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234,785 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Citation Author = "Briza, P."

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Search Summary

This query matches 116 Structures.

Refinements

Structure Determination Methodology

experimental (116)

Scientific Name of Source Organism

	Homo sapiens (62)
	Severe acute respiratory syndrome coronavirus 2 (13)
	Gallus gallus (7)
	Rattus norvegicus (7)
	Escherichia phage Lambda (5)
	Neisseria meningitidis MC58 (5)
	Saccharomyces cerevisiae S288C (5)
	Bos taurus (4)
	Drosophila melanogaster (4)
	Proteus mirabilis (4)

More...

Taxonomy

	Eukaryota (87)
	Bacteria (14)
	Riboviria (13)
	Duplodnaviria (7)
	other sequences (2)

Experimental Method

	X-RAY DIFFRACTION (91)
	ELECTRON MICROSCOPY (25)

Polymer Entity Type

	Protein (116)
	RNA (10)

Refinement Resolution (Å)

	1.0 - 1.5 (2)
	1.5 - 2.0 (21)
	2.0 - 2.5 (41)
	2.5 - 3.0 (24)
	3.0 - 3.5 (22)
	3.5 - 4.0 (5)
	4.0 - 4.5 (1)

Release Date

	2010 - 2014 (18)
	2015 - 2019 (24)
	2020 - 2024 (73)
	2025 - 2029 (1)

Enzyme Classification Name

	Transferases (49)
	Hydrolases (19)
	Ligases (3)
	Isomerases (1)

Membrane Protein Annotation

	OPM (2)
	MemProtMD (1)
	PDBTM (1)
	mpstruc (1)

Symmetry Type

	Asymmetric (80)
	Cyclic (31)
	Dihedral (5)
	Octahedral (2)

SCOP Classification

	Alpha and beta proteins (a+b) (34)
	Alpha and beta proteins (a/b) (6)
	Artifacts (12)
	All alpha proteins (5)
	All beta proteins (1)
	Membrane and cell surface proteins and peptides (1)

AllSelected

1 to 25 of 116 Structures

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2YBY \| pdb_00002yby	Download File View File

Structure of domains 6 and 7 of the mouse complement regulator Factor H

Everett, R.J., Caesar, J.J.E., Johnson, S.J., Tang, C.M., Lea, S.M.

(2012) PLoS Pathog 8: 2981

Released	2012-04-18
Method	X-RAY DIFFRACTION 1.58 Å
Organisms	Mus musculus
Macromolecule	COMPLEMENT FACTOR H (protein)
Unique Ligands	EDO

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3ZTX \| pdb_00003ztx	Download File View File

Aurora kinase selective inhibitors identified using a Taxol-induced checkpoint sensitivity screen.

Kwiatkowski, N., Villa, F., Musacchio, A., Gray, N.

(2012) ACS Chem Biol 7: 185

Released	2012-02-01
Method	X-RAY DIFFRACTION 1.95 Å
Organisms	Xenopus laevis
Macromolecule	INNER CENTROMERE PROTEIN A (protein) SERINE/THREONINE-PROTEIN KINASE 12-A (protein)
Unique Ligands	ZTX

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4AYD \| pdb_00004ayd	Download File View File

Structure of a complex between CCPs 6 and 7 of Human Complement Factor H and Neisseria meningitidis FHbp Variant 1 R106A mutant

Johnson, S., Tan, L., van der Veen, S., Caesar, J., Goicoechea De Jorge, E., Everett, R.J., Bai, X., Exley, R.M., Ward, P.N., Ruivo, N., Trivedi, K., Cumber, E., Jones, R., Newham, L., Staunton, D., Borrow, R., Pickering, M., Lea, S.M., Tang, C.M.

