Lysine (abbreviated as Lys or K) is an α-amino acid with the chemical formula HO2CCH(NH2)(CH2)4NH2. This amino acid is an essential amino acid, which means that humans cannot synthesize it. Its codons are AAA and AAG. Lysine is a base, as are arginine and histidine. The ε-amino group acts as a site for hydrogen binding and a general base in catalysis. Common posttranslational modifications include methylation of the ε-amino group, giving methyl-, dimethyl-, and trimethyllysine. The latter occurs in calmodulin. Other posttranslational modifications include acetylation. Collagen contains hydroxylysine which is derived from lysine by lysyl hydroxylase. O-Glycosylation of lysine residues in the endoplasmic reticulum or Golgi apparatus is used to mark certain proteins for secretion from the cell.
Synonyms
L-Lysine
Lysine acid
6-ammonio-L-norleucine
Lysine dihydrate
Lysinum
(S)-2,6-diaminohexanoic acid
L-lys
L-Lysin
LYS
Lysine monohydrate
Lysine
Lysine hydrochloride
L-2,6-Diaminocaproic acid
Lysine acetate
Lysina
(S)-lysine
(S)-α,ε-diaminocaproic acid
Brand Names
ProcalAmine
Olimel 3.3% E
Smofkabiven Electrolyte Free
Primene
Aminosyn 3.5% M
Aminosyn II 8.5% With 50% Dextrose
Aminosyn II 7% With 10% Dextrose
Plenamine
Clinimix E
Aminosyn II In Dextrose Injection
Essepna
Synthamin
Renamin (amino Acids) Injection
20% Prosol
Olimel 5.7% E
HepatAmine
RenAmin
Travasol Inj Without Electrolytes 8.5%
Aminosyn-PF
TrophAmine
Imubolic
Perikabiven
Aminosyn II 7% With 50% Dextrose
Aminosyn II 5% Inj
2.75% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose Quickmix
2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose
4.25% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix
Aminosyn RF Injection
Effervescent Potassium Chloride
8.5% Freamine III
5% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose
Lysakare
Olimel 4.4% E
Travasol Amino Acid Inj 5.5%
Clinimix
4.25%trav. Amino Acid InJ.W.O.elect.5%dext.
Kabiven
Olimel 4.4%
Olimel 7.6% E
4.25% Travasol Amino Acid Injection Without Electrlytes In 10% Dextrose
Smofkabiven Extra Nitrogen
Aminosyn II 7% Injection
Aminosyn-PF 7%
2.75% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix
Aminosyn II and Dextrose
Novamine
Aminosyn II with Electrolytes
Aminosyn II 7% M In 10% Dextrose(dual Chamber)
5% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose
Travasol Inj Without Electrolytes 5.5%
4.25% Amino Acid Injection Without Electrolytes In 20% Dextrose Quickmix
Clinimix 2.5% Travasol Aa Without Electrolytes In 10% Dextrose Injec
Travasol
Vamin N
Aminosyn
Primene 10%-liq IV
Smofkabiven Extra Nitrogen Electrolyte Free
Aminosyn 8.5%
Aminosyn II 10% With Electrolytes
FreAmine III
Aminosyn 8.5% Injection With Electrolytes
2.75%travasol Amino Acid InJ.W.eleC.W.5%dex.
Vamin 18 Electrolyte-free
Nutrineal Pd4
Aminosyn Sulfite Free
4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose
4.25% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose
4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose Quickmix
Aminosyn HF
Aminosyn 10% W Electrolytes
Aminosyn-PF 10%
4.25% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose
Periolimel 2.5% E
Olimel 7.6%
NephrAmine
2.5% Travasol Amino Acid Injection Without Electrolytes In 10% Dextrose Quickmix
4.25% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose
Smofkabiven
5% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose
Aminosyn II
Aminosyn 7%
ProSol
Aminosyn II 8.5% Injection
Olimel 5.7%
2.75% Travas. Amino Acid InJ.W.elecw.25%dex
Hepatasol
Aminosyn 5%
Clinisol
Premasol - sulfite-free (Amino Acid)
Aminosyn RF
Quick Mix 2.5% Travasol Aa With Electrolytes With 25% Dextrose Injec
4.25%travasol Amino Acid InJ.W.elecw.5%dex.
Travasol E
Xyzmune
FreAmine HBC
Aminosyn II 8.5% M In 20% Dextrose (dual Chamber)
Smofkabiven Peripheral
Aminosyn II with Electrolytes in Dextrose with Calcium
4.25% Travasol Amino Acid Without Electrolytes In 5% Dextrose Quickmix
4.25% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose
Aminosyn II in Dextrose
2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose Clinimix
Primene 10%
2.5%travasol Amino Acid InJ.W.eleC.W.25%dex
Travasol Amino Acid Inj 8.5%
Nephramine Liq IV
Indication
Supplemental lysine has putative anti-herpes simplex virus activity. There is preliminary research suggesting that it may have some anti-osteoporotic activity.
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
