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234,136 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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Search Summary

This query matches 886 Polymer Entities.

Refinements

Structure Determination Methodology

experimental (886)

Scientific Name of Source Organism

	Homo sapiens (695)
	Mus musculus (28)
	synthetic construct (12)
	Mycobacterium tuberculosis H37Rv (9)
	Rattus norvegicus (8)
	Agrobacterium fabrum str. C58 (5)
	Saccharomyces cerevisiae (5)
	Alphapolyomavirus mauratus (4)
	Arabidopsis (4)
	Escherichia coli str. K-12 substr. MG1655 (4)

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Taxonomy

	Eukaryota (719)
	Eukaryota (eukaryotes) (43)
	Bacteria (38)
	other sequences (12)
	Monodnaviria (7)
	Duplodnaviria (5)
	Riboviria (3)
	Varidnaviria (1)

Experimental Method

	X-RAY DIFFRACTION (816)
	SOLUTION NMR (50)
	ELECTRON MICROSCOPY (20)

Polymer Entity Type

Protein (886)

Refinement Resolution (Å)

	0.5 - 1.0 (1)
	1.0 - 1.5 (36)
	1.5 - 2.0 (199)
	2.0 - 2.5 (324)
	2.5 - 3.0 (209)
	3.0 - 3.5 (57)
	3.5 - 4.0 (8)
	4.0 - 4.5 (2)

Release Date

	1990 - 1994 (6)
	1995 - 1999 (46)
	2000 - 2004 (56)
	2005 - 2009 (127)
	2010 - 2014 (186)
	2015 - 2019 (219)
	2020 - 2024 (239)
	2025 - 2029 (7)

Enzyme Classification Name

	Transferases (606)
	Isomerases (43)
	Hydrolases (16)
	Ligases (4)

Membrane Protein Annotation

	OPM (3)
	mpstruc (1)

Symmetry Type

	Asymmetric (792)
	Cyclic (119)
	Dihedral (8)

SCOP Classification

	Alpha and beta proteins (a+b) (409)
	Artifacts (112)
	All beta proteins (37)
	All alpha proteins (15)
	Multi-domain proteins (alpha and beta) (13)
	Alpha and beta proteins (a/b) (1)

AllSelected

1 to 25 of 886 Polymer Entities

Page 1 of 36

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1A07: Entity 2	Download File View File

C-SRC (SH2 DOMAIN) COMPLEXED WITH ACE-MALONYL TYR-GLU-(N,N-DIPENTYL AMINE)

Shewchuk, L., Jordan, S.

(1997) Biochemistry 36: 6283-6293

Released	1998-04-08
Method	X-RAY DIFFRACTION 2.2 Å
Chain IDs	B [auth C], D
Macromolecule	ACE-MALONYL TYR-GLU-(N,N-DIPENTYL AMINE)

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1A1B: Entity 2	Download File View File

C-SRC (SH2 DOMAIN) COMPLEXED WITH ACE-PHOSPHOTYR-GLU-(N,N-DIPENTYL AMINE)

Shewchuk, L., Jordan, S.

(1997) Biochemistry 36: 6283-6293

Released	1998-04-08
Method	X-RAY DIFFRACTION 2.2 Å
Chain IDs	B [auth C], D
Macromolecule	ACE-PHOSPHOTYR-GLU-(N,N-DIPENTYL AMINE)

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1A1C: Entity 2	Download File View File

C-SRC (SH2 DOMAIN) COMPLEXED WITH ACE-PHOSPHOTYR-GLU-(N-ME(-(CH2)3-CYCLOPENTYL))

Shewchuk, L., Jordan, S.

(1997) Biochemistry 36: 6283-6293

Released	1998-04-08
Method	X-RAY DIFFRACTION 2.4 Å
Chain IDs	C, D
Macromolecule	ACE-PHOSPHOTYR-GLU-(N-ME(-(CH2)3-CYCLOPENTYL))

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1A1E: Entity 2	Download File View File

C-SRC (SH2 DOMAIN) COMPLEXED WITH ACE-PHOSPHOTYR-GLU-(3-BUTYLPIPERIDINE)

Shewchuk, L., Jordan, S.

