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234,440 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Enzyme Classification Number = 2.7.7.56

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Search Summary

This query matches 4 Structures.

Refinements

Structure Determination Methodology

experimental (4)

Scientific Name of Source Organism

	Klebsiella pneumoniae (2)
	Escherichia coli K-12 (1)
	Pseudomonas aeruginosa PAO1 (1)

Taxonomy

Bacteria (4)

Experimental Method

X-RAY DIFFRACTION (4)

Polymer Entity Type

Protein (4)

Refinement Resolution (Å)

	1.0 - 1.5 (1)
	1.5 - 2.0 (2)
	2.0 - 2.5 (1)

Release Date

	2015 - 2019 (2)
	2020 - 2024 (2)

Enzyme Classification Name

Hydrolases (4)

Symmetry Type

Asymmetric (4)

SCOP Classification

	Multi-domain proteins (alpha and beta) (4)
	Alpha and beta proteins (a+b) (1)

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1 to 4 of 4 Structures

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6B1J \| pdb_00006b1j	Download File View File

Crystal structure KPC-2 beta-lactamase complexed with WCK 5107 by soaking

van den Akker, F., Nguyen, N.Q.

(2018) J Med Chem 61: 4067-4086

Released	2018-08-01
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Klebsiella pneumoniae
Macromolecule	Carbapenem-hydrolyzing beta-lactamase KPC (protein)
Unique Ligands	C8V, CIT, EDO

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6B1W \| pdb_00006b1w	Download File View File

Crystal structure KPC-2 beta-lactamase complexed with WCK 5107 by co-crystallization

van den Akker, F., Nguyen, N.Q.

(2018) J Med Chem 61: 4067-4086

Released	2018-08-01
Method	X-RAY DIFFRACTION 1.73 Å
Organisms	Klebsiella pneumoniae
Macromolecule	Carbapenem-hydrolyzing beta-lactamase KPC (protein)
Unique Ligands	C8V, CL, SO4

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6T5Y \| pdb_00006t5y	Download File View File

Crystal structure of AmpC from E.coli with Zidebactam (WCK 5107)

Lang, P.A., Leissing, T.M., Schofield, C.J., Brem, J.

(2021) Antimicrob Agents Chemother 65:

Released	2020-11-18
Method	X-RAY DIFFRACTION 1.3 Å
Organisms	Escherichia coli K-12
Macromolecule	Beta-lactamase (protein)
Unique Ligands	C8V, CL, PEG, ZN

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7KIW \| pdb_00007kiw	Download File View File

Crystal structure of Pseudomonas aeruginosa PBP3 in complex with zidebactam

van den Akker, F., Kumar, V.

(2021) mBio 12:

Released	2021-01-13
Method	X-RAY DIFFRACTION 2.49 Å
Organisms	Pseudomonas aeruginosa PAO1
Macromolecule	Peptidoglycan D,D-transpeptidase FtsI (protein)
Unique Ligands	C8V