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234,136 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Citation Author = "Palzkill, T."

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Search Summary

This query matches 104 Structures.

Refinements

Structure Determination Methodology

experimental (104)

Scientific Name of Source Organism

	Escherichia coli (36)
	Klebsiella pneumoniae (25)
	Norovirus (10)
	Enterobacter cloacae (6)
	Klebsiella pneumoniae subsp. pneumoniae HS11286 (6)
	Norovirus Hu/1968/US (5)
	Severe acute respiratory syndrome coronavirus 2 (5)
	synthetic construct (4)
	Homo sapiens (3)
	Streptomyces clavuligerus (3)

More...

Taxonomy

	Bacteria (79)
	Riboviria (22)
	other sequences (4)
	Eukaryota (3)

Experimental Method

X-RAY DIFFRACTION (104)

Polymer Entity Type

	Protein (104)
	RNA (1)

Refinement Resolution (Å)

	1.0 - 1.5 (21)
	1.5 - 2.0 (38)
	2.0 - 2.5 (30)
	2.5 - 3.0 (14)
	3.0 - 3.5 (1)

Release Date

	2005 - 2009 (4)
	2010 - 2014 (20)
	2015 - 2019 (22)
	2020 - 2024 (49)
	2025 - 2029 (9)

Enzyme Classification Name

	Hydrolases (87)
	Transferases (6)

Symmetry Type

	Asymmetric (74)
	Cyclic (31)
	Dihedral (1)

SCOP Classification

	Multi-domain proteins (alpha and beta) (48)
	All beta proteins (6)
	Artifacts (6)
	Alpha and beta proteins (a+b) (5)

AllSelected

1 to 25 of 104 Structures

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3C7U \| pdb_00003c7u	Download File View File

Structural Insight into the Kinetics and Cp of interactions between TEM-1-Lactamase and BLIP

Wang, J., Chow, D.-C.

(2009) J Biological Chem 284: 595-609

Released	2008-10-07
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Escherichia coli Streptomyces clavuligerus
Macromolecule	Beta-lactamase (protein) Beta-lactamase inhibitory protein (protein)

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3C7V \| pdb_00003c7v	Download File View File

Structural Insight into the Kinetics and Delta-Cp of interactions between TEM-1 Beta-Lactamase and BLIP

Wang, J., Chow, D.-C.

(2009) J Biological Chem 284: 595-609

Released	2008-10-07
Method	X-RAY DIFFRACTION 2.07 Å
Organisms	Escherichia coli Streptomyces clavuligerus
Macromolecule	Beta-lactamase (protein) Beta-lactamase inhibitory protein (protein)

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3CMZ \| pdb_00003cmz	Download File View File

TEM-1 Class-A beta-lactamase L201P mutant apo structure

Marciano, D.C., Wang, X., Wang, J., Chen, Y., Thomas, V.L., Shoichet, B.K., Palzkill, T.

(2008) J Mol Biology 384: 151-164

Released	2008-11-25
Method	X-RAY DIFFRACTION 1.92 Å
Organisms	Escherichia coli
Macromolecule	Beta-lactamase TEM (protein)
Unique Ligands	PO4

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3JYI \| pdb_00003jyi	Download File View File

Structural and biochemical evidence that a TEM-1 {beta}-lactamase Asn170Gly active site mutant acts via substrate-assisted catalysis

Brown, N.G., Palzkill, T.G., Prasad, B.V.V., Shanker, S.

(2009) J Biological Chem 284: 33703-33712

Released	2009-10-06
Method	X-RAY DIFFRACTION 2.703 Å
Organisms	Escherichia coli
Macromolecule	Beta-lactamase TEM (protein)
Unique Ligands	EPE, PO4

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3OCP \| pdb_00003ocp	Download File View File

Crystal structure of cAMP bound cGMP-dependent protein kinase(92-227)

Kim, J.J., Huang, G., Kwon, T.K., Zwart, P., Headd, J., Kim, C.

(2011) PLoS One 6: e18413-e18413

Released	2011-05-11
Method	X-RAY DIFFRACTION 2.49 Å
Organisms	Homo sapiens
Macromolecule	PRKG1 protein (protein)
Unique Ligands	CMP

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3OD0 \| pdb_00003od0	Download File View File

Crystal structure of cGMP bound cGMP-dependent protein kinase(92-227)

Kim, J.J., Huang, G., Kwon, T.K., Zwart, P., Headd, J., Kim, C.

(2011) PLoS One 6: e18413-e18413

Released	2011-05-11
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Homo sapiens
Macromolecule	PRKG1 protein (protein)
Unique Ligands	PCG

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3OGJ \| pdb_00003ogj	Download File View File

Crystal structure of partial apo (92-227) of cGMP-dependent protein kinase

Kim, J.J., Huang, G., Kwon, T.K., Zwart, P., Headd, J., Kim, C.

