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234,785 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Structure Author = "Fyfe, P.K."

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Search Summary

This query matches 61 Structures.

Refinements

Structure Determination Methodology

experimental (61)

Scientific Name of Source Organism

	Human immunodeficiency virus 1 (13)
	Cereibacter sphaeroides (12)
	Leishmania major (6)
	Homo sapiens (4)
	Burkholderia cenocepacia J2315 (3)
	Staphylococcus aureus (3)
	Acinetobacter baumannii AYE (2)
	Escherichia coli K-12 (2)
	Plasmodium falciparum 3D7 (2)
	Serratia marcescens (2)

More...

Taxonomy

	Bacteria (31)
	Eukaryota (17)
	Riboviria (13)
	other sequences (1)

Experimental Method

X-RAY DIFFRACTION (61)

Polymer Entity Type

Protein (61)

Refinement Resolution (Å)

	1.0 - 1.5 (5)
	1.5 - 2.0 (16)
	2.0 - 2.5 (22)
	2.5 - 3.0 (15)
	3.0 - 3.5 (3)

Release Date

	1995 - 1999 (2)
	2000 - 2004 (3)
	2005 - 2009 (12)
	2010 - 2014 (21)
	2015 - 2019 (6)
	2020 - 2024 (17)

Enzyme Classification Name

	Lyases (8)
	Transferases (7)
	Oxidoreductases (3)
	Ligases (4)
	Hydrolases (2)

Membrane Protein Annotation

	MemProtMD (13)
	PDBTM (13)

Symmetry Type

	Asymmetric (30)
	Cyclic (28)
	Dihedral (6)

SCOP Classification

	Membrane and cell surface proteins and peptides (13)
	All beta proteins (13)
	Alpha and beta proteins (a/b) (6)
	Alpha and beta proteins (a+b) (4)
	All alpha proteins (2)

AllSelected

1 to 25 of 61 Structures

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1E14 \| pdb_00001e14	Download File View File

PHOTOSYNTHETIC REACTION CENTER MUTANT WITH PHE M197 REPLACED WITH ARG (CHAIN M, FM197R) AND GLY M203 REPLACED WITH ASP (CHAIN M, GM203D)

Fyfe, P.K., Ridge, J.P., McAuley, K.E., Cogdell, R.J., Isaacs, N.W., Jones, M.R.

(2000) Biochemistry 39: 5953

Released	2000-06-02
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Cereibacter sphaeroides
Macromolecule	Reaction center protein H chain (protein) Reaction center protein L chain (protein) Reaction center protein M chain (protein)
Unique Ligands	BCL, BPH, CDL, FE, LDA, SPN, U10

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1E6D \| pdb_00001e6d	Download File View File

PHOTOSYNTHETIC REACTION CENTER MUTANT WITH TRP M115 REPLACED WITH PHE (CHAIN M, WM115F) PHE M197 REPLACED WITH ARG (CHAIN M, FM197R)

Ridge, J.P., Fyfe, P.K., McAuley, K.E., Van Brederode, M.E., Robert, B., Van Grondelle, R., Isaacs, N.W., Cogdell, R.J., Jones, M.R.

(2000) Biochem J 351: 567

Released	2000-10-30
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Cereibacter sphaeroides
Macromolecule	PHOTOSYNTHETIC REACTION CENTER H SUBUNIT (protein) PHOTOSYNTHETIC REACTION CENTER L SUBUNIT (protein) PHOTOSYNTHETIC REACTION CENTER M SUBUNIT (protein)
Unique Ligands	BCL, BPH, FE, LDA, PO4, SPN, U10

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1MPS \| pdb_00001mps	Download File View File

PHOTOSYNTHETIC REACTION CENTER MUTANT WITH PHE M 197 REPLACED WITH ARG AND TYR M 177 REPLACED WITH PHE (CHAIN M, Y177F, F197R)

Mcauley-Hecht, K.E., Fyfe, P.K., Ridge, J.P., Prince, S., Hunter, C.N., Isaacs, N.W., Cogdell, R.J., Jones, M.R.

(1998) Biochemistry 37: 4740-4750

Released	1998-10-14
Method	X-RAY DIFFRACTION 2.55 Å
Organisms	Cereibacter sphaeroides
Macromolecule	PHOTOSYNTHETIC REACTION CENTER (protein)
Unique Ligands	BCL, BPH, FE2, LDA, PO4, SPN, U10

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1QOV \| pdb_00001qov	Download File View File

PHOTOSYNTHETIC REACTION CENTER MUTANT WITH ALA M260 REPLACED WITH TRP (CHAIN M, A260W)

McAuley, K.E., Fyfe, P.K., Ridge, J.P., Isaacs, N.W., Cogdell, R.J., Jones, M.R.

