UTP

URIDINE 5'-TRIPHOSPHATE


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Chemical Component Summary

NameURIDINE 5'-TRIPHOSPHATE
Identifiers[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methyl (hydroxy-phosphonooxy-phosphoryl) hydrogen phosphate
FormulaC9 H15 N2 O15 P3
Molecular Weight484.141
TypeNON-POLYMER
Isomeric SMILESC1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO[P@@](=O)(O)O[P@@](=O)(O)OP(=O)(O)O)O)O
InChIInChI=1S/C9H15N2O15P3/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1
InChIKeyPGAVKCOVUIYSFO-XVFCMESISA-N

Chemical Details

Formal Charge0
Atom Count44
Chiral Atom Count6
Bond Count45
Aromatic Bond Count6

Drug Info: DrugBank

DrugBank IDDB04005 
NameUridine 5'-triphosphate
Groups
  • investigational
  • experimental
DescriptionUridine 5'-(tetrahydrogen triphosphate). A uracil nucleotide containing three phosphate groups esterified to the sugar moiety.
Synonyms
  • Uridine 5'-triphosphate
  • Uridine triphosphate
Categories
  • Nucleic Acids, Nucleotides, and Nucleosides
  • Nucleotides
  • Pyrimidine Nucleotides
  • Pyrimidines
  • Ribonucleotides
CAS number63-39-8

Drug Targets

NameTarget SequencePharmacological ActionActions
Uridine-cytidine kinase 2MAGDSEQTLQNHQQPNGGEPFLIGVSGGTASGKSSVCAKIVQLLGQNEVD...unknown
Genome polyproteinMSTNPKPQRKTKRNTNRRPQDVKFPGGGQIVGGVYLLPRRGPRLGVRATR...unknown
Genome polyproteinMSTNPKPQRKTKRNTNRRPQDVKFPGGGQIVGGVYLLPRRGPRLGVRAPR...unknown
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource NameReference
Pharos CHEMBL336296
PubChem 6133
ChEMBL CHEMBL336296
ChEBI CHEBI:15713