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234,440 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Gene Name = "YOP51"

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Search Summary

This query matches 20 Structures.

Refinements

Structure Determination Methodology

experimental (20)

Scientific Name of Source Organism

	Yersinia enterocolitica (17)
	Yersinia enterocolitica (type O:9) (3)
	Yersinia pestis (1)

Taxonomy

Bacteria (20)

Experimental Method

X-RAY DIFFRACTION (20)

Polymer Entity Type

Protein (20)

Refinement Resolution (Å)

	1.0 - 1.5 (5)
	1.5 - 2.0 (5)
	2.0 - 2.5 (5)
	2.5 - 3.0 (4)
	3.0 - 3.5 (1)

Release Date

	1990 - 1994 (1)
	1995 - 1999 (3)
	2005 - 2009 (9)
	2010 - 2014 (2)
	2015 - 2019 (4)
	2020 - 2024 (1)

Enzyme Classification Name

Hydrolases (20)

Symmetry Type

	Asymmetric (19)
	Cyclic (1)

SCOP Classification

	Alpha and beta proteins (a/b) (19)
	Alpha and beta proteins (a+b) (1)

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1 to 20 of 20 Structures

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1XXP \| pdb_00001xxp	Download File View File

Yersinia YopH (residues 163-468) C403S binds phosphotyrosyl peptide at two sites

Ivanov, M.I., Stuckey, J.A., Schubert, H.L., Saper, M.A., Bliska, J.B.

(2005) Mol Microbiol 55: 1346-1356

Released	2005-03-22
Method	X-RAY DIFFRACTION 3 Å
Organisms	Yersinia enterocolitica
Macromolecule	Hexapeptide ASP-ALA-ASP-GLU-PTR-CLE (protein) Protein-tyrosine phosphatase yopH (protein)

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1XXV \| pdb_00001xxv	Download File View File

Yersinia YopH (residues 163-468) binds phosphonodifluoromethyl-Phe containing hexapeptide at two sites

Ivanov, M.I., Stuckey, J.A., Schubert, H.L., Saper, M.A., Bliska, J.B.

(2005) Mol Microbiol 55: 1346-1356

Released	2005-03-22
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Yersinia enterocolitica
Macromolecule	Epidermal growth factor receptor derived peptide (protein) Protein-tyrosine phosphatase yopH (protein)

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1YPT \| pdb_00001ypt	Download File View File

CRYSTAL STRUCTURE OF YERSINIA PROTEIN TYROSINE PHOSPHATASE AT 2.5 ANGSTROMS AND THE COMPLEX WITH TUNGSTATE

Stuckey, J.A., Schubert, H.L., Fauman, E.B., Zhang, Z.-Y., Dixon, J.E., Saper, M.A.

(1994) Nature 370: 571-575

Released	1994-12-20
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Yersinia enterocolitica
Macromolecule	PROTEIN-TYROSINE PHOSPHATASE YERSINIA (CATALYTIC DOMAIN) (protein)

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1YTN \| pdb_00001ytn	Download File View File

HYDROLASE

Yuvaniyama, C., Fauman, E.B., Saper, M.A.

(1996) J Biological Chem 271: 18780-18788

Released	1996-11-08
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Yersinia enterocolitica
Macromolecule	YERSINIA PROTEIN TYROSINE PHOSPHATASE (protein)
Unique Ligands	NO3

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1YTS \| pdb_00001yts	Download File View File

A LIGAND-INDUCED CONFORMATIONAL CHANGE IN THE YERSINIA PROTEIN TYROSINE PHOSPHATASE

Schubert, H.L., Stuckey, J.A., Fauman, E.B., Dixon, J.E., Saper, M.A.

(1995) Protein Sci 4: 1904-1913

Released	1995-07-10
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Yersinia enterocolitica
Macromolecule	YERSINIA PROTEIN TYROSINE PHOSPHATASE (protein)
Unique Ligands	SO4

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1YTW \| pdb_00001ytw	Download File View File

YERSINIA PTPASE COMPLEXED WITH TUNGSTATE

Fauman, E.B., Schubert, H.L., Saper, M.A.

(1996) J Biological Chem 271: 18780-18788

Released	1996-11-08
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Yersinia enterocolitica
Macromolecule	YERSINIA PROTEIN TYROSINE PHOSPHATASE (protein)
Unique Ligands	SO4, WO4

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2I42 \| pdb_00002i42	Download File View File

Crystal structure of Yersinia protein tyrosine phosphatase complexed with vanadate, a transition state analogue

Vijayalakshmi, J., Saper, M.A.

To be published

Released	2006-09-19
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Yersinia enterocolitica
Macromolecule	Tyrosine-protein phosphatase (protein)
Unique Ligands	VO4

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3BLT \| pdb_00003blt	Download File View File

Crystal structures of YopH complexed with PVSN and PVS, inhibitors of YopH which co-valent bind to Cys of active site

Liu, S., Zhang, Z.-Y.