(1999) Proc Natl Acad Sci U S A 96: 14706

Released	1999-12-13
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Cereibacter sphaeroides
Macromolecule	PHOTOSYNTHETIC REACTION CENTER (protein)
Unique Ligands	BCL, BPH, CDL, CL, FE2, SPN, U10

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1UMX \| pdb_00001umx	Download File View File

PHOTOSYNTHETIC REACTION CENTER MUTANT WITH ARG M267 REPLACED WITH LEU (CHAIN M, R267L)

Fyfe, P.K., Isaacs, N.W., Cogdell, R.J., Jones, M.R.

(2004) Biochim Biophys Acta 1608: 11-22

Released	2004-06-29
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Cereibacter sphaeroides
Macromolecule	REACTION CENTER PROTEIN H CHAIN (protein) REACTION CENTER PROTEIN L CHAIN (protein) REACTION CENTER PROTEIN M CHAIN (protein)
Unique Ligands	BCL, BPB, FE, LDA, PO4, SPN, U10

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2BOZ \| pdb_00002boz	Download File View File

Photosynthetic Reaction Center Mutant With Gly M203 Replaced With Leu

Potter, J.P., Fyfe, P.K., Jones, M.R.

(2005) J Biological Chem 280: 27155

Released	2005-05-20
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Cereibacter sphaeroides
Macromolecule	REACTION CENTER PROTEIN H CHAIN (protein) REACTION CENTER PROTEIN L CHAIN (protein) REACTION CENTER PROTEIN M CHAIN (protein)
Unique Ligands	BCL, BPH, D10, FE, LDA, PO4, SPN, U10

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2C7V \| pdb_00002c7v	Download File View File

Structure of Trypanosoma brucei pteridine reductase (PTR1) in ternary complex with cofactor and the antifolate methotrexate

Dawson, A., Gibellini, F., Sienkiewicz, N., Fyfe, P.K., McLuskey, K., Fairlamb, A.H., Hunter, W.N.

(2006) Mol Microbiol 61: 1457

Released	2006-09-19
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Trypanosoma brucei brucei
Macromolecule	PTERIDINE REDUCTASE (protein)
Unique Ligands	ACT, MTX, NAP, NI

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2JIY \| pdb_00002jiy	Download File View File

PHOTOSYNTHETIC REACTION CENTER MUTANT WITH ALA M149 REPLACED WITH TRP (CHAIN M, AM149W)

Fyfe, P.K., Potter, J.A., Cheng, J., Williams, C.M., Watson, A.J., Jones, M.R.

(2007) Biochemistry 46: 10461

Released	2007-09-04
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Cereibacter sphaeroides
Macromolecule	REACTION CENTER PROTEIN H CHAIN (protein) REACTION CENTER PROTEIN L CHAIN (protein) REACTION CENTER PROTEIN M CHAIN (protein)
Unique Ligands	BCL, BPH, CDL, CL, D12, FE, LDA, PO4, SPN, U10

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2JJ0 \| pdb_00002jj0	Download File View File

PHOTOSYNTHETIC REACTION CENTER MUTANT WITH ALA M248 REPLACED WITH TRP (CHAIN M, AM248W)

Fyfe, P.K., Potter, J.A., Cheng, J., Williams, C.M., Watson, A.J., Jones, M.R.

(2007) Biochemistry 46: 10461

Released	2007-09-04
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Cereibacter sphaeroides
Macromolecule	REACTION CENTER PROTEIN H CHAIN (protein) REACTION CENTER PROTEIN L CHAIN (protein) REACTION CENTER PROTEIN M CHAIN (protein)
Unique Ligands	BCL, BPH, CDL, CL, FE, SPN, U10

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2JLA \| pdb_00002jla	Download File View File

Crystal structure of E.coli MenD, 2-succinyl-5-enolpyruvyl-6-hydroxy- 3-cyclohexadiene-1-carboxylate synthase - SeMet protein

Dawson, A., Fyfe, P.K., Hunter, W.N.

(2008) J Mol Biology 384: 1353

Released	2008-10-21
Method	X-RAY DIFFRACTION 2.81 Å
Organisms	Escherichia coli K-12
Macromolecule	2-SUCCINYL-5-ENOLPYRUVYL-6-HYDROXY-3-CYCLOHEXENE -1-CARBOXYLATE SYNTHASE (protein)
Unique Ligands	CL, MN, TPP

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2JLC \| pdb_00002jlc	Download File View File

Crystal structure of E.coli MenD, 2-succinyl-5-enolpyruvyl-6-hydroxy- 3-cyclohexadiene-1-carboxylate synthase - native protein

Dawson, A., Fyfe, P.K., Hunter, W.N.

(2008) J Mol Biology 384: 1353

Released	2008-10-21
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Escherichia coli K-12
Macromolecule	2-SUCCINYL-5-ENOLPYRUVYL-6-HYDROXY-3-CYCLOHEXENE -1-CARBOXYLATE SYNTHASE (protein)
Unique Ligands	MN, TPP

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2VOB \| pdb_00002vob	Download File View File

TRYPANOTHIONE SYNTHETASE

Fyfe, P.K., Oza, S.L., Fairlamb, A.H., Hunter, W.N.

(2008) J Biological Chem 283: 17672

Released	2008-05-06
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Leishmania major
Macromolecule	TRYPANOTHIONE SYNTHETASE (protein)
Unique Ligands	CL

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2VPM \| pdb_00002vpm	Download File View File

Trypanothione synthetase

Fyfe, P.K., Oza, S.L., Fairlamb, A.H., Hunter, W.N.

(2008) J Biological Chem 283: 17672

Released	2008-05-06
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Leishmania major
Macromolecule	TRYPANOTHIONE SYNTHETASE (protein)
Unique Ligands	BR, CL

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2VPS \| pdb_00002vps	Download File View File

Structure Of The Bifunctional Leishmania Major Trypanothione Synthetase-Amidase

Fyfe, P.K., Oza, S.L., Fairlamb, A.H., Hunter, W.N.

(2008) J Biological Chem 283: 17672

Released	2008-05-06
Method	X-RAY DIFFRACTION 2.75 Å
Organisms	Leishmania major
Macromolecule	TRYPANOTHIONE SYNTHETASE (protein)
Unique Ligands	BR, CL

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2VS0 \| pdb_00002vs0	Download File View File

Structural analysis of homodimeric staphylococcal aureus virulence factor EsxA

Sundaramoorthy, R., Fyfe, P.K., Hunter, W.N.

(2008) J Mol Biology 383: 603

Released	2008-08-26
Method	X-RAY DIFFRACTION 1.4 Å
Organisms	Staphylococcus aureus
Macromolecule	VIRULENCE FACTOR ESXA (protein)
Unique Ligands	CAC, ZN

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2WT9 \| pdb_00002wt9	Download File View File

Acinetobacter baumanii nicotinamidase pyrazinamidease

Fyfe, P.K., Rao, V.A., Zemla, A., Cameron, S., Hunter, W.N.

(2009) Angew Chem Int Ed Engl 48: 9176

Released	2009-11-10
Method	X-RAY DIFFRACTION 1.65 Å
Organisms	Acinetobacter baumannii AYE
Macromolecule	NICOTINAMIDASE (protein)
Unique Ligands	GOL, NIO, ZN

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2WTA \| pdb_00002wta	Download File View File

Acinetobacter baumanii nicotinamidase pyrazinamidease

Fyfe, P.K., Rao, V.A., Zemla, A., Cameron, S., Hunter, W.N.

(2009) Angew Chem Int Ed Engl 48: 9176

Released	2009-11-10
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Acinetobacter baumannii AYE
Macromolecule	NICOTINAMIDASE (protein)
Unique Ligands	CL, GOL, VGL, ZN

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2WX5 \| pdb_00002wx5	Download File View File

Hexa-coordination of a bacteriochlorophyll cofactor in the Rhodobacter sphaeroides reaction centre

Marsh, M., Frolov, D., Crouch, L.I., Fyfe, P.K., Robert, B., van Grondelle, R., Jones, M.R., Hadfield, A.T.

(2010) Biochemistry 49: 1882

Released	2010-02-09
Method	X-RAY DIFFRACTION 2.63 Å
Organisms	Cereibacter sphaeroides
Macromolecule	REACTION CENTER PROTEIN H CHAIN (protein) REACTION CENTRE PROTEIN L CHAIN (protein) REACTION CENTRE PROTEIN M CHAIN (protein)
Unique Ligands	BCL, BPH, CDL, FE, GOL, HTO, LDA, NA, SPN, U10

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2WYO \| pdb_00002wyo	Download File View File

Trypanosoma brucei glutathione synthetase

Fyfe, P.K., Alphey, M.S., Hunter, W.N.