(2011) PLoS One 6: e18413-e18413

Released	2011-05-11
Method	X-RAY DIFFRACTION 2.751 Å
Organisms	Homo sapiens
Macromolecule	PRKG1 protein (protein)
Unique Ligands	CMP, PO4

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3QHY \| pdb_00003qhy	Download File View File

Structural, thermodynamic and kinetic analysis of the picomolar binding affinity interaction of the beta-lactamase inhibitor protein-II (BLIP-II) with class A beta-lactamases

Brown, N.G., Chow, D.C., Sankaran, B., Zwart, P., Prasad, B.V.V., Palzkill, T., Berkeley Structural Genomics Center (BSGC)

(2011) J Biological Chem 286: 32723-32735

Released	2011-07-20
Method	X-RAY DIFFRACTION 2.06 Å
Organisms	Bacillus anthracis Streptomyces exfoliatus
Macromolecule	Beta-lactamase (protein) Beta-lactamase inhibitory protein II (protein)

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3QI0 \| pdb_00003qi0	Download File View File

Structural, thermodynamic and kinetic analysis of the picomolar binding affinity interaction of the beta-lactamase inhibitor protein-II (BLIP-II) with class A beta-lactamases

Brown, N.G., Chow, D.C., Sankaran, B., Zwart, P., Prasad, B.V.V., Palzkill, T.

(2011) J Biological Chem 286: 32723-32735

Released	2011-07-20
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Streptomyces exfoliatus
Macromolecule	Beta-lactamase inhibitory protein II (protein)
Unique Ligands	SO4

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4F6H \| pdb_00004f6h	Download File View File

Mutagenesis of zinc ligand residue Cys221 reveals plasticity in the IMP-1 metallo-b-lactamase active site

Horton, L.B., Shanker, S., Sankaran, B., Mikulski, R., Brown, N.G., Phillips, K., Lykissa, E., Prasad, B.V.V., Palzkill, T.G.

(2012) Antimicrob Agents Chemother 56: 5667-5677

Released	2013-03-27
Method	X-RAY DIFFRACTION 1.744 Å
Organisms	Pseudomonas aeruginosa
Macromolecule	Beta-lactamase (protein)
Unique Ligands	PO4, SO4, ZN

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4F6Z \| pdb_00004f6z	Download File View File

Mutagenesis of zinc ligand residue Cys221 reveals plasticity in the IMP-1 metallo-b-lactamase active site

Horton, L.B., Shanker, S., Sankaran, B., Mikulski, R., Brown, N.G., Phillips, K., Lykissa, E., Prasad, B.V.V., Palzkill, T.G.

(2012) Antimicrob Agents Chemother 56: 5667-5677

Released	2013-03-27
Method	X-RAY DIFFRACTION 2 Å
Organisms	Pseudomonas aeruginosa
Macromolecule	Beta-lactamase (protein)
Unique Ligands	FLC, ZN

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4G0A \| pdb_00004g0a	Download File View File

Crystallographic Analysis of Rotavirus NSP2-RNA Complex Reveals Specific Recognition of 5'-GG Sequence for RTPase activity

Hu, L., Prasad, B.V.V.

(2012) J Virol 86: 10547-10557

Released	2012-08-22
Method	X-RAY DIFFRACTION 2.0995 Å
Organisms	Simian 11 rotavirus (serotype 3 / strain SA11-Ramig) synthetic construct
Macromolecule	Non-structural protein 2 (protein) RNA (5'-R(PGPGP*U)-3') (nucleic acid)
Unique Ligands	CL, NA

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4G0J \| pdb_00004g0j	Download File View File

Crystallographic Analysis of Rotavirus NSP2-RNA Complex Reveals Specific Recognition of 5'-GG Sequence for RTPase activity

Hu, L., Prasad, B.V.V.

(2012) J Virol 86: 10547-10557

Released	2012-08-22
Method	X-RAY DIFFRACTION 3.398 Å
Organisms	Simian 11 rotavirus (serotype 3 / strain SA11-Ramig)
Macromolecule	Non-structural protein 2 (protein)

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4IMQ \| pdb_00004imq	Download File View File

Structural Basis of Substrate Specificity and Protease Inhibition in Norwalk Virus

Prasad, B.V.V., Muhaxhiri, Z., Deng, L., Shanker, S., Sankaran, B., Estes, M.K., Palzkill, T., Song, Y.

(2013) J Virol 87: 4281-4292

Released	2013-02-20
Method	X-RAY DIFFRACTION 1.5 Å
Organisms	Norovirus Hu/1968/US synthetic construct
Macromolecule	3C-like protease (protein) PEPTIDE INHIBITOR, syc8 (protein)
Unique Ligands	NA, SCN

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4IMZ \| pdb_00004imz	Download File View File

Structural Basis of Substrate Specificity and Protease Inhibition in Norwalk Virus

Prasad, B.V.V., Muhaxhiri, Z., Deng, L., Shanker, S., Sankaran, B., Estes, M.K., Palzkill, T., Song, Y.

(2013) J Virol 87: 4281-4292

Released	2013-02-20
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Norovirus Hu/1968/US synthetic construct
Macromolecule	Genome polyprotein (protein) peptide inhibitor, syc 10 (protein)
Unique Ligands	NA, SCN

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4IN1 \| pdb_00004in1	Download File View File

Structural Basis of Substrate Specificity and Protease Inhibition in Norwalk Virus

Prasad, B.V.V., Muhaxhiri, Z., Deng, L., Shanker, S., Sankaran, B., Estes, M.K., Palzkill, T., Song, Y.

