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234,440 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Citation Author = "Haire, L.F."

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Search Summary

This query matches 34 Structures.

Refinements

Structure Determination Methodology

experimental (34)

Scientific Name of Source Organism

	Influenza A virus (23)
	Influenza A virus (A/Viet Nam/1203/2004(H5N1)) (3)
	Influenza A virus (A/California/07/2009(H1N1)) (2)
	Influenza A virus (A/Netherlands/2631_1202/2010(H1N1)) (2)
	Influenza A virus (A/Vietnam/1194/2004(H5N1)) (2)
	Influenza A virus (A/Finland/486/2004 (H3N2)) (1)
	Influenza A virus (A/X-31(H3N2)) (1)

Taxonomy

Riboviria (34)

Experimental Method

X-RAY DIFFRACTION (34)

Polymer Entity Type

Protein (34)

Refinement Resolution (Å)

	1.5 - 2.0 (9)
	2.0 - 2.5 (6)
	2.5 - 3.0 (18)
	3.5 - 4.0 (1)

Release Date

	2005 - 2009 (14)
	2010 - 2014 (20)

Enzyme Classification Name

Hydrolases (19)

Symmetry Type

	Cyclic (34)
	Asymmetric (2)

SCOP Classification

	All beta proteins (33)
	Coiled coil proteins (8)

AllSelected

1 to 25 of 34 Structures

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2HT5 \| pdb_00002ht5	Download File View File

N8 Neuraminidase

Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.

(2006) Nature 443: 45-49

Released	2006-09-05
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Influenza A virus
Macromolecule	Neuraminidase (protein)
Unique Ligands	CA, NDG

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2HT7 \| pdb_00002ht7	Download File View File

N8 neuraminidase in open complex with oseltamivir

Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.

(2006) Nature 443: 45-49

Released	2006-09-05
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Influenza A virus
Macromolecule	Neuraminidase (protein)
Unique Ligands	G39

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2HT8 \| pdb_00002ht8	Download File View File

N8 neuraminidase in complex with oseltamivir

Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.

(2006) Nature 443: 45-49

Released	2006-09-05
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Influenza A virus
Macromolecule	Neuraminidase (protein)
Unique Ligands	G39

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2HTQ \| pdb_00002htq	Download File View File

N8 neuraminidase in complex with zanamivir

Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.

(2006) Nature 443: 45-49

Released	2006-09-05
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Influenza A virus
Macromolecule	Neuraminidase (protein)
Unique Ligands	ZMR

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2HTR \| pdb_00002htr	Download File View File

N8 neuraminidase in complex with DANA

Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.

(2006) Nature 443: 45-49

Released	2006-09-05
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Influenza A virus
Macromolecule	Neuraminidase (protein)
Unique Ligands	DAN

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2HTU \| pdb_00002htu	Download File View File

N8 neuraminidase in complex with peramivir

Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.

(2006) Nature 443: 45-49

Released	2006-09-05
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Influenza A virus
Macromolecule	Neuraminidase (protein)
Unique Ligands	BCZ

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2HTV \| pdb_00002htv	Download File View File

N4 neuraminidase

Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.

(2006) Nature 443: 45-49

Released	2006-09-05
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Influenza A virus
Macromolecule	Neuraminidase (protein)
Unique Ligands	CA, NAG

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2HTW \| pdb_00002htw	Download File View File

N4 neuraminidase in complex with DANA

Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.

(2006) Nature 443: 45-49

Released	2006-09-05
Method	X-RAY DIFFRACTION 3.5 Å
Organisms	Influenza A virus
Macromolecule	Neuraminidase (protein)
Unique Ligands	DAN

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2HTY \| pdb_00002hty	Download File View File

N1 neuraminidase

Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.

(2006) Nature 443: 45-49

Released	2006-09-05
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Influenza A virus
Macromolecule	Neuraminidase (protein)
Unique Ligands	CA, NAG, NDG

Explore in 3D

2HU0 \| pdb_00002hu0	Download File View File

N1 neuraminidase in complex with oseltamivir 1

Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.

(2006) Nature 443: 45-49

Released	2006-09-05
Method	X-RAY DIFFRACTION 2.95 Å
Organisms	Influenza A virus
Macromolecule	Neuraminidase (protein)
Unique Ligands	G39

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2HU4 \| pdb_00002hu4	Download File View File

N1 neuraminidase in complex with oseltamivir 2

Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.

(2006) Nature 443: 45-49

Released	2006-09-05
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Influenza A virus
Macromolecule	Neuraminidase (protein)
Unique Ligands	G39

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2YP2 \| pdb_00002yp2	Download File View File

Haemagglutinin of 2004 Human H3N2 Virus

Xiong, X., Lin, Y.P., Wharton, S.A., Martin, S.R., Coombs, P.J., Vachieri, S.G., Christodoulou, E., Walker, P.A., Liu, J., Skehel, J.J., Gamblin, S.J., Hay, A.J., Daniels, R.S., McCauley, J.W.

