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232,059 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Citation Author = "Hsieh, J.Y."

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Search Summary

This query matches 21 Structures.

Refinements

Structure Determination Methodology

experimental (21)

Scientific Name of Source Organism

	Tetronarce californica (19)
	Electrophorus electricus (1)
	Gallus gallus (1)

Taxonomy

Eukaryota (21)

Experimental Method

X-RAY DIFFRACTION (21)

Polymer Entity Type

Protein (21)

Refinement Resolution (Å)

	1.0 - 1.5 (1)
	2.0 - 2.5 (10)
	2.5 - 3.0 (8)
	3.0 - 3.5 (1)
	> 4.5 (1)

Release Date

	1995 - 1999 (8)
	2000 - 2004 (12)
	2005 - 2009 (1)

Enzyme Classification Name

Hydrolases (21)

Symmetry Type

	Cyclic (18)
	Asymmetric (3)

SCOP Classification

	Alpha and beta proteins (a/b) (20)
	Alpha and beta proteins (a+b) (1)

AllSelected

1 to 21 of 21 Structures

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1AX9	Download File View File

ACETYLCHOLINESTERASE COMPLEXED WITH EDROPHONIUM, LAUE DATA

Raves, M.L., Ravelli, R.B.G., Sussman, J.L., Harel, M., Silman, I.

(1998) Acta Crystallogr D Biol Crystallogr 54: 1359-1366

Released	1998-02-11
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Tetronarce californica
Macromolecule	ACETYLCHOLINESTERASE (protein)
Unique Ligands	EDR

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1CFJ	Download File View File

METHYLPHOSPHONYLATED ACETYLCHOLINESTERASE (AGED) OBTAINED BY REACTION WITH O-ISOPROPYLMETHYLPHOSPHONOFLUORIDATE (GB, SARIN)

Millard, C.B., Silman, I., Sussman, J.L.

(1999) Biochemistry 38: 7032-7039

Released	1999-06-25
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Tetronarce californica
Macromolecule	PROTEIN (ACETYLCHOLINESTERASE) (protein)
Unique Ligands	GB, NAG

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1EEA	Download File View File

Acetylcholinesterase

Raves, M.L., Giles, K., Schrag, J.D., Schmid, M.F., Phillips Jr., G.N., Wah, C., Howard, A.J., Silman, I., Sussman, J.L.

(1998) Structure And Function Of Cholinesterases And Related Proteins

Released	1999-02-01
Method	X-RAY DIFFRACTION 4.5 Å
Organisms	Electrophorus electricus
Macromolecule	PROTEIN (ACETYLCHOLINESTERASE) (protein)

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1H22	Download File View File

Structure of acetylcholinesterase (E.C. 3.1.1.7) complexed with (S,S)-(-)-bis(10)-hupyridone at 2.15A resolution

Wong, D.M., Greenblatt, H.M., Carlier, P.R., Han, Y.-F., Pang, Y.-P., Silman, I., Sussman, J.L.

(2003) J Am Chem Soc 125: 363

Released	2002-12-23
Method	X-RAY DIFFRACTION 2.15 Å
Organisms	Tetronarce californica
Macromolecule	ACETYLCHOLINESTERASE (protein)
Unique Ligands	E10, NAG

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1H23	Download File View File

Structure of acetylcholinesterase (E.C. 3.1.1.7) complexed with (S,S)-(-)-bis(12)-hupyridone at 2.15A resolution

Wong, D.M., Greenblatt, H.M., Carlier, P.R., Han, Y.F., Pang, Y.P., Silman, I., Sussman, J.L.

(2003) J Am Chem Soc 125: 363

Released	2002-12-23
Method	X-RAY DIFFRACTION 2.15 Å
Organisms	Tetronarce californica
Macromolecule	ACETYLCHOLINESTERASE (protein)
Unique Ligands	E12, NAG

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1QID	Download File View File

SPECIFIC CHEMICAL AND STRUCTURAL DAMAGE AT NINE TIME POINTS (POINT A) CAUSED BY INTENSE SYNCHROTRON RADIATION TO TORPEDO CALIFORNICA ACETYLCHOLINESTERASE

Kryger, G., Weik, M., Ravelli, R.B.G.