(1997) Biochemistry 36: 6283-6293

Released	1998-04-08
Method	X-RAY DIFFRACTION 2.2 Å
Chain IDs	C, D
Macromolecule	ACE-PHOSPHOTYR-GLU-(3-BUTYLPIPERIDINE)

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1A31: Entity 3	Download File View File

HUMAN RECONSTITUTED DNA TOPOISOMERASE I IN COVALENT COMPLEX WITH A 22 BASE PAIR DNA DUPLEX

Redinbo, M.R., Stewart, L., Kuhn, P., Champoux, J.J., Hol, W.G.J.

(1998) Science 279: 1504-1513

Released	1998-08-28
Method	X-RAY DIFFRACTION 2.1 Å
Chain ID	C [auth A]
Organism	Homo sapiens
Macromolecule	PROTEIN (TOPOISOMERASE I)

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1A81: Entity 2	Download File View File

CRYSTAL STRUCTURE OF THE TANDEM SH2 DOMAIN OF THE SYK KINASE BOUND TO A DUALLY TYROSINE-PHOSPHORYLATED ITAM

Fuetterer, K., Waksman, G.

(1998) J Mol Biology 281: 523-537

Released	1998-10-21
Method	X-RAY DIFFRACTION 3 Å
Chain IDs	B, J, D, F, H
Organism	Homo sapiens
Macromolecule	T-CELL SURFACE GLYCOPROTEIN CD3 EPSILON CHAIN

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1AD5: Entity 1	Download File View File

SRC FAMILY KINASE HCK-AMP-PNP COMPLEX

Sicheri, F., Moarefi, I., Kuriyan, J.

(1997) Nature 385: 602-609

Released	1997-05-15
Method	X-RAY DIFFRACTION 2.6 Å
Chain IDs	A, B
Organism	Homo sapiens
Macromolecule	HAEMATOPOETIC CELL KINASE HCK

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1AOT: Entity 2	Download File View File

NMR STRUCTURE OF THE FYN SH2 DOMAIN COMPLEXED WITH A PHOSPHOTYROSYL PEPTIDE, MINIMIZED AVERAGE STRUCTURE

Mulhern, T.D., Shaw, G.L., Morton, C.J., Day, A.J., Campbell, I.D.

(1997) Structure 5: 1313-1323

Released	1998-01-14
Method	SOLUTION NMR
Chain ID	B [auth P]
Organism	Alphapolyomavirus mauratus
Macromolecule	PHOSPHOTYROSYL PEPTIDE

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1AOU: Entity 2	Download File View File

NMR STRUCTURE OF THE FYN SH2 DOMAIN COMPLEXED WITH A PHOSPHOTYROSYL PEPTIDE, 22 STRUCTURES

Mulhern, T.D., Shaw, G.L., Morton, C.J., Day, A.J., Campbell, I.D.

(1997) Structure 5: 1313-1323

Released	1998-01-14
Method	SOLUTION NMR
Chain ID	B [auth P]
Organism	Alphapolyomavirus mauratus
Macromolecule	PHOSPHOTYROSYL PEPTIDE

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1AYA: Entity 2	Download File View File

CRYSTAL STRUCTURES OF PEPTIDE COMPLEXES OF THE AMINO-TERMINAL SH2 DOMAIN OF THE SYP TYROSINE PHOSPHATASE

Lee, C.-H., Kuriyan, J.

(1994) Structure 2: 423-438

Released	1994-08-31
Method	X-RAY DIFFRACTION 2.05 Å
Chain IDs	B [auth P], D [auth Q]
Organism	Mus musculus
Macromolecule	PEPTIDE PDGFR-1009

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1AYB: Entity 2	Download File View File

CRYSTAL STRUCTURES OF PEPTIDE COMPLEXES OF THE AMINO-TERMINAL SH2 DOMAIN OF THE SYP TYROSINE PHOSPHATASE

Lee, C.-H., Kuriyan, J.

