QUERY: Structure Author = "Whitlow, M."
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Search Summary This query matches 72 Structures.
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1 to 25 of 72 Structures
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1A2Q | pdb_00001a2q

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SUBTILISIN BPN' MUTANT 7186

Gilliland, G.L., Whitlow, M., Howard, A.J.

(1989) Biochemistry 28: 7205-7213

Released1998-04-29
Method
X-RAY DIFFRACTION 1.8 Å
Organisms
Macromolecule
Unique LigandsACN, CA
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1AI9 | pdb_00001ai9

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CANDIDA ALBICANS DIHYDROFOLATE REDUCTASE

Whitlow, M., Howard, A.J., Stewart, D.

(1997) J Biological Chem 272: 30289-30298

Released1997-11-12
Method
X-RAY DIFFRACTION 1.85 Å
Organisms
Macromolecule
Unique LigandsNDP
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1AK9 | pdb_00001ak9

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SUBTILISIN MUTANT 8321

Whitlow, M., Howard, A.J., Wood, J.F.

(1989) Biochemistry 28: 7205-7213

Released1997-11-12
Method
X-RAY DIFFRACTION 1.8 Å
Organisms
Macromolecule
Unique LigandsCA, IPA, NA
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1AOE | pdb_00001aoe

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CANDIDA ALBICANS DIHYDROFOLATE REDUCTASE COMPLEXED WITH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (NADPH) AND 1,3-DIAMINO-7-(1-ETHYEPROPYE)-7H-PYRRALO-[3,2-F]QUINAZOLINE (GW345)

Whitlow, M., Howard, A.J., Stewart, D.

(1997) J Biological Chem 272: 30289-30298

Released1998-01-07
Method
X-RAY DIFFRACTION 1.6 Å
Organisms
Macromolecule
Unique LigandsGW3, NDP
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1AQN | pdb_00001aqn

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SUBTILISIN MUTANT 8324

Whitlow, M., Howard, A.J., Wood, J.F.

To be published

Released1998-01-14
Method
X-RAY DIFFRACTION 1.8 Å
Organisms
Macromolecule
Unique LigandsCA, IPA, UNX
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1AU9 | pdb_00001au9

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SUBTILISIN BPN' MUTANT 8324 IN CITRATE

Whitlow, M., Howard, A.J., Wood, J.F.

(1989) Biochemistry 28: 7205-7213

Released1997-12-31
Method
X-RAY DIFFRACTION 1.8 Å
Organisms
Macromolecule
Unique LigandsCA, IPA, UNX
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1DD7 | pdb_00001dd7

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MURINE INDUCIBLE NITRIC OXIDE SYNTHASE OXYGENASE DOMAIN (DELTA 114) (N-[(1,3-BENZODIOXOL-5-YL)METHYL]-1-[2-(1H-IMIDAZOL-1-YL)PYRIMIDIN-4-YL]-4-(METHOXYCARBONYL)-PIPERAZINE-2-ACETAMIDE COMPLEX

Adler, M., Whitlow, M.

(2000) Proc Natl Acad Sci U S A 97: 1506-1511

Released2000-03-29
Method
X-RAY DIFFRACTION 2.25 Å
Organisms
Macromolecule
Unique Ligands1PM, HEM, SO3
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1FJS | pdb_00001fjs

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CRYSTAL STRUCTURE OF THE INHIBITOR ZK-807834 (CI-1031) COMPLEXED WITH FACTOR XA

Adler, M., Whitlow, M.

(2000) Biochemistry 39: 12534-12542

Released2000-10-04
Method
X-RAY DIFFRACTION 1.92 Å
Organisms
Macromolecule
Unique LigandsCA, CL, GOL, Z34
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1FLR | pdb_00001flr

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4-4-20 FAB FRAGMENT

Whitlow, M.

(1995) Protein Eng 8: 749-761

Released1995-09-15
Method
X-RAY DIFFRACTION 1.85 Å
Organisms
Macromolecule
Unique LigandsFLU
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1IA1 | pdb_00001ia1

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Candida albicans dihydrofolate reductase complexed with dihydro-nicotinamide-adenine-dinucleotide phosphate (NADPH) and 5-(PHENYLSULFANYL)-2,4-QUINAZOLINEDIAMINE (GW997)

Whitlow, M., Howard, A.J., Kuyper, L.F.