(2000) Proc Natl Acad Sci U S A 97: 623-628

Released	2000-01-28
Method	X-RAY DIFFRACTION 2.05 Å
Organisms	Tetronarce californica
Macromolecule	ACETYLCHOLINESTERASE (protein)

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1QIE	Download File View File

SPECIFIC CHEMICAL AND STRUCTURAL DAMAGE AT NINE TIME POINTS (POINT B) CAUSED BY INTENSE SYNCHROTRON RADIATION TO TORPEDO CALIFORNICA ACETYLCHOLINESTERASE

Kryger, G., Weik, M., Ravelli, R.B.G.

(2000) Proc Natl Acad Sci U S A 97: 623-628

Released	2000-01-28
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Tetronarce californica
Macromolecule	ACETYLCHOLINESTERASE (protein)

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1QIF	Download File View File

SPECIFIC CHEMICAL AND STRUCTURAL DAMAGE AT NINE TIME POINTS (POINT C) CAUSED BY INTENSE SYNCHROTRON RADIATION TO TORPEDO CALIFORNICA ACETYLCHOLINESTERASE

Kryger, G., Weik, M., Ravelli, R.B.G.

(2000) Proc Natl Acad Sci U S A 97: 623-628

Released	2000-01-28
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Tetronarce californica
Macromolecule	ACETYLCHOLINESTERASE (protein)

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1QIG	Download File View File

SPECIFIC CHEMICAL AND STRUCTURAL DAMAGE AT NINE TIME POINTS (POINT D) CAUSED BY INTENSE SYNCHROTRON RADIATION TO TORPEDO CALIFORNICA ACETYLCHOLINESTERASE

Kryger, G., Weik, M., Ravelli, R.B.G.

(2000) Proc Natl Acad Sci U S A 97: 623-628

Released	2000-01-28
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Tetronarce californica
Macromolecule	ACETYLCHOLINESTERASE (protein)

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1QIH	Download File View File

SPECIFIC CHEMICAL AND STRUCTURAL DAMAGE AT NINE TIME POINTS (POINT E) CAUSED BY INTENSE SYNCHROTRON RADIATION TO TORPEDO CALIFORNICA ACETYLCHOLINESTERASE

Kryger, G., Weik, M., Ravelli, R.B.G.

(2000) Proc Natl Acad Sci U S A 97: 623-628

Released	2000-01-28
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Tetronarce californica
Macromolecule	PROTEIN (ACETYLCHOLINESTERASE) (protein)

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1QII	Download File View File

SPECIFIC CHEMICAL AND STRUCTURAL DAMAGE AT NINE TIME POINTS (POINT F) CAUSED BY INTENSE SYNCHROTRON RADIATION TO TORPEDO CALIFORNICA ACETYLCHOLINESTERASE

Kryger, G., Weik, M., Ravelli, R.B.G.

(2000) Proc Natl Acad Sci U S A 97: 623-628

Released	2000-01-28
Method	X-RAY DIFFRACTION 2.65 Å
Organisms	Tetronarce californica
Macromolecule	ACETYLCHOLINESTERASE (protein)

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1QIJ	Download File View File

SPECIFIC CHEMICAL AND STRUCTURAL DAMAGE AT NINE TIME POINTS (POINT G) CAUSED BY INTENSE SYNCHROTRON RADIATION TO TORPEDO CALIFORNICA ACETYLCHOLINESTERASE

Kryger, G., Weik, M., Ravelli, R.B.G.

(2000) Proc Natl Acad Sci U S A 97: 623-628

Released	2000-01-28
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Tetronarce californica
Macromolecule	ACETYLCHOLINESTERASE (protein)

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1QIK	Download File View File

SPECIFIC CHEMICAL AND STRUCTURAL DAMAGE AT NINE TIME POINTS (POINT H) CAUSED BY INTENSE SYNCHROTRON RADIATION TO TORPEDO CALIFORNICA ACETYLCHOLINESTERASE

Kryger, G., Weik, M., Ravelli, R.B.G.