(2008) J Am Chem Soc 130: 8251-8260

Released	2009-02-10
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Yersinia enterocolitica
Macromolecule	Tyrosine-protein phosphatase yopH (protein)
Unique Ligands	PSY

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3BLU \| pdb_00003blu	Download File View File

crystal structure YopH complexed with inhibitor PVS

Liu, S., Zhang, Z.-Y.

(2008) J Am Chem Soc 130: 8251-8260

Released	2008-10-21
Method	X-RAY DIFFRACTION 2 Å
Organisms	Yersinia enterocolitica
Macromolecule	Tyrosine-protein phosphatase yopH (protein)
Unique Ligands	PVS

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3BM8 \| pdb_00003bm8	Download File View File

crystal structure of YopH mutant D356A complexed with irreversible inhibitor PVSN

Zhang, Z.Y., Liu, S.J.

(2008) J Am Chem Soc 130: 8251-8260

Released	2008-06-17
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Yersinia enterocolitica
Macromolecule	Tyrosine-protein phosphatase yopH (protein)
Unique Ligands	PSY

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3F99 \| pdb_00003f99	Download File View File

W354F Yersinia enterocolitica PTPase apo form

Brandao, T.A.S., Robinson, H., Johnson, S.J., Hengge, A.C.

(2009) J Am Chem Soc 131: 778-786

Released	2009-01-20
Method	X-RAY DIFFRACTION 1.65 Å
Organisms	Yersinia enterocolitica (type O:9)
Macromolecule	Tyrosine-protein phosphatase yopH (protein)
Unique Ligands	TRS

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3F9A \| pdb_00003f9a	Download File View File

W354F Yersinia enterocolitica PTPase complexed with tungstate

Brandao, T.A.S., Robinson, H., Johnson, S.J., Hengge, A.C.

(2009) J Am Chem Soc 131: 778-786

Released	2009-01-20
Method	X-RAY DIFFRACTION 1.69 Å
Organisms	Yersinia enterocolitica (type O:9)
Macromolecule	Tyrosine-protein phosphatase yopH (protein)
Unique Ligands	WO4

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3F9B \| pdb_00003f9b	Download File View File

W354F Yersinia enterocolitica PTPase complexed with divanadate

Brandao, T.A.S., Robinson, H., Johnson, S.J., Hengge, A.C.

(2009) J Am Chem Soc 131: 778-786

Released	2009-01-20
Method	X-RAY DIFFRACTION 1.42 Å
Organisms	Yersinia enterocolitica (type O:9)
Macromolecule	Tyrosine-protein phosphatase yopH (protein)
Unique Ligands	GOL, PDV, VO4

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3U96 \| pdb_00003u96	Download File View File

Crystal Structure of YopHQ357F(Catalytic Domain, Residues 163-468) in complex with pNCS

Ho, M.C., Ke, S.

(2012) J Phys Chem B 116: 6166-6176

Released	2012-08-29
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Yersinia enterocolitica
Macromolecule	Tyrosine-protein phosphatase yopH (protein)
Unique Ligands	CSN, SO4

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4GF3 \| pdb_00004gf3	Download File View File

Structure of a SycH-YopH Chaperone-Effector Complex

Stebbins, C.E., Vujanac, M.

(2013) Acta Crystallogr D Biol Crystallogr 69: 546-554

Released	2013-03-27
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Yersinia enterocolitica Yersinia pestis
Macromolecule	Putative yopH targeting protein (protein) Tyrosine-protein phosphatase yopH (protein)

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4YAA \| pdb_00004yaa	Download File View File

YopH W354Y Yersinia enterocolitica PTPase apo form

Moise, G.E., Johnson, S.J., Hengge, A.C.

(2015) Biochemistry 54: 6490-6500

Released	2015-10-28
Method	X-RAY DIFFRACTION 1.05 Å
Organisms	Yersinia enterocolitica
Macromolecule	Tyrosine-protein phosphatase YopH (protein)
Unique Ligands	ACT, SO4

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4Z6B \| pdb_00004z6b	Download File View File

YopH W354H Yersinia enterocolitica PTPase in the apo form

Moise, G.E., Johnson, S.J., Hengge, A.C.

(2015) Biochemistry 54: 6490-6500

Released	2015-10-28
Method	X-RAY DIFFRACTION 1.2 Å
Organisms	Yersinia enterocolitica
Macromolecule	Tyrosine-protein phosphatase YopH (protein)
Unique Ligands	ACT, GOL

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4ZI4 \| pdb_00004zi4	Download File View File

YopH W354H Yersinia enterocolitica PTPase bond with Divanadate glycerol ester in the active site

Moise, G.E., Johnson, S.J., Hengge, A.C.

(2015) Biochemistry 54: 6490-6500

Released	2015-10-28
Method	X-RAY DIFFRACTION 1.121 Å
Organisms	Yersinia enterocolitica
Macromolecule	Tyrosine-protein phosphatase YopH (protein)
Unique Ligands	DVG, VO4

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4ZN5 \| pdb_00004zn5	Download File View File

YopH W354Y Yersinia enterocolitica PTPase bond with Divanadate glycerol ester in the active site

Moise, G.E., Johnson, S.J., Hengge, A.C.

(2015) Biochemistry 54: 6490-6500

Released	2015-10-28
Method	X-RAY DIFFRACTION 1.12 Å
Organisms	Yersinia enterocolitica
Macromolecule	Tyrosine-protein phosphatase YopH (protein)
Unique Ligands	ACT, DVG, GOL, VO4

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6XFT \| pdb_00006xft	Download File View File

Crystal Structure of the Cys-NO Modified YopH Tyrosine Phosphatase

Fernandes, R., Pereira, H.M., Thiemann, O., Terenzi, H.

(2022) Biochim Biophys Acta Proteins Proteom 1870: 140754-140754

Released	2021-06-23
Method	X-RAY DIFFRACTION 1.78 Å
Organisms	Yersinia enterocolitica
Macromolecule	Tyrosine-protein phosphatase YopH (protein)

1 to 20 of 20 Structures

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RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.

1XXP | pdb_00001xxp

Yersinia YopH (residues 163-468) C403S binds phosphotyrosyl peptide at two sites

1XXV | pdb_00001xxv

Yersinia YopH (residues 163-468) binds phosphonodifluoromethyl-Phe containing hexapeptide at two sites

1YPT | pdb_00001ypt

CRYSTAL STRUCTURE OF YERSINIA PROTEIN TYROSINE PHOSPHATASE AT 2.5 ANGSTROMS AND THE COMPLEX WITH TUNGSTATE

1YTN | pdb_00001ytn

HYDROLASE

1YTS | pdb_00001yts

A LIGAND-INDUCED CONFORMATIONAL CHANGE IN THE YERSINIA PROTEIN TYROSINE PHOSPHATASE

1YTW | pdb_00001ytw

YERSINIA PTPASE COMPLEXED WITH TUNGSTATE

2I42 | pdb_00002i42

Crystal structure of Yersinia protein tyrosine phosphatase complexed with vanadate, a transition state analogue

3BLT | pdb_00003blt

Crystal structures of YopH complexed with PVSN and PVS, inhibitors of YopH which co-valent bind to Cys of active site

3BLU | pdb_00003blu

crystal structure YopH complexed with inhibitor PVS

3BM8 | pdb_00003bm8

crystal structure of YopH mutant D356A complexed with irreversible inhibitor PVSN

3F99 | pdb_00003f99

W354F Yersinia enterocolitica PTPase apo form

3F9A | pdb_00003f9a

W354F Yersinia enterocolitica PTPase complexed with tungstate

3F9B | pdb_00003f9b

W354F Yersinia enterocolitica PTPase complexed with divanadate

3U96 | pdb_00003u96

Crystal Structure of YopHQ357F(Catalytic Domain, Residues 163-468) in complex with pNCS

4GF3 | pdb_00004gf3

Structure of a SycH-YopH Chaperone-Effector Complex

4YAA | pdb_00004yaa

YopH W354Y Yersinia enterocolitica PTPase apo form

4Z6B | pdb_00004z6b

YopH W354H Yersinia enterocolitica PTPase in the apo form

4ZI4 | pdb_00004zi4

YopH W354H Yersinia enterocolitica PTPase bond with Divanadate glycerol ester in the active site

4ZN5 | pdb_00004zn5

YopH W354Y Yersinia enterocolitica PTPase bond with Divanadate glycerol ester in the active site

6XFT | pdb_00006xft

Crystal Structure of the Cys-NO Modified YopH Tyrosine Phosphatase

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Scientific Name of Source Organism

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Enzyme Classification Name

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1XXP | pdb_00001xxp

1XXV | pdb_00001xxv

1YPT | pdb_00001ypt

1YTN | pdb_00001ytn

1YTS | pdb_00001yts

1YTW | pdb_00001ytw

2I42 | pdb_00002i42

3BLT | pdb_00003blt

3BLU | pdb_00003blu

3BM8 | pdb_00003bm8

3F99 | pdb_00003f99

3F9A | pdb_00003f9a

3F9B | pdb_00003f9b

3U96 | pdb_00003u96

4GF3 | pdb_00004gf3

4YAA | pdb_00004yaa

4Z6B | pdb_00004z6b

4ZI4 | pdb_00004zi4

4ZN5 | pdb_00004zn5

6XFT | pdb_00006xft