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234,440 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Citation Author = "Hirao, M."

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Search Summary

This query matches 83 Structures.

Refinements

Structure Determination Methodology

experimental (83)

Scientific Name of Source Organism

	Homo sapiens (65)
	Mus musculus (22)

Taxonomy

	Eukaryota (83)
	Eukaryota (eukaryotes) (1)

Experimental Method

	X-RAY DIFFRACTION (80)
	SOLUTION NMR (2)
	ELECTRON MICROSCOPY (1)

Polymer Entity Type

Protein (83)

Refinement Resolution (Å)

	1.0 - 1.5 (2)
	1.5 - 2.0 (15)
	2.0 - 2.5 (21)
	2.5 - 3.0 (30)
	3.0 - 3.5 (12)
	3.5 - 4.0 (1)

Release Date

	1995 - 1999 (1)
	2000 - 2004 (12)
	2005 - 2009 (17)
	2010 - 2014 (29)
	2015 - 2019 (19)
	2020 - 2024 (5)

Enzyme Classification Name

	Transferases (32)
	Hydrolases (7)
	Ligases (3)

Membrane Protein Annotation

OPM (1)

Symmetry Type

	Asymmetric (62)
	Cyclic (31)

SCOP Classification

	All beta proteins (27)
	Alpha and beta proteins (a+b) (25)
	Small proteins (16)
	Artifacts (16)
	All alpha proteins (4)
	Membrane and cell surface proteins and peptides (4)

AllSelected

1 to 25 of 83 Structures

Page 1 of 4

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1D0G \| pdb_00001d0g	Download File View File

CRYSTAL STRUCTURE OF DEATH RECEPTOR 5 (DR5) BOUND TO APO2L/TRAIL

Hymowitz, S.G., Christinger, H.W., Fuh, G., O'Connell, M.P., Kelley, R.F., Ashkenazi, A., de Vos, A.M.

(1999) Mol Cell 4: 563-571

Released	1999-10-22
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Homo sapiens
Macromolecule	APOPTOSIS-2 LIGAND (protein) DEATH RECEPTOR-5 (protein)
Unique Ligands	CL, ZN

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1DG6 \| pdb_00001dg6	Download File View File

CRYSTAL STRUCTURE OF APO2L/TRAIL

Hymowitz, S.G., O'ConnelL, M.P., Ultsch, M.H., de Vos, A.M., Kelley, R.F.

(2000) Biochemistry 39: 633-650

Released	2000-01-26
Method	X-RAY DIFFRACTION 1.3 Å
Organisms	Homo sapiens
Macromolecule	APO2L/TNF-RELATED APOPOTIS INDUCING LIGAND (TRAIL) (protein)
Unique Ligands	CL, ZN

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1JPY \| pdb_00001jpy	Download File View File

Crystal structure of IL-17F

Hymowitz, S.G., Filvaroff, E.H., Yin, J., Lee, J., Cai, L., Risser, P., Maruoka, M., Mao, W., Foster, J., Kelley, R., Pan, G., Gurney, A.L., de Vos, A.M., Starovasnik, M.A.

(2001) EMBO J 20: 5332-5341

Released	2001-09-28
Method	X-RAY DIFFRACTION 2.85 Å
Organisms	Homo sapiens
Macromolecule	interleukin 17F (protein)
Unique Ligands	NAG, SO4
Unique branched monosaccharides	NAG, NDG

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1OSG \| pdb_00001osg	Download File View File

Complex between BAFF and a BR3 derived peptide presented in a beta-hairpin scaffold

Gordon, N.C., Pan, B., Hymowitz, S.G., Yin, J.P., Kelley, R.F., Cochran, A.G., Yan, M., Dixit, V.M., Fairbrother, W.J., Starovasnik, M.A.

(2003) Biochemistry 42: 5977-5983

Released	2003-05-27
Method	X-RAY DIFFRACTION 3 Å
Organisms	Homo sapiens
Macromolecule	BR3 derived PEPTIDE (protein) Tumor necrosis factor ligand superfamily member 13B (protein)
Unique Ligands	MG

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1OSX \| pdb_00001osx	Download File View File

Solution Structure of the Extracellular Domain of BLyS Receptor 3 (BR3)

Gordon, N.C., Pan, B., Hymowitz, S.G., Yin, J.P., Kelley, R.F., Cochran, A.G., Yan, M., Dixit, V.M., Fairbrother, W.J., Starovasnik, M.A.

(2003) Biochemistry 42: 5977-5983

Released	2003-05-27
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	Tumor necrosis factor receptor superfamily member 13C (protein)

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1RJ7 \| pdb_00001rj7	Download File View File

Crystal structure of EDA-A1

Hymowitz, S.G., Compaan, D.M., Yan, M., Ackerly, H., Dixit, V.M., Starovasnik, M.A., de Vos, A.M.

(2003) Structure 11: 1513-1520

Released	2003-12-09
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Homo sapiens
Macromolecule	Ectodysplasin A (protein)

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1RJ8 \| pdb_00001rj8	Download File View File

The crystal structure of TNF family member EDA-A2

Hymowitz, S.G., Compaan, D.M., Yan, M., Ackerly, H., Dixit, V.M., Starovasnik, M.A., de Vos, A.M.