(2013) J Virol 87: 4281-4292

Released	2013-02-20
Method	X-RAY DIFFRACTION 2.05 Å
Organisms	Norovirus Hu/1968/US
Macromolecule	3C-like protease (protein)
Unique Ligands	SO4

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4IN2 \| pdb_00004in2	Download File View File

Structural Basis of Substrate Specificity and Protease Inhibition in Norwalk Virus

Prasad, B.V.V., Muhaxhiri, Z., Deng, L., Shanker, S., Sankaran, B., Estes, M.K., Palzkill, T., Song, Y.

(2013) J Virol 87: 4281-4292

Released	2013-02-20
Method	X-RAY DIFFRACTION 2.401 Å
Organisms	Norovirus Hu/1968/US
Macromolecule	C-like protease (protein)

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4INH \| pdb_00004inh	Download File View File

Structural Basis of Substrate Specificity and Protease Inhibition in Norwalk Virus

Prasad, B.V.V., Muhaxhiri, Z., Deng, L., Shanker, S., Sankaran, B., Estes, M.K., Palzkill, T., Song, Y.

(2013) J Virol 87: 4281-4292

Released	2013-02-20
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Norovirus Hu/1968/US synthetic construct
Macromolecule	Genome polyprotein (protein) peptide inhibitor, syc59 (protein)
Unique Ligands	DMS

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4PM5 \| pdb_00004pm5	Download File View File

Crystal structure of CTX-M-14 S70G beta-lactamase in complex with cefotaxime at 1.26 Angstroms resolution

Adamski, C.J., Cardenas, A.M., Sankaran, B., Palzkill, T.

(2015) Biochemistry 54: 447-457

Released	2014-12-31
Method	X-RAY DIFFRACTION 1.261 Å
Organisms	Klebsiella pneumoniae subsp. pneumoniae HS11286
Macromolecule	Beta-lactamase CTX-M-14 (protein)
Unique Ligands	CE3, SO4

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4PM6 \| pdb_00004pm6	Download File View File

Crystal structure of CTX-M-14 S70G beta-lactamase at 1.56 Angstroms resolution

Adamski, C.J., Cardenas, A.M., Sankaran, B., Palzkill, T.

(2015) Biochemistry 54: 447-457

Released	2014-12-31
Method	X-RAY DIFFRACTION 1.56 Å
Organisms	Klebsiella pneumoniae subsp. pneumoniae HS11286
Macromolecule	Beta-lactamase CTX-M-14 (protein)
Unique Ligands	SO4

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4PM7 \| pdb_00004pm7	Download File View File

Crystal structure of CTX-M-14 S70G:S237A in complex with cefotaxime at 1.29 Angstroms resolution

Adamski, C.J., Cardenas, A.M., Sankaran, B., Palzkill, T.

(2015) Biochemistry 54: 447-457

Released	2014-12-31
Method	X-RAY DIFFRACTION 1.29 Å
Organisms	Klebsiella pneumoniae subsp. pneumoniae HS11286
Macromolecule	Beta-lactamase CTX-M-14 (protein)
Unique Ligands	CE3

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4PM8 \| pdb_00004pm8	Download File View File

Crystal structure of CTX-M-14 S70G:S237A beta-lactamase at 1.17 Angstroms resolution

Adamski, C.J., Cardenas, A.M., Sankaran, B., Palzkill, T.

(2015) Biochemistry 54: 447-457

Released	2014-12-31
Method	X-RAY DIFFRACTION 1.169 Å
Organisms	Klebsiella pneumoniae subsp. pneumoniae HS11286
Macromolecule	Beta-lactamase CTX-M-14 (protein)
Unique Ligands	SO4

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4PM9 \| pdb_00004pm9	Download File View File

Crystal structure of CTX-M-14 S70G:S237A:R276A beta-lactamase in complex with cefotaxime at 1.45 Angstroms resolution

Cardenas, A.M., Adamski, C.J., Sankaran, B., Brown, N.G., Horton, L.B., Palzkill, T.

(2015) Biochemistry 54: 447-457

Released	2014-12-31
Method	X-RAY DIFFRACTION 1.454 Å
Organisms	Klebsiella pneumoniae subsp. pneumoniae HS11286
Macromolecule	Beta-lactamase CTX-M-14 (protein)
Unique Ligands	CE3

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4PMA \| pdb_00004pma	Download File View File

Crystal structure of CTX-M-14 S70G:S237A:R276A beta-lactamase at 1.39 Angstroms resolution

Cardenas, A.M., Adamski, C.J., Brown, N.G., Horton, L.B., Sankaran, B., Palzkill, T.

(2015) Biochemistry 54: 447-457

Released	2014-12-31
Method	X-RAY DIFFRACTION 1.399 Å
Organisms	Klebsiella pneumoniae subsp. pneumoniae HS11286
Macromolecule	Beta-lactamase CTX-M-14 (protein)
Unique Ligands	SO4