(2001) J Med Chem 44: 2928-2932

Released2001-04-11
Method
X-RAY DIFFRACTION 1.7 Å
Organisms
Macromolecule
Unique LigandsNDP, PO4, TQ3
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1IA2 | pdb_00001ia2

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Candida albicans dihydrofolate reductase complexed with dihydro-nicotinamide-adenine-dinucleotide phosphate (NADPH) and 5-[(4-METHYLPHENYL)SULFANYL]-2,4-QUINAZOLINEDIAMINE (GW578)

Whitlow, M., Howard, A.J., Kuyper, L.F.

(2001) J Med Chem 44: 2928-2932

Released2001-04-11
Method
X-RAY DIFFRACTION 1.82 Å
Organisms
Macromolecule
Unique LigandsMES, NDP, TQ4
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1IA3 | pdb_00001ia3

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Candida albicans dihydrofolate reductase complex in which the dihydronicotinamide moiety of dihydro-nicotinamide-adenine-dinucleotide phosphate (NADPH) is displaced by 5-[(4-TERT-BUTYLPHENYL)SULFANYL]-2,4-QUINAZOLINEDIAMINE (GW995)

Whitlow, M., Howard, A.J., Kuyper, L.F.

(2001) J Med Chem 44: 2928-2932

Released2001-04-11
Method
X-RAY DIFFRACTION 1.78 Å
Organisms
Macromolecule
Unique LigandsMES, NDP, TQ5
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1IA4 | pdb_00001ia4

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Candida albicans dihydrofolate reductase complex in which the dihydronicotinamide moiety of dihydro-nicotinamide-adenine-dinucleotide phosphate (NADPH) is displaced by 5-{[4-(4-MORPHOLINYL)PHENYL]SULFANYL}-2,4-QUINAZOLINEDIAMIN (GW2021)

Whitlow, M., Howard, A.J., Kuyper, L.F.

(2001) J Med Chem 44: 2928-2932

Released2001-04-11
Method
X-RAY DIFFRACTION 1.85 Å
Organisms
Macromolecule
Unique LigandsMES, NDP, TQ6
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1KRN | pdb_00001krn

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STRUCTURE OF KRINGLE 4 AT 4C TEMPERATURE AND 1.67 ANGSTROMS RESOLUTION

Stec, B., Teeter, M.M., Whitlow, M., Yamano, A.

(1997) Acta Crystallogr D Biol Crystallogr 53: 169-178

Released1997-01-11
Method
X-RAY DIFFRACTION 1.67 Å
Organisms
Macromolecule
PLASMINOGEN (protein)
Unique LigandsSO4
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1M78 | pdb_00001m78

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CANDIDA ALBICANS DIHYDROFOLATE REDUCTASE COMPLEXED WITH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (NADPH) AND 5-CHLORYL-2,4,6-QUINAZOLINETRIAMINE (GW1225)

Whitlow, M., Howard, A.J., Kuyper, L.F.

(1997) J Biological Chem 272: 30289-30298

Released2003-03-04
Method
X-RAY DIFFRACTION 1.71 Å
Organisms
Macromolecule
Unique LigandsCLZ, NDP
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1M79 | pdb_00001m79

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Candida albicans Dihydrofolate Reductase Complexed with Dihydro-Nicotinamide-Adenine-Dinucleotide Phosphate (NADPH) and 5-(4-methoxyphenoxy)-2,4-quinazolinediamine (GW1466)

Whitlow, M., Howard, A.J., Kuyper, L.F.

(1997) J Biological Chem 272: 30289-30298

Released2003-03-04
Method
X-RAY DIFFRACTION 1.7 Å
Organisms
Macromolecule
Unique LigandsMES, MQ1, NDP
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1M7A | pdb_00001m7a

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CANDIDA ALBICANS DIHYDROFOLATE REDUCTASE COMPLEXED WITH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (NADPH) AND 7-[2-methoxy-1-(methoxymethyl)ethyl]-7H-pyrrolo[3,2-f] quinazoline-1,3-diamine (GW557)

Whitlow, M., Howard, A.J., Kuyper, L.F.

(1997) J Biological Chem 272: 30289-30298

Released2003-03-04
Method
X-RAY DIFFRACTION 1.76 Å
Organisms
Macromolecule
Unique LigandsMQU, NDP
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1MQ5 | pdb_00001mq5

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Crystal Structure of 3-chloro-N-[4-chloro-2-[[(4-chlorophenyl)amino]carbonyl]phenyl]-4-[(4-methyl-1-piperazinyl)methyl]-2-thiophenecarboxamide Complexed with Human Factor Xa

Adler, M., Whitlow, M.