(2012) PLoS Pathog 8: 2981

Released	2012-11-07
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Homo sapiens Neisseria meningitidis MC58
Macromolecule	COMPLEMENT FACTOR H (protein) FACTOR H BINDING PROTEIN (protein)
Unique Ligands	EDO

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4AYE \| pdb_00004aye	Download File View File

Structure of a complex between CCPs 6 and 7 of Human Complement Factor H and Neisseria meningitidis FHbp Variant 1 E283AE304A mutant

(2012) PLoS Pathog 8: 2981

Released	2012-11-07
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Homo sapiens Neisseria meningitidis MC58
Macromolecule	COMPLEMENT FACTOR H (protein) FACTOR H BINDING PROTEIN (protein)
Unique Ligands	EDO

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4AYI \| pdb_00004ayi	Download File View File

Structure of a complex between CCPs 6 and 7 of Human Complement Factor H and Neisseria meningitidis FHbp Variant 3 Wild type

(2012) PLoS Pathog 8: 2981

Released	2012-11-07
Method	X-RAY DIFFRACTION 2.31 Å
Organisms	Homo sapiens Neisseria meningitidis MC58
Macromolecule	COMPLEMENT FACTOR H (protein) LIPOPROTEIN GNA1870 CCOMPND 7 (protein)
Unique Ligands	EDO

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4AYM \| pdb_00004aym	Download File View File

Structure of a complex between CCPs 6 and 7 of Human Complement Factor H and Neisseria meningitidis FHbp Variant 3 P106A mutant

(2012) PLoS Pathog 8: 2981

Released	2012-11-07
Method	X-RAY DIFFRACTION 3 Å
Organisms	Homo sapiens Neisseria meningitidis MC58
Macromolecule	COMPLEMENT FACTOR H (protein) FACTOR H BINDING PROTEIN (protein)

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4AYN \| pdb_00004ayn	Download File View File

Structure of the C-terminal barrel of Neisseria meningitidis FHbp Variant 2

(2012) PLoS Pathog 8: 2981

Released	2012-11-07
Method	X-RAY DIFFRACTION 2.06 Å
Organisms	Neisseria meningitidis MC58
Macromolecule	FACTOR H-BINDING PROTEIN (protein)
Unique Ligands	SO4

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4CKR \| pdb_00004ckr	Download File View File

Crystal structure of the human DDR1 kinase domain in complex with DDR1-IN-1

Canning, P., Elkins, J.M., Goubin, S., Mahajan, P., Krojer, T., Newman, J.A., Dixon-Clarke, S., Chaikuad, A., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Bullock, A.

(2013) ACS Chem Biol 8: 2145

Released	2014-01-15
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Homo sapiens
Macromolecule	EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1 (protein)
Unique Ligands	DI1, EDO

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4L3I \| pdb_00004l3i	Download File View File

Structure of the microtubule associated protein PRC1 (Protein Regulator of Cytokinesis 1)

Subramanian, R., Ti, S., Tan, L., Darst, S.A., Kapoor, T.M.

(2013) Cell 154: 377-390

Released	2013-07-17
Method	X-RAY DIFFRACTION 3.6005 Å
Organisms	Homo sapiens
Macromolecule	Protein regulator of cytokinesis 1 (protein)

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4L6Y \| pdb_00004l6y	Download File View File

Structure of the microtubule associated protein PRC1 (Protein Regulator of Cytokinesis 1)

Subramanian, R., Ti, S., Tan, L., Darst, S.A., Kapoor, T.M.

(2013) Cell 154: 377-390

Released	2013-07-17
Method	X-RAY DIFFRACTION 3.3015 Å
Organisms	Homo sapiens
Macromolecule	Protein regulator of cytokinesis 1 (protein)

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4O91 \| pdb_00004o91	Download File View File

Crystal Structure of type II inhibitor NG25 bound to TAK1-TAB1

Gurbani, D., Hunter, J.C., Tan, L., Westover, K.D.

(2015) J Med Chem 58: 183-196

Released	2014-07-30
Method	X-RAY DIFFRACTION 2.393 Å
Organisms	Homo sapiens
Macromolecule	Mitogen-activated protein kinase kinase kinase 7/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 chimera (protein)
Unique Ligands	NG2

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4QQ5 \| pdb_00004qq5	Download File View File

Crystal Structure of FGF Receptor (FGFR) 4 Kinase Harboring the V550L Gate-Keeper Mutation in Complex With FIIN-2, an Irreversible Tyrosine Kinase Inhibitor Capable of Overcoming FGFR Kinase Gate-Keeper Mutations

Huang, Z., Mohammadi, M.