(2000) Proc Natl Acad Sci U S A 97: 623-628

Released	2000-01-28
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Tetronarce californica
Macromolecule	ACETYLCHOLINESTERASE (protein)

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1QIM	Download File View File

SPECIFIC CHEMICAL AND STRUCTURAL DAMAGE AT NINE TIME POINTS (POINT I) CAUSED BY INTENSE SYNCHROTRON RADIATION TO TORPEDO CALIFORNICA ACETYLCHOLINESTERASE

Kryger, G., Weik, M., Ravelli, R.B.G.

(2000) Proc Natl Acad Sci U S A 97: 623-628

Released	2000-01-28
Method	X-RAY DIFFRACTION 3 Å
Organisms	Tetronarce californica
Macromolecule	ACETYLCHOLINESTERASE (protein)

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1QIO	Download File View File

SPECIFIC CHEMICAL AND STRUCTURAL DAMAGE CAUSED BY INTENSE SYNCHROTRON RADIATION TO HEN EGG WHITE LYSOZYME

Kryger, G., Weik, M., Ravelli, R.B.

(2000) Proc Natl Acad Sci U S A 97: 623-628

Released	2001-04-11
Method	X-RAY DIFFRACTION 1.2 Å
Organisms	Gallus gallus
Macromolecule	LYSOZYME (protein)
Unique Ligands	CL, NA

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1SOM	Download File View File

TORPEDO CALIFORNICA ACETYLCHOLINESTERASE INHIBITED BY NERVE AGENT GD (SOMAN).

Greenblatt, H.M., Millard, C.B., Sussman, J.L., Silman, I.

(1999) Biochemistry 38: 7032-7039

Released	1999-06-25
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Tetronarce californica
Macromolecule	PROTEIN (ACETYLCHOLINESTERASE) (protein)
Unique Ligands	NAG, UNX, VXA

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1VOT	Download File View File

ACETYLCHOLINESTERASE (E.C. 3.1.1.7) COMPLEXED WITH HUPERZINE A

Raves, M.L., Harel, M., Silman, I., Sussman, J.L.

(1997) Nat Struct Biol 4: 57-63

Released	1997-06-16
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Tetronarce californica
Macromolecule	ACETYLCHOLINESTERASE (protein)
Unique Ligands	HUP

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1ZGB	Download File View File

Crystal Structure of Torpedo Californica Acetylcholinesterase in Complex With an (R)-Tacrine(10)-Hupyridone Inhibitor.

Haviv, H., Wong, D.M., Greenblatt, H.M., Carlier, P.R., Pang, Y.P., Silman, I., Sussman, J.L., Israel Structural Proteomics Center (ISPC)

(2005) J Am Chem Soc 127: 11029-11036

Released	2005-08-16
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Tetronarce californica
Macromolecule	Acetylcholinesterase (protein)
Unique Ligands	A1E, NAG

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2ACE	Download File View File

NATIVE ACETYLCHOLINESTERASE (E.C. 3.1.1.7) FROM TORPEDO CALIFORNICA

Harel, M., Raves, M.L., Silman, I., Sussman, J.L.

(1997) Nat Struct Biol 4: 57-63

Released	1996-11-08
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Tetronarce californica
Macromolecule	ACETYLCHOLINESTERASE (protein)
Unique Ligands	ACH

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2ACK	Download File View File

ACETYLCHOLINESTERASE COMPLEXED WITH EDROPHONIUM, MONOCHROMATIC DATA

Raves, M.L., Sussman, J.L., Harel, M., Silman, I.

(1998) Acta Crystallogr D Biol Crystallogr 54: 1359-1366

Released	1998-02-11
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Tetronarce californica
Macromolecule	ACETYLCHOLINESTERASE (protein)
Unique Ligands	EDR

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2DFP	Download File View File

X-RAY STRUCTURE OF AGED DI-ISOPROPYL-PHOSPHORO-FLUORIDATE (DFP) BOUND TO ACETYLCHOLINESTERASE

Kryger, G., Millard, C.B., Silman, I., Sussman, J.L.

(1999) Biochemistry 38: 7032-7039

Released	1999-06-28
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Tetronarce californica
Macromolecule	PROTEIN (ACETYLCHOLINESTERASE) (protein)
Unique Ligands	MES, NAG
Unique branched monosaccharides	NAG