(2012) Proc Natl Acad Sci U S A 109: 21474

Released	2012-11-07
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Influenza A virus
Macromolecule	HEMAGGLUTININ (protein)
Unique Ligands	EPE, NAG, TAM
Unique branched monosaccharides	MAN, NAG

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2YP3 \| pdb_00002yp3	Download File View File

Haemagglutinin of 2004 Human H3N2 Virus in Complex with Human Receptor Analogue 6SLN

Xiong, X., Lin, Y.P., Wharton, S.A., Martin, S.R., Coombs, P.J., Vachieri, S.G., Christodoulou, E., Walker, P.A., Liu, J., Skehel, J.J., Gamblin, S.J., Hay, A.J., Daniels, R.S., McCauley, J.W.

(2012) Proc Natl Acad Sci U S A 109: 21474

Released	2012-11-07
Method	X-RAY DIFFRACTION 1.88 Å
Organisms	Influenza A virus
Macromolecule	HEMAGGLUTININ (protein)
Unique Ligands	EPE, NAG, TAM
Unique branched monosaccharides	GAL, MAN, NAG, SIA

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2YP4 \| pdb_00002yp4	Download File View File

Haemagglutinin of 2004 Human H3N2 Virus in Complex with Human Receptor Analogue LSTc

Xiong, X., Lin, Y.P., Wharton, S.A., Martin, S.R., Coombs, P.J., Vachieri, S.G., Christodoulou, E., Walker, P.A., Liu, J., Skehel, J.J., Gamblin, S.J., Hay, A.J., Daniels, R.S., McCauley, J.W.

(2012) Proc Natl Acad Sci U S A 109: 21474

Released	2012-11-07
Method	X-RAY DIFFRACTION 1.85 Å
Organisms	Influenza A virus
Macromolecule	HEMAGGLUTININ (protein)
Unique Ligands	EPE, NAG, TAM
Unique branched monosaccharides	BGC, GAL, MAN, NAG, SIA

Explore in 3D

2YP5 \| pdb_00002yp5	Download File View File

Haemagglutinin of 2004 Human H3N2 Virus in Complex with Avian Receptor Analogue 3SLN

Xiong, X., Lin, Y.P., Wharton, S.A., Martin, S.R., Coombs, P.J., Vachieri, S.G., Christodoulou, E., Walker, P.A., Liu, J., Skehel, J.J., Gamblin, S.J., Hay, A.J., Daniels, R.S., McCauley, J.W.

(2012) Proc Natl Acad Sci U S A 109: 21474

Released	2012-11-07
Method	X-RAY DIFFRACTION 1.79 Å
Organisms	Influenza A virus (A/Finland/486/2004 (H3N2))
Macromolecule	HEMAGGLUTININ (protein)
Unique Ligands	EPE, NAG, TAM
Unique branched monosaccharides	GAL, MAN, NAG, SIA

Explore in 3D

2YP7 \| pdb_00002yp7	Download File View File

Haemagglutinin of 2005 Human H3N2 Virus

Xiong, X., Lin, Y.P., Wharton, S.A., Martin, S.R., Coombs, P.J., Vachieri, S.G., Christodoulou, E., Walker, P.A., Liu, J., Skehel, J.J., Gamblin, S.J., Hay, A.J., Daniels, R.S., McCauley, J.W.

(2012) Proc Natl Acad Sci U S A 109: 21474

Released	2012-11-07
Method	X-RAY DIFFRACTION 1.85 Å
Organisms	Influenza A virus
Macromolecule	HEMAGGLUTININ (protein)
Unique Ligands	EPE, NAG, TAM
Unique branched monosaccharides	MAN, NAG

Explore in 3D

2YP8 \| pdb_00002yp8	Download File View File

Haemagglutinin of 2005 Human H3N2 Virus in Complex with Human Receptor Analogue 6SLN

Xiong, X., Lin, Y.P., Wharton, S.A., Martin, S.R., Coombs, P.J., Vachieri, S.G., Christodoulou, E., Walker, P.A., Liu, J., Skehel, J.J., Gamblin, S.J., Hay, A.J., Daniels, R.S., McCauley, J.W.

(2012) Proc Natl Acad Sci U S A 109: 21474

Released	2012-11-07
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Influenza A virus
Macromolecule	HEMAGGLUTININ (protein)
Unique Ligands	EPE, NAG, SIA, TAM
Unique branched monosaccharides	MAN, NAG

Explore in 3D

2YP9 \| pdb_00002yp9	Download File View File

Haemagglutinin of 2005 Human H3N2 Virus in Complex with Avian Receptor Analogue 3SLN

Xiong, X., Lin, Y.P., Wharton, S.A., Martin, S.R., Coombs, P.J., Vachieri, S.G., Christodoulou, E., Walker, P.A., Liu, J., Skehel, J.J., Gamblin, S.J., Hay, A.J., Daniels, R.S., McCauley, J.W.