(2002) Biochemistry 41: 15514-15523

Released2003-01-28
Method
X-RAY DIFFRACTION 2.1 Å
Organisms
Macromolecule
Unique LigandsCA, GOL, XLC
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1MQ6 | pdb_00001mq6

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Crystal Structure of 3-chloro-N-[4-chloro-2-[[(5-chloro-2-pyridinyl)amino]carbonyl]-6-methoxyphenyl]-4-[[(4,5-dihydro-2-oxazolyl)methylamino]methyl]-2-thiophenecarboxamide Complexed with Human Factor Xa

Adler, M., Whitlow, M.

(2002) Biochemistry 41: 15514-15523

Released2003-01-28
Method
X-RAY DIFFRACTION 2.1 Å
Organisms
Macromolecule
Unique LigandsCA, GOL, XLD
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1NSI | pdb_00001nsi

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HUMAN INDUCIBLE NITRIC OXIDE SYNTHASE, ZN-BOUND, L-ARG COMPLEX

Li, H., Raman, C.S., Glaser, C.B., Blasko, E., Young, T.A., Parkinson, J.F., Whitlow, M., Poulos, T.L.

(1999) J Biological Chem 274: 21276-21284

Released2000-01-07
Method
X-RAY DIFFRACTION 2.55 Å
Organisms
Macromolecule
Unique LigandsARG, GOL, H4B, HEM, SO4, ZN
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1PGX | pdb_00001pgx

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THE 1.66 ANGSTROMS X-RAY STRUCTURE OF THE B2 IMMUNOGLOBULIN-BINDING DOMAIN OF STREPTOCOCCAL PROTEIN G AND COMPARISON TO THE NMR STRUCTURE OF THE B1 DOMAIN

Whitlow, M., Achari, A., Howard, A.J.

(1992) Biochemistry 31: 10449-10457

Released1992-07-15
Method
X-RAY DIFFRACTION 1.66 Å
Organisms
Macromolecule
PROTEIN G (protein)
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1QA0 | pdb_00001qa0

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BOVINE TRYPSIN 2-AMINOBENZIMIDAZOLE COMPLEX

Whitlow, M.

(1999) Acta Crystallogr D Biol Crystallogr 55: 1395-1404

Released2000-04-10
Method
X-RAY DIFFRACTION 1.8 Å
Organisms
Macromolecule
TRYPSIN (protein)
Unique Ligands270, CA
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1QB1 | pdb_00001qb1

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Bovine Trypsin with 1-[2-[5-[amino(imino)methyl]-2-hydroxyphenoxy]-6-[3-(4,5-dihydro-1-methyl-1H-imidazol-2-yl)phenoxy]pyridin-4-yl]piperidine-3-carboxylic Acid (ZK-806974)

Whitlow, M.

(1999) Acta Crystallogr D Biol Crystallogr 55: 1395-1404

Released2000-04-29
Method
X-RAY DIFFRACTION 1.8 Å
Organisms
Macromolecule
Unique Ligands974, CA
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1QB6 | pdb_00001qb6

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BOVINE TRYPSIN 3,3'-[3,5-DIFLUORO-4-METHYL-2, 6-PYRIDINEDIYLBIS(OXY)]BIS(BENZENECARBOXIMIDAMIDE) (ZK-805623) COMPLEX

Whitlow, M.

(1999) Acta Crystallogr D Biol Crystallogr 55: 1395-1404

Released2000-04-29
Method
X-RAY DIFFRACTION 1.8 Å
Organisms
Macromolecule
Unique Ligands623, CA, K
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1QB9 | pdb_00001qb9

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BOVINE TRYPSIN 7-[[2-[[1-(1-IMINOETHYL)PIPERIDIN-4-YL]OXY]-9H-CARBOZOL-9-YL] METHYL]NAPHTHALENE-2-CARBOXIMIDAMIDE (ZK-806450) COMPLEX

Whitlow, M.

(1999) Acta Crystallogr D Biol Crystallogr 55: 1395-1404

Released2000-04-30
Method
X-RAY DIFFRACTION 1.8 Å
Organisms
Macromolecule
Unique Ligands806, CA, K
1 to 25 of 72 Structures
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