(1994) Structure 2: 423-438

Released	1994-08-31
Method	X-RAY DIFFRACTION 3 Å
Chain ID	B [auth P]
Organism	Mus musculus
Macromolecule	PEPTIDE IRS-1-895

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1AYC: Entity 2	Download File View File

CRYSTAL STRUCTURES OF PEPTIDE COMPLEXES OF THE AMINO-TERMINAL SH2 DOMAIN OF THE SYP TYROSINE PHOSPHATASE

Lee, C.-H., Kuriyan, J.

(1994) Structure 2: 423-438

Released	1994-08-31
Method	X-RAY DIFFRACTION 2.3 Å
Chain ID	B [auth P]
Organism	Mus musculus
Macromolecule	PEPTIDE PDGFR-740

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1BF5: Entity 3	Download File View File

TYROSINE PHOSPHORYLATED STAT-1/DNA COMPLEX

Kuriyan, J., Zhao, Y., Chen, X., Vinkemeier, U., Jeruzalmi, D., Darnell Jr., J.E.

(1998) Cell 93: 827-839

Released	1998-08-12
Method	X-RAY DIFFRACTION 2.9 Å
Chain ID	C [auth A]
Organism	Homo sapiens
Macromolecule	SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 1-ALPHA/BETA

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1BG1: Entity 2	Download File View File

TRANSCRIPTION FACTOR STAT3B/DNA COMPLEX

Becker, S., Groner, B., Muller, C.W.

(1998) Nature 394: 145-151

Released	1999-01-13
Method	X-RAY DIFFRACTION 2.25 Å
Chain ID	B [auth A]
Organism	Mus musculus
Macromolecule	PROTEIN (TRANSCRIPTION FACTOR STAT3B)

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1BM2: Entity 2	Download File View File

GRB2-SH2 DOMAIN IN COMPLEX WITH CYCLO-[N-ALPHA-ACETYL-L-THI ALYSYL-O-PHOSPHOTYROSYL-VALYL-ASPARAGYL-VALYL-PROLYL] (PKF273-791)

Rondeau, J.M., Zurini, M.

(1999) J Med Chem 42: 971-980

Released	1998-08-05
Method	X-RAY DIFFRACTION 2.1 Å
Chain ID	B [auth L]
Macromolecule	PROTEIN (PKF273-791)

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1BMB: Entity 2	Download File View File

GRB2-SH2 DOMAIN IN COMPLEX WITH KPFY*VNVEF (PKF270-974)

Rondeau, J.M., Zurini, M.

(1999) J Med Chem 42: 971-980

Released	1998-07-29
Method	X-RAY DIFFRACTION 1.8 Å
Chain ID	B [auth I]
Macromolecule	PROTEIN (PKF270-974)

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1CM8: Entity 1	Download File View File

PHOSPHORYLATED MAP KINASE P38-GAMMA

Bellon, S., Fitzgibbon, M.J., Fox, T., Hsiao, H.M., Wilson, K.P.

(1999) Structure 7: 1057-1065

Released	2000-05-17
Method	X-RAY DIFFRACTION 2.4 Å
Chain IDs	A, B
Organism	Homo sapiens
Macromolecule	PHOSPHORYLATED MAP KINASE P38-GAMMA

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1CRX: Entity 5	Download File View File

CRE RECOMBINASE/DNA COMPLEX REACTION INTERMEDIATE I

Guo, F., Gopaul, D.N., Van Duyne, G.D.

(1997) Nature 389: 40-46

Released	1998-10-14
Method	X-RAY DIFFRACTION 2.4 Å
Chain ID	F [auth B]
Organism	Punavirus P1
Macromolecule	Cre recombinase

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1CSY: Entity 2	Download File View File

SYK TYROSINE KINASE C-TERMINAL SH2 DOMAIN COMPLEXED WITH A PHOSPHOPEPTIDEFROM THE GAMMA CHAIN OF THE HIGH AFFINITY IMMUNOGLOBIN G RECEPTOR, NMR

Narula, S.S., Yuan, R.W., Adams, S.E., Green, O.M., Green, J., Phillips, T.B., Zydowsky, L.D., Botfield, M.C., Hatada, M.H., Laird, E.R., Zoller, M.J., Karas, J.L., Dalgarno, D.C.

