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234,440 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: PubMed ID = 30679383

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Search Summary

This query matches 10 Structures.

Refinements

Structure Determination Methodology

experimental (10)

Scientific Name of Source Organism

	Escherichia phage T7 (10)
	Escherichia coli (1)

Taxonomy

	Duplodnaviria (10)
	Bacteria (1)

Experimental Method

ELECTRON MICROSCOPY (10)

Polymer Entity Type

	DNA (10)
	Protein (10)
	RNA (4)

Refinement Resolution (Å)

	3.0 - 3.5 (1)
	3.5 - 4.0 (4)
	4.0 - 4.5 (3)
	> 4.5 (2)

Release Date

2015 - 2019 (10)

Enzyme Classification Name

	Hydrolases (10)
	Transferases (10)

Symmetry Type

Asymmetric (10)

AllSelected

1 to 10 of 10 Structures

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6N7I \| pdb_00006n7i	Download File View File

Structure of bacteriophage T7 E343Q mutant gp4 helicase-primase in complex with ssDNA, dTTP, AC dinucleotide and CTP (gp4(5)-DNA)

Gao, Y., Cui, Y., Zhou, Z., Yang, W.

(2019) Science 363:

Released	2019-03-06
Method	ELECTRON MICROSCOPY 3.2 Å
Organisms	Escherichia phage T7
Macromolecule	DNA primase/helicase (protein) DNA (25-MER) (nucleic acid)
Unique Ligands	MG, TTP

Explore in 3D

6N7N \| pdb_00006n7n	Download File View File

Structure of bacteriophage T7 E343Q mutant gp4 helicase-primase in complex with ssDNA, dTTP, AC dinucleotide and CTP (form I)

Gao, Y., Cui, Y., Zhou, Z., Yang, W.

(2019) Science 363:

Released	2019-03-06
Method	ELECTRON MICROSCOPY 3.5 Å
Organisms	Escherichia phage T7
Macromolecule	DNA primase/helicase (protein) DNA (5'-D(PTPTPTPTPTPTPTPTPTPTPTPTPTPTP*T)-3') (nucleic acid)
Unique Ligands	MG, TTP

Explore in 3D

6N7S \| pdb_00006n7s	Download File View File

Structure of bacteriophage T7 E343Q mutant gp4 helicase-primase in complex with ssDNA, dTTP, AC dinucleotide and CTP (form II)

Gao, Y., Cui, Y., Zhou, Z., Yang, W.

(2019) Science 363:

Released	2019-03-06
Method	ELECTRON MICROSCOPY 4.6 Å
Organisms	Escherichia phage T7
Macromolecule	DNA primase/helicase (protein) DNA (25-MER) (nucleic acid)
Unique Ligands	MG, TTP

Explore in 3D

6N7T \| pdb_00006n7t	Download File View File

Structure of bacteriophage T7 E343Q mutant gp4 helicase-primase in complex with ssDNA, dTTP, AC dinucleotide and CTP (form III)

Gao, Y., Cui, Y., Zhou, Z., Yang, W.

(2019) Science 363:

Released	2019-03-06
Method	ELECTRON MICROSCOPY 3.9 Å
Organisms	Escherichia phage T7
Macromolecule	DNA primase/helicase (protein) DNA (25-MER) (nucleic acid)
Unique Ligands	MG, TTP

Explore in 3D

6N7V \| pdb_00006n7v	Download File View File

Structure of bacteriophage T7 gp4 (helicase-primase, E343Q mutant) in complex with ssDNA, dTTP, AC dinucleotide, and CTP (from multiple lead complexes)

Gao, Y., Fox, T., Val, N., Yang, W.

(2019) Science 363:

Released	2019-03-06
Method	ELECTRON MICROSCOPY 3.8 Å
Organisms	Escherichia phage T7
Macromolecule	DNA primase/helicase (protein) DNA (93-MER) (nucleic acid)
Unique Ligands	MG, TTP

Explore in 3D

6N7W \| pdb_00006n7w	Download File View File

Structure of bacteriophage T7 leading-strand DNA polymerase (D5A/E7A)/Trx in complex with a DNA fork and incoming dTTP (from multiple lead complexes)

Gao, Y., Fox, T., Val, N., Yang, W.

(2019) Science 363:

Released	2019-03-06
Method	ELECTRON MICROSCOPY 4.5 Å
Organisms	Escherichia coli Escherichia phage T7
Macromolecule	DNA-directed DNA polymerase (protein) TrxA (protein) DNA (25-MER) (nucleic acid) DNA (77-MER) (nucleic acid)
Unique Ligands	MG, TTP

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6N9U \| pdb_00006n9u	Download File View File

Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) interacting with primase domains of two gp4 subunits bound to an RNA/DNA hybrid and dTTP (from LagS1)

Gao, Y., Fox, T., Val, N., Yang, W.