(2012) Proc Natl Acad Sci U S A 109: 21474

Released	2012-11-07
Method	X-RAY DIFFRACTION 1.79 Å
Organisms	Influenza A virus
Macromolecule	HEMAGGLUTININ (protein)
Unique Ligands	CMO, EPE, NAG, SIA, TAM
Unique branched monosaccharides	MAN, NAG

Explore in 3D

2YPG \| pdb_00002ypg	Download File View File

Haemagglutinin of 1968 Human H3N2 Virus in Complex with Human Receptor Analogue LSTc

Liu, J., Xiong, X., Haire, L.F., Lin, Y.P., Wharton, S.A., Martin, S.R., Coombs, P.J., Vachieri, S.G., Christodoulou, E., Walker, P.A., Skehel, J.J., Gamblin, S.J., Hay, A.J., Daniels, R.S., McCauley, J.W.

(2012) Proc Natl Acad Sci U S A 109: 21474

Released	2012-11-07
Method	X-RAY DIFFRACTION 2.85 Å
Organisms	Influenza A virus (A/X-31(H3N2))
Macromolecule	HEMAGGLUTININ HA1 CHAIN (protein) HEMAGGLUTININ HA2 CHAIN (protein)
Unique Ligands	FLC, NAG
Unique branched monosaccharides	BGC, BMA, FUL, GAL, NAG, SIA

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3CKZ \| pdb_00003ckz	Download File View File

N1 Neuraminidase H274Y + Zanamivir

Colllins, P., Haire, L.F., Lin, Y.P., Liu, J., Russell, R.J., Walker, P.A., Skehel, J.J., Martin, S.R., Hay, A.J., Gamblin, S.J.

(2008) Nature 453: 1258-1261

Released	2008-05-20
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Influenza A virus (A/Viet Nam/1203/2004(H5N1))
Macromolecule	Neuraminidase (protein)
Unique Ligands	CA, ZMR

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3CL0 \| pdb_00003cl0	Download File View File

N1 Neuraminidase H274Y + oseltamivir

Collins, P., Haire, L.F., Lin, Y.P., Liu, J., Russell, R.J., Walker, P.A., Skehel, J.J., Martin, S.R., Hay, A.J., Gamblin, S.J.

(2008) Nature 453: 1258-1261

Released	2008-05-20
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Influenza A virus (A/Viet Nam/1203/2004(H5N1))
Macromolecule	Neuraminidase (protein)
Unique Ligands	CA, G39

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3CL2 \| pdb_00003cl2	Download File View File

N1 Neuraminidase N294S + Oseltamivir

Collins, P., Haire, L.F., Lin, Y.P., Liu, J., Russell, R.J., Walker, P.A., Skehel, J.J., Martin, S.R., Hay, A.J., Gamblin, S.J.

(2008) Nature 453: 1258-1261

Released	2008-05-20
Method	X-RAY DIFFRACTION 2.538 Å
Organisms	Influenza A virus (A/Viet Nam/1203/2004(H5N1))
Macromolecule	Neuraminidase (protein)
Unique Ligands	G39

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3ZP0 \| pdb_00003zp0	Download File View File

INFLUENZA VIRUS (VN1194) H5 HA with LSTa

Liu, J., Stevens, D.J., Gamblin, S.J., Skehel, J.J.

(2013) Virology 447: 326

Released	2013-10-02
Method	X-RAY DIFFRACTION 2.51 Å
Organisms	Influenza A virus
Macromolecule	HEMAGGLUTININ (protein)
Unique Ligands	NAG
Unique branched monosaccharides	GAL, SIA

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3ZP1 \| pdb_00003zp1	Download File View File

INFLUENZA VIRUS (VN1194) H5 HA with LSTc

Liu, J., Stevens, D.J., Gamblin, S.J., Skehel, J.J.

(2013) Virology 447: 326

Released	2013-10-02
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Influenza A virus
Macromolecule	HAEMAGGLUTININ (protein)
Unique branched monosaccharides	GAL, SIA

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3ZP2 \| pdb_00003zp2	Download File View File

INFLUENZA VIRUS (VN1194) H5 HA A138V mutant with LSTa

Liu, J., Stevens, D.J., Gamblin, S.J., Skehel, J.J.

(2013) Virology 447: 326

Released	2013-10-02
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Influenza A virus
Macromolecule	HAEMAGGLUTININ (protein)
Unique Ligands	NAG
Unique branched monosaccharides	GAL, SIA

1 to 25 of 34 Structures

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type

SCOP Classification

2HT5 | pdb_00002ht5

2HT7 | pdb_00002ht7

2HT8 | pdb_00002ht8

2HTQ | pdb_00002htq

2HTR | pdb_00002htr

2HTU | pdb_00002htu

2HTV | pdb_00002htv

2HTW | pdb_00002htw

2HTY | pdb_00002hty

2HU0 | pdb_00002hu0

2HU4 | pdb_00002hu4

2YP2 | pdb_00002yp2

2YP3 | pdb_00002yp3

2YP4 | pdb_00002yp4

2YP5 | pdb_00002yp5

2YP7 | pdb_00002yp7

2YP8 | pdb_00002yp8

2YP9 | pdb_00002yp9

2YPG | pdb_00002ypg

3CKZ | pdb_00003ckz

3CL0 | pdb_00003cl0

3CL2 | pdb_00003cl2

3ZP0 | pdb_00003zp0

3ZP1 | pdb_00003zp1

3ZP2 | pdb_00003zp2