(1995) Structure 3: 1061-1073

Released	1996-11-08
Method	SOLUTION NMR
Chain ID	B
Organism	Homo sapiens
Macromolecule	ACETYL-THR-PTR-GLU-THR-LEU-NH2

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1CSZ: Entity 2	Download File View File

SYK TYROSINE KINASE C-TERMINAL SH2 DOMAIN COMPLEXED WITH A PHOSPHOPEPTIDEFROM THE GAMMA CHAIN OF THE HIGH AFFINITY IMMUNOGLOBIN G RECEPTOR, NMR

Narula, S.S., Yuan, R.W., Adams, S.E., Green, O.M., Green, J., Phillips, T.B., Zydowsky, L.D., Botfield, M.C., Hatada, M.H., Laird, E.R., Zoller, M.J., Karas, J.L., Dalgarno, D.C.

(1995) Structure 3: 1061-1073

Released	1996-11-08
Method	SOLUTION NMR
Chain ID	B
Organism	Homo sapiens
Macromolecule	ACETYL-THR-PTR-GLU-THR-LEU-NH2

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1D4W: Entity 2	Download File View File

CRYSTAL STRUCTURE OF THE XLP PROTEIN SAP IN COMPLEX WITH SLAM PHOSPHOPEPTIDE

Poy, F., Yaffe, M.B., Sayos, J., Saxena, K., Eck, M.J.

(1999) Mol Cell 4: 555-561

Released	1999-10-14
Method	X-RAY DIFFRACTION 1.8 Å
Chain IDs	C, D
Organism	Homo sapiens
Macromolecule	SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE

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1EEN: Entity 2	Download File View File

CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH ACETYL-D-A-D-BPA-PTYR-L-I-P-Q-Q-G

Puius, Y.A., Zhao, Y., Almo, S.C., Zhang, Z.Y.

(2000) Biochemistry 39: 8171-8179

Released	2001-02-01
Method	X-RAY DIFFRACTION 1.9 Å
Chain ID	B
Macromolecule	ALA-ASP-PBF-PTR-LEU-ILE-PRO

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1EEO: Entity 2	Download File View File

CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH ACETYL-E-L-E-F-PTYR-M-D-Y-E-NH2

Sarmiento, M., Puius, Y.A., Vetter, S.W., Lawrence, D.S., Almo, S.C., Zhang, Z.Y.

(2000) Biochemistry 39: 8171-8179

Released	2001-02-01
Method	X-RAY DIFFRACTION 1.8 Å
Chain ID	B
Macromolecule	ACETYL-E-L-E-F-PTYR-M-D-Y-E-NH2 PEPTIDE

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1F1W: Entity 2	Download File View File

SRC SH2 THREF1TRP MUTANT COMPLEXED WITH THE PHOSPHOPEPTIDE S(PTR)VNVQN

Kimber, M.S., Nachman, J., Cunningham, A.M., Gish, G.D., Pawson, T., Pai, E.F.

(2000) Mol Cell 5: 1043-1049

Released	2000-07-06
Method	X-RAY DIFFRACTION 2.1 Å
Chain ID	B
Macromolecule	S(PTR)VNVQN PHOSPHOPEPTIDE

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1FBV: Entity 2	Download File View File

STRUCTURE OF A CBL-UBCH7 COMPLEX: RING DOMAIN FUNCTION IN UBIQUITIN-PROTEIN LIGASES

Zheng, N., Wang, P., Jeffrey, P.D., Pavletich, N.P.

(2000) Cell 102: 533-539

Released	2000-08-30
Method	X-RAY DIFFRACTION 2.9 Å
Chain ID	B
Organism	Homo sapiens
Macromolecule	ZAP-70 PEPTIDE

1 to 25 of 886 Polymer Entities

Page 1 of 36

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification