NR6 | pdb_00002nr6

2P42 | pdb_00002p42

2P43 | pdb_00002p43

2P44 | pdb_00002p44

2P45 | pdb_00002p45

2P46 | pdb_00002p46

2P47 | pdb_00002p47

2P48 | pdb_00002p48

2P49 | pdb_00002p49

2P4A | pdb_00002p4a

2R0K | pdb_00002r0k

2R0L | pdb_00002r0l

2WUB | pdb_00002wub

3D9A | pdb_00003d9a

3G3A | pdb_00003g3a