(2010) Mol Biochem Parasitol 170: 93

Released	2010-01-19
Method	X-RAY DIFFRACTION 3.15 Å
Organisms	Trypanosoma brucei
Macromolecule	GLUTATHIONE SYNTHETASE (protein)
Unique Ligands	GSH, SO4

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2X75 \| pdb_00002x75	Download File View File

Staphylococcus aureus adenylosuccinate lyase

Fyfe, P.K., Dawson, A., Hutchison, M.T., Cameron, S., Hunter, W.N.

(2010) Acta Crystallogr D Biol Crystallogr 66: 881

Released	2010-03-09
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Staphylococcus aureus
Macromolecule	ADENYLOSUCCINATE LYASE (protein)
Unique Ligands	AMP, CL, OXL, P6G

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2X7J \| pdb_00002x7j	Download File View File

Structure of the menaquinone biosynthesis protein MenD from Bacillus subtilis

Dawson, A., Chen, M., Fyfe, P.K., Guo, Z., Hunter, W.N.

(2010) J Mol Biology 401: 253

Released	2010-07-14
Method	X-RAY DIFFRACTION 2.35 Å
Organisms	Bacillus subtilis
Macromolecule	2-SUCCINYL-5-ENOLPYRUVYL-6-HYDROXY-3-CYCLOHEXENE -1-CARBOXYLATE SYNTHASE (protein)
Unique Ligands	EDO, MN, NA, SO4, TPP

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2XMZ \| pdb_00002xmz	Download File View File

Structure of MenH from S. aureus

Dawson, A., Fyfe, P.K., Gillet, F., Hunter, W.N.

(2011) BMC Struct Biol 11: 19

Released	2011-05-25
Method	X-RAY DIFFRACTION 1.94 Å
Organisms	Staphylococcus aureus
Macromolecule	HYDROLASE, ALPHA/BETA HYDROLASE FOLD FAMILY (protein)

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2XOX \| pdb_00002xox	Download File View File

Crystal structure of pteridine reductase (PTR1) from Leishmania donovani

Barrack, K.L., Tulloch, L.B., Burke, L.A., Fyfe, P.K., Hunter, W.N.

(2011) Acta Crystallogr Sect F Struct Biol Cryst Commun 67: 33

Released	2011-01-12
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Leishmania donovani
Macromolecule	PTERIDINE REDUCTASE (protein)
Unique Ligands	SO4

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2Y4R \| pdb_00002y4r	Download File View File

CRYSTAL STRUCTURE OF 4-AMINO-4-DEOXYCHORISMATE LYASE FROM PSEUDOMONAS AERUGINOSA

O'Rourke, P.E.F., Eadsforth, T.C., Fyfe, P.K., Shepard, S.M., Agacan, M., Hunter, W.N.

(2011) PLoS One 6: 24158

Released	2011-01-19
Method	X-RAY DIFFRACTION 1.75 Å
Organisms	Pseudomonas aeruginosa PAO1
Macromolecule	4-AMINO-4-DEOXYCHORISMATE LYASE (protein)
Unique Ligands	CL, EDO, GOL, PEG, PG4, PLP, SO4

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2YNQ \| pdb_00002ynq	Download File View File

Crystal Structure of Geobacillus thermodenitrificans EssB extracellular fragment

Zoltner, M., Fyfe, P.K., Hunter, W.N.

(2013) Structure 21: 595

Released	2012-12-05
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Geobacillus thermodenitrificans NG80-2
Macromolecule	ESSB (protein)
Unique Ligands	CL, GOL, MLI, NA

1 to 25 of 61 Structures

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification

1E14 | pdb_00001e14

1E6D | pdb_00001e6d

1MPS | pdb_00001mps

1QOV | pdb_00001qov

1UMX | pdb_00001umx

2BOZ | pdb_00002boz

2C7V | pdb_00002c7v

2JIY | pdb_00002jiy

2JJ0 | pdb_00002jj0

2JLA | pdb_00002jla

2JLC | pdb_00002jlc

2VOB | pdb_00002vob

2VPM | pdb_00002vpm

2VPS | pdb_00002vps

2VS0 | pdb_00002vs0

2WT9 | pdb_00002wt9

2WTA | pdb_00002wta

2WX5 | pdb_00002wx5

2WYO | pdb_00002wyo

2X75 | pdb_00002x75

2X7J | pdb_00002x7j

2XMZ | pdb_00002xmz

2XOX | pdb_00002xox

2Y4R | pdb_00002y4r

2YNQ | pdb_00002ynq