(2019) Science 363:

Released	2019-03-06
Method	ELECTRON MICROSCOPY 3.7 Å
Organisms	Escherichia phage T7
Macromolecule	DNA primase/helicase (protein) DNA-directed DNA polymerase (protein) DNA (44-MER) (nucleic acid) RNA (5'-R(APCPCPAPG)-D(P(DOC))-3') (nucleic acid)
Unique Ligands	MG, TTP, ZN

Explore in 3D

6N9V \| pdb_00006n9v	Download File View File

Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) and gp4 (helicase/primase) bound to DNA including RNA/DNA hybrid, and an incoming dTTP (LagS1)

Gao, Y., Fox, T., Val, N., Yang, W.

(2019) Science 363:

Released	2019-03-06
Method	ELECTRON MICROSCOPY 4 Å
Organisms	Escherichia phage T7
Macromolecule	DNA primase/helicase (protein) DNA-directed DNA polymerase (protein) Primer (nucleic acid) Template (nucleic acid)
Unique Ligands	MG, TTP, ZN

Explore in 3D

6N9W \| pdb_00006n9w	Download File View File

Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) and gp4 (helicase/primase) bound to DNA including RNA/DNA hybrid, and an incoming dTTP (LagS2)

Gao, Y., Cui, Y., Zhou, Z., Yang, W.

(2019) Science 363:

Released	2019-03-06
Method	ELECTRON MICROSCOPY 4 Å
Organisms	Escherichia phage T7
Macromolecule	DNA primase/helicase (protein) DNA-directed DNA polymerase (protein) Primer (nucleic acid) Template (nucleic acid)
Unique Ligands	MG, TTP, ZN

Explore in 3D

6N9X \| pdb_00006n9x	Download File View File

Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) and gp4 (helicase/primase) bound to DNA including RNA/DNA hybrid, and an incoming dTTP (LagS3)

Gao, Y., Fox, T., Val, N., Yang, W.

(2019) Science 363:

Released	2019-03-06
Method	ELECTRON MICROSCOPY 4.1 Å
Organisms	Escherichia phage T7
Macromolecule	DNA primase/helicase (protein) DNA-directed DNA polymerase (protein) Primer (nucleic acid) Template (nucleic acid)
Unique Ligands	MG, TTP, ZN

1 to 10 of 10 Structures

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RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.

6N7I | pdb_00006n7i

Structure of bacteriophage T7 E343Q mutant gp4 helicase-primase in complex with ssDNA, dTTP, AC dinucleotide and CTP (gp4(5)-DNA)

6N7N | pdb_00006n7n

Structure of bacteriophage T7 E343Q mutant gp4 helicase-primase in complex with ssDNA, dTTP, AC dinucleotide and CTP (form I)

6N7S | pdb_00006n7s

Structure of bacteriophage T7 E343Q mutant gp4 helicase-primase in complex with ssDNA, dTTP, AC dinucleotide and CTP (form II)

6N7T | pdb_00006n7t

Structure of bacteriophage T7 E343Q mutant gp4 helicase-primase in complex with ssDNA, dTTP, AC dinucleotide and CTP (form III)

6N7V | pdb_00006n7v

Structure of bacteriophage T7 gp4 (helicase-primase, E343Q mutant) in complex with ssDNA, dTTP, AC dinucleotide, and CTP (from multiple lead complexes)

6N7W | pdb_00006n7w

Structure of bacteriophage T7 leading-strand DNA polymerase (D5A/E7A)/Trx in complex with a DNA fork and incoming dTTP (from multiple lead complexes)

6N9U | pdb_00006n9u

Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) interacting with primase domains of two gp4 subunits bound to an RNA/DNA hybrid and dTTP (from LagS1)

6N9V | pdb_00006n9v

Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) and gp4 (helicase/primase) bound to DNA including RNA/DNA hybrid, and an incoming dTTP (LagS1)

6N9W | pdb_00006n9w

Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) and gp4 (helicase/primase) bound to DNA including RNA/DNA hybrid, and an incoming dTTP (LagS2)

6N9X | pdb_00006n9x

Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) and gp4 (helicase/primase) bound to DNA including RNA/DNA hybrid, and an incoming dTTP (LagS3)

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type

6N7I | pdb_00006n7i

6N7N | pdb_00006n7n

6N7S | pdb_00006n7s

6N7T | pdb_00006n7t

6N7V | pdb_00006n7v

6N7W | pdb_00006n7w

6N9U | pdb_00006n9u

6N9V | pdb_00006n9v

6N9W | pdb_00006n9w

6N9X | pdb_00006n9x