(2015) ACS Chem Biol 10: 299-309

Released	2014-10-29
Method	X-RAY DIFFRACTION 2.203 Å
Organisms	Homo sapiens
Macromolecule	Fibroblast growth factor receptor 4 (protein)
Unique Ligands	37O

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4QQC \| pdb_00004qqc	Download File View File

Crystal Structure of FGF Receptor (FGFR) 4 Kinase Domain in Complex with FIIN-2, an Irreversible Tyrosine Kinase Inhibitor Capable of Overcoming FGFR Kinase Gate-Keeper Mutations

Huang, Z., Mohammadi, M.

(2014) Proc Natl Acad Sci U S A 111: E4869-E4877

Released	2014-10-29
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Homo sapiens
Macromolecule	Fibroblast growth factor receptor 4 (protein)
Unique Ligands	37O, SO4

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4QQJ \| pdb_00004qqj	Download File View File

Crystal Structure of FGF Receptor (FGFR) 4 Kinase Domain Harboring the V550L Gate-Keeper Mutation

Huang, Z., Mohammadi, M.

(2015) ACS Chem Biol 10: 299-309

Released	2014-10-29
Method	X-RAY DIFFRACTION 1.682 Å
Organisms	Homo sapiens
Macromolecule	Fibroblast growth factor receptor 4 (protein)
Unique Ligands	SO4

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4QQT \| pdb_00004qqt	Download File View File

Crystal Structure of FGF Receptor (FGFR) 4 Tyrosine Kinase Domain

Huang, Z., Mohammadi, M.

(2015) ACS Chem Biol 10: 299-309

Released	2014-10-29
Method	X-RAY DIFFRACTION 1.501 Å
Organisms	Homo sapiens
Macromolecule	Fibroblast growth factor receptor 4 (protein)
Unique Ligands	SO4

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4QRC \| pdb_00004qrc	Download File View File

Crystal Structure of the Tyrosine Kinase Domain of FGF Receptor 4 in Complex with Ponatinib

Huang, Z., Mohammadi, M.

(2015) ACS Chem Biol 10: 299-309

Released	2014-10-29
Method	X-RAY DIFFRACTION 1.901 Å
Organisms	Homo sapiens
Macromolecule	Fibroblast growth factor receptor 4 (protein)
Unique Ligands	0LI, SO4

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4R5S \| pdb_00004r5s	Download File View File

Crystal structure of EGFR 696-1022 L858R in complex with FIIN-3

Zhu, S.J., Yun, C.H.

(2014) Proc Natl Acad Sci U S A 111: E4869-E4877

Released	2014-11-12
Method	X-RAY DIFFRACTION 3.001 Å
Organisms	Homo sapiens
Macromolecule	Epidermal growth factor receptor (protein)
Unique Ligands	FI3

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4R6V \| pdb_00004r6v	Download File View File

Crystal Structure of FGF Receptor (FGFR) 4 Kinase Harboring the V550L Gate-Keeper Mutation in Complex with FIIN-3, an Irreversible Tyrosine Kinase Inhibitor Capable of Overcoming FGFR kinase Gate-Keeper Mutations

Huang, Z., Mohammadi, M.

(2014) Proc Natl Acad Sci U S A 111: E4869-E4877

Released	2014-10-29
Method	X-RAY DIFFRACTION 2.353 Å
Organisms	Homo sapiens
Macromolecule	Fibroblast growth factor receptor 4 (protein)
Unique Ligands	FI3, SO4

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4Z16 \| pdb_00004z16	Download File View File

Crystal Structure of the Jak3 Kinase Domain Covalently Bound to N-(3-(((5-chloro-2-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)amino)methyl)phenyl)acrylamide

McNally, R., Tan, L., Gray, N.S., Eck, M.J.