(2003) Structure 11: 1513-1520

Released	2003-12-09
Method	X-RAY DIFFRACTION 2.23 Å
Organisms	Homo sapiens
Macromolecule	ectodysplasin-A isoform EDA-A2 (protein)

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1U5X \| pdb_00001u5x	Download File View File

Crystal structure of murine APRIL at pH 5.0

Wallweber, H.J., Compaan, D.M., Starovasnik, M.A., Hymowitz, S.G.

(2004) J Mol Biology 343: 283-290

Released	2004-10-12
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Mus musculus
Macromolecule	Tumor necrosis factor ligand superfamily member 13 (protein)

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1U5Y \| pdb_00001u5y	Download File View File

Crystal structure of murine APRIL, pH 8.0

Wallweber, H.J., Compaan, D.M., Starovasnik, M.A., Hymowitz, S.G.

(2004) J Mol Biology 343: 283-290

Released	2004-10-12
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Mus musculus
Macromolecule	Tumor necrosis factor ligand superfamily member 13 (protein)

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1U5Z \| pdb_00001u5z	Download File View File

The Crystal structure of murine APRIL, pH 8.5

Wallweber, H.J., Compaan, D.M., Starovasnik, M.A., Hymowitz, S.G.

(2004) J Mol Biology 343: 283-290

Released	2004-10-12
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Mus musculus
Macromolecule	Tumor necrosis factor ligand superfamily member 13 (protein)
Unique Ligands	NI

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1XU1 \| pdb_00001xu1	Download File View File

The crystal structure of APRIL bound to TACI

Hymowitz, S.G., Patel, D.R., Wallweber, H.J.A., Runyon, S., Yan, M., Yin, J., Shriver, S.K., Gordon, N.C., Pan, B., Skelton, N.J., Kelley, R.F., Starovasnik, M.A.

(2005) J Biological Chem 280: 7218-7227

Released	2004-11-09
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens Mus musculus
Macromolecule	Tumor necrosis factor ligand superfamily member 13 (protein) Tumor necrosis factor receptor superfamily member 13B (protein)
Unique Ligands	NI

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1XU2 \| pdb_00001xu2	Download File View File

The crystal structure of APRIL bound to BCMA

Hymowitz, S.G., Patel, D.R., Wallweber, H.J.A., Runyon, S., Yan, M., Yin, J., Shriver, S.K., Gordon, N.C., Pan, B., Skelton, N.J., Kelley, R.F., Starovasnik, M.A.

(2005) J Biological Chem 280: 7218-7227

Released	2004-11-09
Method	X-RAY DIFFRACTION 2.35 Å
Organisms	Homo sapiens Mus musculus
Macromolecule	Tumor necrosis factor ligand superfamily member 13 (protein) Tumor necrosis factor receptor superfamily member 17 (protein)
Unique Ligands	NI

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1XUT \| pdb_00001xut	Download File View File

Solution structure of TACI-CRD2

Hymowitz, S.G., Patel, D.R., Wallweber, H.J., Runyon, S., Yan, M., Yin, J., Shriver, S.K., Gordon, N.C., Pan, B., Skelton, N.J., Kelley, R.F., Starovasnik, M.A.

(2005) J Biological Chem 280: 7218-7227

Released	2004-11-09
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	Tumor necrosis factor receptor superfamily member 13B (protein)

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1ZA3 \| pdb_00001za3	Download File View File

The crystal structure of the YSd1 Fab bound to DR5

Fellouse, F.A., Li, B., Compaan, D.M., Peden, A.A., Hymowitz, S.G., Sidhu, S.S.

(2005) J Mol Biology 348: 1153-1162

Released	2005-06-14
Method	X-RAY DIFFRACTION 3.35 Å
Organisms	Homo sapiens
Macromolecule	Fab-YSd1 heavy chain (protein) Fab-YSd1 light chain (protein) Tumor necrosis factor receptor superfamily member 10B (protein)

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2AW2 \| pdb_00002aw2	Download File View File

Crystal structure of the human BTLA-HVEM complex

Compaan, D.M., Gonzalez, L.C., Tom, I., Loyet, K.M., Eaton, D., Hymowitz, S.G.

(2005) J Biological Chem 280: 39553-39561

Released	2005-09-27
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Homo sapiens
Macromolecule	B and T lymphocyte attenuator (protein) Tumor necrosis factor receptor superfamily member 14 (protein)
Unique Ligands	NI
Unique branched monosaccharides	FUL, NAG

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2H9G \| pdb_00002h9g	Download File View File

Crystal structure of phage derived Fab BdF1 with human Death Receptor 5 (DR5)

Hymowitz, S.G., Compaan, D.M.

