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234,440 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Structure Author = "Hazuda, D."

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Search Summary

This query matches 14 Structures.

Refinements

Structure Determination Methodology

experimental (14)

Scientific Name of Source Organism

	Homo sapiens (10)
	Corynebacterium diphtheriae (3)
	Bos taurus (1)

Taxonomy

	Eukaryota (11)
	Bacteria (3)
	Eukaryota (eukaryotes) (1)

Experimental Method

	X-RAY DIFFRACTION (9)
	SOLUTION NMR (5)

Polymer Entity Type

Protein (14)

Refinement Resolution (Å)

1.5 - 2.0 (9)

Release Date

	1990 - 1994 (1)
	1995 - 1999 (2)
	2000 - 2004 (10)
	2005 - 2009 (1)

Enzyme Classification Name

Hydrolases (1)

Symmetry Type

	Asymmetric (14)
	Cyclic (2)

SCOP Classification

	All beta proteins (12)
	Artifacts (9)
	Alpha and beta proteins (a+b) (1)
	Alpha and beta proteins (a/b) (1)

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1 to 14 of 14 Structures

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1BVH \| pdb_00001bvh	Download File View File

SOLUTION STRUCTURE OF A LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE

Logan, T.M., Zhou, M.-M., Nettesheim, D.G., Meadows, R.P., Van Etten, R.L., Fesik, S.W.

(1994) Biochemistry 33: 11087-11096

Released	1994-07-31
Method	SOLUTION NMR
Organisms	Bos taurus
Macromolecule	ACID PHOSPHATASE (protein)

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1BYM \| pdb_00001bym	Download File View File

SOLUTION STRUCTURES OF THE C-TERMINAL DOMAIN OF DIPHTHERIA TOXIN REPRESSOR

Wang, G., Wylie, G.P., Twigg, P.D., Caspar, D.L.D., Murphy, J.R., Logan, T.M.

(1999) Proc Natl Acad Sci U S A 96: 6119-6124

Released	1998-10-21
Method	SOLUTION NMR
Organisms	Corynebacterium diphtheriae
Macromolecule	PROTEIN (DIPHTHERIA TOXIN REPRESSOR) (protein)

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1JQZ \| pdb_00001jqz	Download File View File

Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag.

Brych, S.R., Blaber, S.I., Logan, T.M., Blaber, M.

(2001) Protein Sci 10: 2587-2599

Released	2001-12-19
Method	X-RAY DIFFRACTION 1.65 Å
Organisms	Homo sapiens
Macromolecule	acidic fibroblast growth factor (protein)
Unique Ligands	FMT

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1JT3 \| pdb_00001jt3	Download File View File

Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Histidine Tag AND LEU 73 REPLACED BY VAL (L73V)

Brych, S.R., Blaber, S.I., Logan, T.M., Blaber, M.

(2001) Protein Sci 10: 2587-2599

Released	2001-12-19
Method	X-RAY DIFFRACTION 1.95 Å
Organisms	Homo sapiens
Macromolecule	acidic fibroblast growth factor (protein)
Unique Ligands	SO4

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1JT4 \| pdb_00001jt4	Download File View File

Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag AND VAL 109 REPLACED BY LEU (V109L)

Brych, S.R., Blaber, S.I., Logan, T.M., Blaber, M.

(2001) Protein Sci 10: 2587-2599

Released	2001-12-19
Method	X-RAY DIFFRACTION 1.78 Å
Organisms	Homo sapiens
Macromolecule	acidic fibroblast growth factor (protein)
Unique Ligands	FMT

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1JT5 \| pdb_00001jt5	Download File View File

Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag AND LEU 73 REPLACED BY VAL AND VAL 109 REPLACED BY LEU (L73V/V109L)

Brych, S.R., Blaber, S.I., Logan, T.M., Blaber, M.

(2001) Protein Sci 10: 2587-2599

Released	2001-12-19
Method	X-RAY DIFFRACTION 1.85 Å
Organisms	Homo sapiens
Macromolecule	acidic fibroblast growth factor (protein)
Unique Ligands	SO4

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1JT7 \| pdb_00001jt7	Download File View File

Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag AND LEU 44 REPLACED BY PHE AND LEU 73 REPLACED BY VAL AND VAL 109 REPLACED BY LEU (L44F/L73V/V109L)

Brych, S.R., Blaber, S.I., Logan, T.M., Blaber, M.

(2001) Protein Sci 10: 2587-2599

Released	2001-12-19
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Homo sapiens
Macromolecule	acidic fibroblast growth factor (protein)
Unique Ligands	FMT, SO4

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1JTC \| pdb_00001jtc	Download File View File

Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag AND LEU 44 REPLACED BY PHE (L44F)

Brych, S.R., Blaber, S.I., Logan, T.M., Blaber, M.

(2001) Protein Sci 10: 2587-2599

Released	2001-12-19
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Homo sapiens
Macromolecule	acidic fibroblast growth factor (protein)
Unique Ligands	FMT

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1M16 \| pdb_00001m16	Download File View File

Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag and Leu 44 Replaced with Phe (L44F), Leu 73 Replaced with Val (L73V), Val 109 Replaced with Leu (V109L) and Cys 117 Replaced with Val (C117V).

Brych, S.R., Kim, J., Spielmann, G.L., Logan, T.M., Blaber, M.

(2003) Protein Sci 12: 2704-2718

Released	2003-08-05
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Homo sapiens
Macromolecule	acidic fibroblast growth factor (protein)
Unique Ligands	FMT, SO4

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1NZK \| pdb_00001nzk	Download File View File

Crystal Structure of a Multiple Mutant (L44F, L73V, V109L, L111I, C117V) of Human Acidic Fibroblast Growth Factor

Brych, S.R., Kim, J., Logan, T.M., Blaber, M.

(2003) Protein Sci 12: 2704-2718

Released	2004-03-02
Method	X-RAY DIFFRACTION 1.95 Å
Organisms	Homo sapiens
Macromolecule	Acidic Fibroblast Growth Factor (protein)
Unique Ligands	FMT, SO4

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1P63 \| pdb_00001p63	Download File View File

Human Acidic Fibroblast Growth Factor. 140 Amino Acid Form with Amino Terminal His Tag and Leu111 Replaced with Ile (L111I)

Brych, S.R., Kim, J., Logan, T.M., Blaber, M.

(2003) Protein Sci 12: 2704-2718

Released	2004-05-11
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Homo sapiens
Macromolecule	ACIDIC FIBROBLAST GROWTH FACTOR (protein)
Unique Ligands	FMT, SO4

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1QVP \| pdb_00001qvp	Download File View File

C terminal SH3-like domain from Diphtheria toxin Repressor residues 144-226.

Wylie, G.P., Rangachari, V., Bienkiewicz, E.A., Marin, V., Bhattacharya, N., Love, J.F., Murphy, J.R., Logan, T.M.

(2005) Biochemistry 44: 40-51

Released	2004-11-02
Method	SOLUTION NMR
Organisms	Corynebacterium diphtheriae
Macromolecule	Diphtheria toxin repressor (protein)

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1QW1 \| pdb_00001qw1	Download File View File

Solution Structure of the C-Terminal Domain of DtxR residues 110-226

Wylie, G.P., Rangachari, V., Bienkiewicz, E.A., Love, J.F., Murphy, J.R., Logan, T.M.

(2005) Biochemistry 44: 40-51

Released	2005-03-15
Method	SOLUTION NMR
Organisms	Corynebacterium diphtheriae
Macromolecule	Diphtheria toxin repressor (protein)

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1TCE \| pdb_00001tce	Download File View File

SOLUTION NMR STRUCTURE OF THE SHC SH2 DOMAIN COMPLEXED WITH A TYROSINE-PHOSPHORYLATED PEPTIDE FROM THE T-CELL RECEPTOR, MINIMIZED AVERAGE STRUCTURE

Zhou, M.-M., Meadows, R.P., Logan, T.M., Yoon, H.S., Wade, W.R., Ravichandran, K.S., Burakoff, S.J., Feisk, S.W.

(1995) Proc Natl Acad Sci U S A 92: 7784-7788

Released	1997-05-15
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	PHOSPHOPEPTIDE OF THE ZETA CHAIN OF T CELL RECEPTOR (protein) SHC (protein)

1 to 14 of 14 Structures

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RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.

1BVH | pdb_00001bvh

SOLUTION STRUCTURE OF A LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE

1BYM | pdb_00001bym

SOLUTION STRUCTURES OF THE C-TERMINAL DOMAIN OF DIPHTHERIA TOXIN REPRESSOR

1JQZ | pdb_00001jqz

Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag.

1JT3 | pdb_00001jt3

Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Histidine Tag AND LEU 73 REPLACED BY VAL (L73V)

1JT4 | pdb_00001jt4

Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag AND VAL 109 REPLACED BY LEU (V109L)

1JT5 | pdb_00001jt5

Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag AND LEU 73 REPLACED BY VAL AND VAL 109 REPLACED BY LEU (L73V/V109L)

1JT7 | pdb_00001jt7

Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag AND LEU 44 REPLACED BY PHE AND LEU 73 REPLACED BY VAL AND VAL 109 REPLACED BY LEU (L44F/L73V/V109L)

1JTC | pdb_00001jtc

Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag AND LEU 44 REPLACED BY PHE (L44F)

1M16 | pdb_00001m16

Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag and Leu 44 Replaced with Phe (L44F), Leu 73 Replaced with Val (L73V), Val 109 Replaced with Leu (V109L) and Cys 117 Replaced with Val (C117V).

1NZK | pdb_00001nzk

Crystal Structure of a Multiple Mutant (L44F, L73V, V109L, L111I, C117V) of Human Acidic Fibroblast Growth Factor

1P63 | pdb_00001p63

Human Acidic Fibroblast Growth Factor. 140 Amino Acid Form with Amino Terminal His Tag and Leu111 Replaced with Ile (L111I)

1QVP | pdb_00001qvp

C terminal SH3-like domain from Diphtheria toxin Repressor residues 144-226.

1QW1 | pdb_00001qw1

Solution Structure of the C-Terminal Domain of DtxR residues 110-226

1TCE | pdb_00001tce

SOLUTION NMR STRUCTURE OF THE SHC SH2 DOMAIN COMPLEXED WITH A TYROSINE-PHOSPHORYLATED PEPTIDE FROM THE T-CELL RECEPTOR, MINIMIZED AVERAGE STRUCTURE

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Structure Determination Methodology

Scientific Name of Source Organism

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Experimental Method

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Release Date

Enzyme Classification Name

Symmetry Type

SCOP Classification

1BVH | pdb_00001bvh

1BYM | pdb_00001bym

1JQZ | pdb_00001jqz

1JT3 | pdb_00001jt3

1JT4 | pdb_00001jt4

1JT5 | pdb_00001jt5

1JT7 | pdb_00001jt7

1JTC | pdb_00001jtc

1M16 | pdb_00001m16

1NZK | pdb_00001nzk

1P63 | pdb_00001p63

1QVP | pdb_00001qvp

1QW1 | pdb_00001qw1

1TCE | pdb_00001tce