(2015) J Med Chem 58: 6589-6606

Released	2016-02-10
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Homo sapiens
Macromolecule	Tyrosine-protein kinase JAK3 (protein)
Unique Ligands	4LH

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5E7R \| pdb_00005e7r	Download File View File

Crystal structure of TL10-81 bound to TAK1-TAB1

Gurbani, D., Hunter, J.C., Tan, L., Chen, Z., Westover, K.D.

(2017) Bioorg Med Chem 25: 838-846

Released	2016-09-21
Method	X-RAY DIFFRACTION 2.11 Å
Organisms	Homo sapiens
Macromolecule	TAK1 kinase - TAB1 chimera fusion protein (protein)
Unique Ligands	5KW

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5EK5 \| pdb_00005ek5	Download File View File

STRUCTURAL CHARACTERIZATION OF IRMA FROM ESCHERICHIA COLI

Heras, B., Moriel, D.G., Paxman, J.J., Schembri, M.A.

(2016) mBio 7: e02046-e02046

Released	2016-03-09
Method	X-RAY DIFFRACTION 2.26 Å
Organisms	Escherichia coli CFT073
Macromolecule	IRMA (protein)
Unique Ligands	CL, EDO, FMT, NA

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5J7S \| pdb_00005j7s	Download File View File

Crystal structure of SM1-71 bound to TAK1-TAB1

Gurbani, D., Westover, K.D.

(2017) Bioorg Med Chem 25: 838-846

Released	2017-02-15
Method	X-RAY DIFFRACTION 2.368 Å
Organisms	Homo sapiens
Macromolecule	Mitogen-activated protein kinase kinase kinase 7/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 chimera (protein)
Unique Ligands	6H3

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5J8I \| pdb_00005j8i	Download File View File

Crystal structure of TL11-113 bound to TAK1-TAB1

Gurbani, D., Westover, K.D.

(2017) Bioorg Med Chem 25: 838-846

Released	2017-02-15
Method	X-RAY DIFFRACTION 2.404 Å
Organisms	Homo sapiens
Macromolecule	Mitogen-activated protein kinase kinase kinase 7/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 chimera (protein)
Unique Ligands	6H4

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5J9L \| pdb_00005j9l	Download File View File

Crystal structure of CPT1691 bound to TAK1-TAB1

Gurbani, D., Westover, K.D.

(2017) Bioorg Med Chem 25: 838-846

Released	2017-02-15
Method	X-RAY DIFFRACTION 2.7515 Å
Organisms	Homo sapiens
Macromolecule	Mitogen-activated protein kinase kinase kinase 7,TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 (protein)
Unique Ligands	6HF

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5JH6 \| pdb_00005jh6	Download File View File

Crystal structure of TL10-92 bound to TAK1-TAB1

Gurbani, D., Westover, K.D.

(2017) Bioorg Med Chem 25: 838-846

Released	2017-02-15
Method	X-RAY DIFFRACTION 2.365 Å
Organisms	Homo sapiens
Macromolecule	Mitogen-activated protein kinase kinase kinase 7,TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 (protein)
Unique Ligands	T92

1 to 25 of 116 Structures

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification

2YBY | pdb_00002yby

3ZTX | pdb_00003ztx

4AYD | pdb_00004ayd

4AYE | pdb_00004aye

4AYI | pdb_00004ayi

4AYM | pdb_00004aym

4AYN | pdb_00004ayn

4CKR | pdb_00004ckr

4L3I | pdb_00004l3i

4L6Y | pdb_00004l6y

4O91 | pdb_00004o91

4QQ5 | pdb_00004qq5

4QQC | pdb_00004qqc

4QQJ | pdb_00004qqj

4QQT | pdb_00004qqt

4QRC | pdb_00004qrc

4R5S | pdb_00004r5s

4R6V | pdb_00004r6v

4Z16 | pdb_00004z16

5E7R | pdb_00005e7r

5EK5 | pdb_00005ek5

5J7S | pdb_00005j7s

5J8I | pdb_00005j8i

5J9L | pdb_00005j9l

5JH6 | pdb_00005jh6