(2006) J Mol Biology 361: 522-536

Released	2006-08-08
Method	X-RAY DIFFRACTION 2.32 Å
Organisms	Homo sapiens
Macromolecule	Fab BdF1, heavy chain (protein) Fab BdF1, light chain (protein) Tumor necrosis factor receptor superfamily member 10B precursor (protein)

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2HEV \| pdb_00002hev	Download File View File

Crystal structure of the complex between OX40L and OX40

Hymowitz, S.G., Compaan, D.M.

(2006) Structure 14: 1321-1330

Released	2006-08-29
Method	X-RAY DIFFRACTION 2.41 Å
Organisms	Homo sapiens
Macromolecule	Tumor necrosis factor ligand superfamily member 4 (protein) Tumor necrosis factor receptor superfamily member 4 (protein)
Unique Ligands	NAG

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2HEW \| pdb_00002hew	Download File View File

The X-ray crystal structure of murine OX40L

Hymowitz, S.G., Compaan, D.M.

(2006) Structure 14: 1321-1330

Released	2006-08-29
Method	X-RAY DIFFRACTION 1.45 Å
Organisms	Mus musculus
Macromolecule	Tumor necrosis factor ligand superfamily member 4 (protein)
Unique Ligands	NAG, SO4

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2HEY \| pdb_00002hey	Download File View File

Crystal structure of murine OX40L bound to human OX40

Hymowitz, S.G.

(2006) Structure 14: 1321-1330

Released	2006-08-29
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens Mus musculus
Macromolecule	Tumor necrosis factor ligand superfamily member 4 (protein) Tumor necrosis factor receptor superfamily member 4 (protein)
Unique Ligands	SO4

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2HFF \| pdb_00002hff	Download File View File

Crystal structure of CB2 Fab

Hymowitz, S.G.

(2006) Blood 108: 3103-3111

Released	2006-11-07
Method	X-RAY DIFFRACTION 1.95 Å
Organisms	Homo sapiens
Macromolecule	CB2 Fab, heavy chain (protein) CB2 Fab, light chain (protein)

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2HFG \| pdb_00002hfg	Download File View File

Crystal structure of hBR3 bound to CB3s-Fab

Hymowitz, S.G.

(2006) Blood 108: 3103-3111

Released	2006-11-07
Method	X-RAY DIFFRACTION 2.61 Å
Organisms	Homo sapiens
Macromolecule	CB3s Fab heavy chain (protein) CB3s Fab light chain (kappa) (protein) Tumor necrosis factor receptor superfamily member 13C (protein)

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2RAW \| pdb_00002raw	Download File View File

Crystal structure of the Borealin-Survivin complex

Hymowitz, S.G.

(2007) J Biological Chem 282: 35018-35023

Released	2007-10-30
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Homo sapiens
Macromolecule	Baculoviral IAP repeat-containing protein 5 (protein) Borealin (protein)
Unique Ligands	ZN

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2RAX \| pdb_00002rax	Download File View File

Crystal structure of Borealin (20-78) bound to Survivin (1-120)

Hymowitz, S.G.

(2007) J Biological Chem 282: 35018-35023

Released	2007-10-30
Method	X-RAY DIFFRACTION 3.3 Å
Organisms	Homo sapiens
Macromolecule	Baculoviral IAP repeat-containing protein 5 (protein) Borealin (protein)
Unique Ligands	ZN

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3DVG \| pdb_00003dvg	Download File View File

Crystal structure of K63-specific fab Apu.3A8 bound to K63-linked di-ubiquitin

Hymowitz, S.G.

(2008) Cell 134: 668-678

Released	2008-09-30
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Homo sapiens
Macromolecule	Human IgG1 fab fragment heavy chain (protein) Human IgG1 fab fragment light chain (protein) Ubiquitin (protein) Ubiquitin D77 (protein)

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3DVN \| pdb_00003dvn	Download File View File

Crystal structure of K63-specific fab Apu2.16 bound to K63-linked di-ubiquitin

Hymowitz, S.G.

(2008) Cell 134: 668-678

Released	2008-09-30
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Homo sapiens
Macromolecule	Human IgG1 fab fragment heavy chain (protein) Human IgG1 fab fragment light chain (protein) Ubiquitin (protein) Ubiquitin D77 (protein)

1 to 25 of 83 Structures

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification

1D0G | pdb_00001d0g

1DG6 | pdb_00001dg6

1JPY | pdb_00001jpy

1OSG | pdb_00001osg

1OSX | pdb_00001osx

1RJ7 | pdb_00001rj7

1RJ8 | pdb_00001rj8

1U5X | pdb_00001u5x

1U5Y | pdb_00001u5y

1U5Z | pdb_00001u5z

1XU1 | pdb_00001xu1

1XU2 | pdb_00001xu2

1XUT | pdb_00001xut

1ZA3 | pdb_00001za3

2AW2 | pdb_00002aw2

2H9G | pdb_00002h9g

2HEV | pdb_00002hev

2HEW | pdb_00002hew

2HEY | pdb_00002hey

2HFF | pdb_00002hff

2HFG | pdb_00002hfg

2RAW | pdb_00002raw

2RAX | pdb_00002rax

3DVG | pdb_00003dvg

3DVN | pdb_00003dvn